2012 Myelin Gordon Research Conference & Gordon Research Seminar

2012年髓磷脂戈登研究会议

• 批准号: 8317793
• 负责人: JAMES SALZER
• 金额: $ 2万
• 依托单位: GORDON RESEARCH CONFERENCES
• 依托单位国家: 美国
• 财政年份: 2012
• 资助国家: 美国
• 起止时间: 2012-03-01 至 2013-02-28
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/8317793
• 关键词: Adult; Affect; Area; Attention; Axon; Biology; Cells; Central Nervous System Diseases; Clinical; Collaborations; Demyelinations; Development; Disabled Persons; Disease; Ensure; Environment; Equilibrium; Feedback; Fostering; Funding; Gender; Goals; Immune system; Indium; Injury; Italy; Mentors; Minority Groups; Multiple Sclerosis; Myelin; Natural regeneration; Nerve Fibers; Nervous system structure; Neurodegenerative Disorders; Neuroglia; Neurons; Oligodendroglia; Oral; Participant; Pathogenesis; Pathology; Peripheral Nervous System Diseases; Postdoctoral Fellow; Request for Applications; Research; Research Personnel; Schwann Cells; Science; Scientist; Signal Transduction; Staging; Thinking; Time; Travel; Woman; career; career development; design; dysmyelination; graduate student; innovation; insight; interest; meetings; myelination; neurobehavioral disorder; next generation; novel therapeutics; posters; programs; remyelination; repaired; symposium

DESCRIPTION (provided by applicant): With this application, we are requesting support for the 2012 Gordon Research Symposium and Conference on Myelin, to be held in Barga, Italy from April 28 - May 5, 2012. Understanding of the biology of myelinating glia in the PNS and CNS continues to advance rapidly. Since the last Myelin GRC in Ventura, CA in February 2010, major new insights have emerged regarding the differentiation of myelinating glia, their interactions with axons, and their potential for myelin repair. New extrinsic signals that either promote or inhibit myelination have been identified, which may direct efforts at myelin repair. There is a growing appreciation of the extent of ongoing myelination in the adult CNS and of the importance of neuronal activity in regulating the oligodendrocyte genesis and differentiation. Oligodendrocyte pathology is being recognized as an important component in a broad array of CNS diseases, including neurodegenerative disorders, not just multiple sclerosis. Recent studies indicate that the immune system not only contributes to myelin pathology but may also affect remyelination. The program for the 11th Gordon Conference "Myelin: biology and pathobiology" is designed to bring together leading investigators in the field to highlight these and other advances, to foster a vigorous exchange of ideas, and to accelerate research. We have made an effort to limit overlap with speakers from previous meetings and to highlight emerging topics. The vitality of myelin biology research depends on fostering the next generation of investigators, including newly independent scientists. To this end, we have invited a number of young investigators to speak at this meeting, in both regular and short talks. Senior investigators will provide overviews of the field as session chairs and also speak. Appropriate attention will be paid to ensure gender balance among the roster of speakers. To ensure that the latest, most exciting results are presented, some poster presenters will be selected for short talks. To further highlight junior investigators, this year's meeting for the first time will beginwith a Gordon Research Seminar (GRS) on myelin. We expect more than 50 young investigators, i.e. graduate students and post-doctoral fellows, to attend. The GRS will focus on oligodendrocyte biology and remyelination; it will provide a unique forum for young investigators to meet and interact, present cutting edge research, and develop collaborations. To further encourage the participation of trainees in the field of myelin biology, we will offer stipends for travel and registration as funds permit. All attendees will be expected to contribute an oral or poster presentation. We believe that poster sessions are a key element in fostering productive interactions between scientists with different expertise. In keeping with the goals of the Gordon Research Conference, such interactions will provide impetus and accelerate progress in the field of myelin biology.

描述（由申请人提供）：通过本申请，我们请求支持将于2012年4月28日至5月5日在意大利巴尔加举行的2012年戈登研究研讨会和髓鞘会议。对PNS和CNS中髓鞘生成胶质细胞的生物学的理解继续迅速发展。自2010年2月在加利福尼亚州文图拉举行的最后一次髓磷脂GRC以来，关于髓鞘形成胶质细胞的分化、它们与轴突的相互作用以及它们对髓磷脂修复的潜力已经出现了重大的新见解。促进或抑制髓鞘形成的新的外在信号已经被鉴定，这可能指导髓鞘修复的努力。越来越多的人认识到成年中枢神经系统髓鞘形成的程度以及神经元活性在调节少突胶质细胞发生和分化中的重要性。少突胶质细胞病理学被认为是广泛的CNS疾病的重要组成部分，包括神经退行性疾病，而不仅仅是多发性硬化症。最近的研究表明，免疫系统不仅有助于髓鞘病理，但也可能影响髓鞘再生。第11届戈登会议“髓鞘：生物学和病理学”的计划旨在汇集该领域的领先研究人员，以突出这些和其他进展，促进思想的积极交流，并加速研究。我们努力限制与前几次会议发言者的重叠，并突出新出现的议题。髓鞘生物学研究的活力取决于培养下一代研究人员，包括新的独立科学家。为此，我们邀请了一些年轻的调查人员在本次会议上发言，包括定期和简短的会谈。高级调查员将作为会议主席提供该领域的概况，并发言。将适当注意确保发言者名册中的性别平衡。为了确保展示最新、最令人兴奋的成果，将选择一些海报展示者进行简短的演讲。为了进一步突出初级研究人员，今年的会议将首次举办关于髓鞘的戈登研究研讨会（GRS）。我们预计将有50多名年轻的研究人员，即研究生和博士后研究员参加。GRS将专注于少突胶质细胞生物学和髓鞘再生;它将为年轻的研究人员提供一个独特的论坛，以满足和互动，目前的前沿研究，并发展合作。为了进一步鼓励学员参与髓磷脂生物学领域的工作，我们将在资金允许的情况下提供旅行和注册津贴。所有与会者将被要求提供口头或海报介绍。我们认为，海报会议是促进具有不同专业知识的科学家之间富有成效的互动的关键因素。为了与戈登研究会议的目标保持一致，这种相互作用将提供动力并加速髓鞘生物学领域的进展。