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中文摘要
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凯克生物物理设施是一个生物结构研究中心,由 西北大学结构生物学中心,由W.M.凯克基金会捐赠 以及来自美国国立卫生研究院、赖斯基金会和罗伯特·H·卢里综合基金会的额外支持 癌症中心。自1999年4月1日以来,它是西北大学的共享资源之一,有21个 具有多个附件的先进研究仪器。该设施的全套状态- 先进的仪器使其成为研究结构和相互作用的独特资源 生物大分子和合成大分子。负担得起的用户费用、个人培训和仪器 维护良好、维修及时、24小时全天候可用的服务 这吸引了越来越多的用户。例如,在2005财年,该设施 欢迎来自65个西北大学研究小组的267名个人用户。目前,凯克设施 有498个活跃用户(当前西北大学的学生、博士后研究员或教职员工 在需要时授权使用Keck设施设备)。特别是,该中心有 成为癌症研究的关键设施,因为使用该设施的大多数研究小组 隶属于罗伯特·H·卢里综合癌症中心。该设施的一个重要目标是 吸引新用户,使他们能够产生更多、更好的科学成果 有可能。
英文摘要
The Keck Biophysics Facility is a center for biostructural research, which was created in 1998 by Northwestern University's Center for Structural Biology with grants from the W.M. Keck Foundation and additional support from NIH, the Rice Foundation, and the Robert H. Lurie Comprehensive Cancer Center. Since April 1, 1999 it is one of Northwestern's Shared Resources, featuring 21 advanced research instruments with multiple accessories. The facility's comprehensive set of stateof- the-art instruments make it a unique resource for the study of the structures and interactions of biological and synthetic macro-molecules. Affordable user fees, individual training, and instruments that are well maintained, promptly repaired, and accessible on a 24 hour/ 7 day basis are services which attract an ever-increasing pool of users. For example, for fiscal year 2005, the facility welcomed 267 individual users from 65 Northwestern research groups. Presently, the Keck Facility has 498 active users (current Northwestern students, post-doctoral fellows, or faculty who are authorized to use Keck Facility equipment when the need arises). In particular, the center has become a key facility for cancer research, as the majority of research groups using the facility are affiliated with the Robert H. Lurie Comprehensive Cancer Center. An important goal of the facility is to attract new users, enabling them to produce more, and better, science than otherwise would be possible.
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Novel targeted therapies for HPV-associated Non-AIDS-defining cancers (Biospecimens/Biocohort)
Genomic and Microenvironment Analysis of HIV-Associated Diffuse Large B-cell Lymphoma (Immuno/Microenvironment)
Caribbean Investigation of Cancer Stigma and its effect on Cervical Cancer Screening and HPV Vaccination
Creating an Efficient Clinical Trial Build System Via the Clinical Trials Rapid Activation Consortium (CTRAC)
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