RP105 is a new innate immune receptor for Mycobacterium tuberculosis

RP105是结核分枝杆菌的新型先天免疫受体

• 批准号: nhmrc : 1049087
• 负责人: A/Pr Antje Blumenthal
• 金额: $ 35.05万
• 依托单位: The University of Queensland
• 依托单位国家: 澳大利亚
• 项目类别: Project Grants
• 财政年份: 2013
• 资助国家: 澳大利亚
• 起止时间: 2013-01-01 至 2016-12-31
• 项目状态: 已结题
• 来源: https://researchdata.edu.au/rp105-new-innate-mycobacterium-tuberculosis/112057
• 关键词: RP105; new; innate; immune; receptor

Tuberculosis (TB) is a major global health threat that causes 1.7 million deaths every year. This study will characterise the interactions between the bacteria that cause TB and a new immune sensor. We found that this sensor is involved in controlling TB and this project will determine how it contributes to the immune defence against the infection. Such knowledge will help improve patient management and develop an effective vaccine and better treatments for this devastating disease.

结核病是一个重大的全球健康威胁，每年导致170万人死亡。这项研究将描述导致结核病的细菌与一种新的免疫传感器之间的相互作用。我们发现这种传感器参与了结核病的控制，这个项目将确定它如何有助于对感染的免疫防御。这些知识将有助于改善患者管理，并为这种毁灭性的疾病开发有效的疫苗和更好的治疗方法。