2012 Myelin Gordon Research Conference & Gordon Research Seminar

2012年髓磷脂戈登研究会议

• 批准号: 8317793
• 负责人: JAMES SALZER
• 金额: $ 2万
• 依托单位: GORDON RESEARCH CONFERENCES
• 依托单位国家: 美国
• 财政年份: 2012
• 资助国家: 美国
• 起止时间: 2012-03-01 至 2013-02-28
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/8317793
• 关键词: Adult; Affect; Area; Attention; Axon; Biology; Cells; Central Nervous System Diseases; Clinical; Collaborations; Demyelinations; Development; Disabled Persons; Disease; Ensure; Environment; Equilibrium; Feedback; Fostering; Funding; Gender; Goals; Immune system; Indium; Injury; Italy; Mentors; Minority Groups; Multiple Sclerosis; Myelin; Natural regeneration; Nerve Fibers; Nervous system structure; Neurodegenerative Disorders; Neuroglia; Neurons; Oligodendroglia; Oral; Participant; Pathogenesis; Pathology; Peripheral Nervous System Diseases; Postdoctoral Fellow; Request for Applications; Research; Research Personnel; Schwann Cells; Science; Scientist; Signal Transduction; Staging; Thinking; Time; Travel; Woman; career; career development; design; dysmyelination; graduate student; innovation; insight; interest; meetings; myelination; neurobehavioral disorder; next generation; novel therapeutics; posters; programs; remyelination; repaired; symposium

DESCRIPTION (provided by applicant): With this application, we are requesting support for the 2012 Gordon Research Symposium and Conference on Myelin, to be held in Barga, Italy from April 28 - May 5, 2012. Understanding of the biology of myelinating glia in the PNS and CNS continues to advance rapidly. Since the last Myelin GRC in Ventura, CA in February 2010, major new insights have emerged regarding the differentiation of myelinating glia, their interactions with axons, and their potential for myelin repair. New extrinsic signals that either promote or inhibit myelination have been identified, which may direct efforts at myelin repair. There is a growing appreciation of the extent of ongoing myelination in the adult CNS and of the importance of neuronal activity in regulating the oligodendrocyte genesis and differentiation. Oligodendrocyte pathology is being recognized as an important component in a broad array of CNS diseases, including neurodegenerative disorders, not just multiple sclerosis. Recent studies indicate that the immune system not only contributes to myelin pathology but may also affect remyelination. The program for the 11th Gordon Conference "Myelin: biology and pathobiology" is designed to bring together leading investigators in the field to highlight these and other advances, to foster a vigorous exchange of ideas, and to accelerate research. We have made an effort to limit overlap with speakers from previous meetings and to highlight emerging topics. The vitality of myelin biology research depends on fostering the next generation of investigators, including newly independent scientists. To this end, we have invited a number of young investigators to speak at this meeting, in both regular and short talks. Senior investigators will provide overviews of the field as session chairs and also speak. Appropriate attention will be paid to ensure gender balance among the roster of speakers. To ensure that the latest, most exciting results are presented, some poster presenters will be selected for short talks. To further highlight junior investigators, this year's meeting for the first time will beginwith a Gordon Research Seminar (GRS) on myelin. We expect more than 50 young investigators, i.e. graduate students and post-doctoral fellows, to attend. The GRS will focus on oligodendrocyte biology and remyelination; it will provide a unique forum for young investigators to meet and interact, present cutting edge research, and develop collaborations. To further encourage the participation of trainees in the field of myelin biology, we will offer stipends for travel and registration as funds permit. All attendees will be expected to contribute an oral or poster presentation. We believe that poster sessions are a key element in fostering productive interactions between scientists with different expertise. In keeping with the goals of the Gordon Research Conference, such interactions will provide impetus and accelerate progress in the field of myelin biology.

描述（由申请人提供）：通过此申请，我们请求支持将于 2012 年 4 月 28 日至 5 月 5 日在意大利巴尔加举行的 2012 年戈登研究研讨会和髓鞘质会议。对 PNS 和 CNS 中髓鞘胶质细胞生物学的了解继续快速推进。自 2010 年 2 月在加利福尼亚州文图拉举行的最后一次髓磷脂 GRC 以来，关于髓鞘神经胶质细胞的分化、它们与轴突的相互作用以及髓磷脂修复潜力的重大新见解已经出现。已经确定了促进或抑制髓鞘形成的新外在信号，这可能会指导髓鞘修复的努力。人们越来越认识到成人中枢神经系统中持续髓鞘形成的程度以及神经元活动在调节少突胶质细胞发生和分化中的重要性。少突胶质细胞病理学被认为是多种中枢神经系统疾病的重要组成部分，包括神经退行性疾病，而不仅仅是多发性硬化症。最近的研究表明，免疫系统不仅有助于髓鞘质病理学，还可能影响髓鞘再生。第 11 届戈登会议的议程“髓磷脂：生物学和病理学”旨在汇集该领域的领先研究人员，以突出这些进展和其他进展，促进积极的思想交流，并加速研究。我们努力限制与之前会议发言者的重叠，并强调新出现的主题。髓磷脂生物学研究的活力取决于培养下一代研究人员，包括新独立的科学家。为此，我们邀请了一些年轻的研究者在这次会议上发言，包括定期报告和简短报告。高级研究人员将作为会议主席提供该领域的概述并发表讲话。将适当注意确保发言者名单中的性别平衡。为确保展示最新、最精彩的成果，我们将挑选一些海报展示者进行简短的演讲。为了进一步突出初级研究人员，今年的会议首次将以髓磷脂戈登研究研讨会（GRS）开始。我们预计将有超过 50 名年轻研究人员，即研究生和博士后研究员参加。 GRS 将重点关注少突胶质细胞生物学和髓鞘再生；它将为年轻研究人员提供一个独特的论坛，让他们见面和互动、展示前沿研究并发展合作。为了进一步鼓励学员参与髓磷脂生物学领域，我们将在资金允许的情况下提供差旅和注册补贴。所有与会者都需要进行口头或海报展示。我们相信海报会议是促进具有不同专业知识的科学家之间富有成效的互动的关键因素。为了与戈登研究会议的目标保持一致，这种相互作用将提供动力并加速髓磷脂生物学领域的进展。