Archiving Additional Waves of the Swedish Adoption/Twin Study of Aging (SATSA)

归档瑞典收养/双胞胎老龄化研究 (SATSA) 的其他浪潮

基本信息

批准号：
8368292
负责人：
NANCY L PEDERSEN
金额：
$ 5.4万
依托单位：
KAROLINSKA INSTITUTE
依托单位国家：
美国
项目类别：
财政年份：
2012
资助国家：
美国
起止时间：
2012-08-01 至 2013-07-31
项目状态：
已结题

来源：
https://reporter.nih.gov/project-details/8368292
关键词：
Activities of Daily Living Address Adoption Adult Age Aging Aging-Related Process Archives Behavioral Behavioral Genetics California Cognition Cognitive Collaborations Communities Complex Confidentiality Data Data Analyses Data Collection Data Files Data Set Deposition Development Documentation Educational workshop Elderly Emotional Ensure Florida Foundations Funding Genetic Genetic Risk Gerontology Grant Half-Life Health behavior Impaired cognition Indiana Individual Institutes Institution Knowledge Life Style Linear Models Longitudinal Studies Los Angeles Mails Measurement Measures Meta-Analysis Michigan Minnesota Mission NIH Program Announcements National Institute on Aging Occupational Outcome Participant Patient Self-Report Pennsylvania Personal Satisfaction Personality Persons Phenotype Physical Function Probability Process Psychosocial Stress Public Health Questionnaires Registries Research Research Personnel Resources Sample Size Sampling Social Environment Social Impacts Socioeconomic Status Source Sweden Testing Twin Multiple Birth Twin Studies United States National Institutes of Health Universities Virginia Well in self West Virginia Work aged cognitive function computerized data modeling experience healthy aging improved interest lifestyle factors member physical conditioning psychologic ranpirnase resilience response social socioeconomics trait user-friendly

项目摘要

DESCRIPTION (provided by applicant): The purpose of the work described in this application is to archive the Swedish Adoption/Twin Study of Aging (SATSA) data collected by NIH Grant No. R01AG10175 with the Inter-University Consortium for Political and Social Research (ICPSR) and in collaboration with the National Archive of Computerized Data on Aging (NACDA) at the University of Michigan. Data archiving serves the purpose of enabling other investigators to make use of this resource, both by itself and in multi-study efforts across different studies with similar information. Increasing the availability of these data may facilitat additional harmonization activities, as highlighted in NIA harmonization workshops in Los Angeles (May 2011) and Bethesda (November 2011). The archiving activities described here entail converting the complex questionnaire and in-person testing data into controlled access public use files with user-friendly formats that facilitate data use. SATSA includes multiple longitudinal waves of assessment of cognitive functioning, physical health, and well-being, via both self-report questionnaire (Q) and in-person testing (IPT). Previously, the first 4 questionnaire waves and the first 3 waves of in-person testing have been archived at the ICPSR. The data archiving proposed here adds 2 more Q waves and 2 more IPT waves, and would make available data from 2174 participants with up to 6 waves of questionnaire data and from a subset of 859 individuals aged 50 and older with up to 5 in-person assessments. Whereas 3 waves of assessment are adequate to support modeling linear changes with age, 5 waves of assessment provide sufficient data for modeling more complex trajectories of change with age: accelerating decline and multiple change points. Assessment in multiple domains allows for testing cross-domain relationships. Importantly, adding 2 more waves of IPT and Q data to the data archive increases the proportion of the sample that has participated in at least 3 waves of measurement. The activities described in this application include formatting datasets and creating documentation consistent with ICPSR standards. Direct identifiers are already removed; in the course of preparing data files for archiving, we will further de-identify the data o protect the confidentiality of participants. The completed SATSA data archive thus has a potential to address many secondary analysis questions concerning psychological and social processes in aging and the behavior genetics of aging. PUBLIC HEALTH RELEVANCE: Data archiving is encouraged by NIH as a way to make data as widely and freely available as possible to the research community while safeguarding the confidentiality of participants. Those participating in the original study were motivated to contribute to knowledge about the aging process and sources of cognitive decline in older adults. Archiving serves the aspirations of those participants and the interests of public health by permitting the fullest possible use of the information that was collected. The research questions that can be addressed by those using the data archive are of intense public interest, namely, discovering potentially modifiable lifestyle factors and health behaviors that improve the probability for maintaining functioning across domains in old age.

描述（由申请人提供）：本申请中描述的工作的目的是归档瑞典的收养/双胞胎研究（SATSA）（NIH Grant No. r01AG10175）收集的数据（SATSA）数据与大学政治和社会研究联盟（ICPSR）（ICPSR）（ICPSR）（ICPSR）（ICPSR）（ICPSR）（ICPSR）以及与Aging Aging Ancing（Nacda）的全国性数据合作（nacda）合作。数据归档的目的是使其他研究人员能够本身以及在不同研究的多个研究工作中利用此资源，并具有相似的信息。如NIA在洛杉矶（2011年5月）和贝塞斯达（2011年11月）的NIA协调研讨会（2011年11月）所强调的那样，增加这些数据的可用性可能会促进其他协调活动。这里描述的归档活动需要将复杂的问卷调查和面对面的测试数据转换为具有促进数据使用的用户友好格式的受控访问公共使用文件。 SATSA包括通过自我报告调查表（Q）和个人测试（IPT）进行认知功能，身体健康和福祉的多次纵向评估。以前，在ICPSR上已经存档了前4个问卷波和前3个亲自测试的波。此处提出的数据存档增加了2个Q波和2个IPT波，并将提供来自2174名参与者的可用数据，其中有多达6个问卷数据，以及859名50岁及以上的人的子集，最多5个，最多5个人工评估。尽管3波的评估波足以支持随着年龄的增长的线性变化的模型，但5个评估波提供了足够的数据来建模更复杂的变化轨迹随着年龄的增长：加速下降和多个变更点。多个领域的评估允许测试跨域关系。重要的是，在数据存档中添加2个ipt和Q数据的另外2个波会增加参与至少3个的样本比例测量波。本应用程序中描述的活动包括格式化数据集和创建与ICPSR标准一致的文档。直接标识符已被删除；在准备归档数据文件的过程中，我们将进一步识别数据o保护参与者的机密性。因此，已完成的SATSA数据存档有可能解决有关衰老和衰老行为遗传学的心理和社会过程的许多二级分析问题。公共卫生相关性：NIH鼓励数据归档，以此作为使研究社区尽可能广泛，自由地获得数据的一种方式，同时维护参与者的机密性。参与原始研究的人是有动力为了解老年人的衰老过程和认知能力下降来源的知识做出贡献。归档通过允许最大程度地使用收集的信息来满足这些参与者的愿望和公共卫生的利益。使用数据档案的人可以解决的研究问题具有强烈的公众兴趣，即发现潜在的可修改的生活方式因素和健康行为，以提高老年范围内维持跨领域功能的可能性。