Mentoring and Research in Cancer Palliative Care

癌症姑息治疗的指导和研究

• 批准号: 8312330
• 负责人: Aminah Jatoi
• 金额: $ 19.49万
• 依托单位: MAYO CLINIC ROCHESTER
• 依托单位国家: 美国
• 财政年份: 2008
• 资助国家: 美国
• 起止时间: 2008-09-02 至 2014-08-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/8312330
• 关键词: Advanced Malignant Neoplasm; Adverse event; American; Anorexia; Bereavement; Biolectric Impedance; Body Weight decreased; Cancer Patient; Clinic; Clinical Research; Clinical Trials; Comprehensive Cancer Center; Creatine; Desire for food; Diagnosis; Ensure; Environment; Goals; Growth; Laboratories; Malignant Neoplasms; Manuscripts; Mentors; Patient Care; Placebos; Publishing; Research; Research Infrastructure; Research Personnel; Resources; Severities; Symptoms; Time; Toxic effect; Translational Research; Treatment-Related Cancer; Weight; cancer anorexia; cancer palliative treatment; cancer therapy; career; end of life; meetings; success; translational study

DESCRIPTION (provided by applicant): Last year, approximately 1,400,000 Americans were diagnosed with cancer, and approximately 560,000 died from it. When one considers the adverse events associated with cancer treatment, the wide constellation and severity of end-of-life symptoms, and the aftermath of bereavement, there is no question that cancer-induced suffering is great and that there is a major need for research in cancer palliative care to relieve this suffering. Dr. Jatoi is a mid-career investigator who is re-submitting a K24 application entitled, "Mentoring and Research in Cancer Palliative Care." Her career goals are as follows: 1) To conduct rigorous, clinical and translational research in cancer palliative care with the short-term goal of relieving suffering among cancer patients; 2) To provide opportunities for career growth in cancer palliative care for a diverse group of young investigators with the long-term goal of, again, relieving suffering among cancer patients. Dr. Jatoi is well suited to meet these career goals. She has conducted multiple clinical and translational studies on cancer palliative care, thus generating over 120 published manuscripts. These studies have focused largely on palliating cancer-associated anorexia and weight loss, but they have also, at times, focused on the management of other cancer-related symptoms. As a mentor and senior author, Dr. Jatoi has published 28 manuscripts with 16 young investigators from highly diverse backgrounds. Finally, the Mayo Clinic Comprehensive Cancer Center holds an unwavering commitment to patient care, a vast clinical trial infrastructure, comprehensive laboratory resources, and a dynamic, highly collaborative environment- thus, further ensuring the success of this application.

描述(由申请人提供)：去年，大约140万美国人被诊断出患有癌症，大约56万人死于癌症。当人们考虑到与癌症治疗相关的不良事件、临终症状的广泛和严重程度以及丧失亲人的后果时，毫无疑问，癌症引起的痛苦是巨大的，迫切需要研究癌症姑息治疗来缓解这种痛苦。 贾托博士是一名职业生涯中期的研究人员，他正在重新提交一份K24申请，标题为《癌症姑息治疗中的指导和研究》。她的职业目标如下：1)在癌症姑息治疗方面进行严谨的临床和转化性研究，短期目标是减轻癌症患者的痛苦；2)为不同的年轻研究人员提供癌症姑息治疗方面的职业发展机会，长期目标再次是减轻癌症患者的痛苦。 贾托博士非常适合实现这些职业目标。她进行了多项关于癌症姑息治疗的临床和翻译研究，从而产生了120多篇已发表的手稿。这些研究主要集中在缓解癌症相关的厌食症和减肥上，但有时也关注其他癌症相关症状的处理。作为导师和资深作者，贾托博士与来自不同背景的16名年轻研究人员一起发表了28篇手稿。最后，梅奥诊所综合癌症中心坚定不移地致力于患者护理、庞大的临床试验基础设施、全面的实验室资源以及动态、高度协作的环境-因此，进一步确保了这一应用的成功。

项目成果

A systematic compilation of reports published on opioid-related problems.

关于阿片类药物相关问题的报告的系统汇编。

• DOI: 10.5055/jom.2011.0047
• 发表时间: 2011
• 期刊: Journal of opioid management
• 作者: Butts,Matthew;Jatoi,Aminah
• 通讯作者: Jatoi,Aminah

Bevacizumab-induced nasal septal perforation: incidence of symptomatic, confirmed event(s) in colorectal cancer patients.

• DOI: 10.3109/0284186x.2010.537692
• 发表时间: 2011-05
• 期刊: Acta oncologica (Stockholm, Sweden)
• 作者: Ramiscal JA;Jatoi A
• 通讯作者: Jatoi A

Bone pain from granulocyte colony stimulating factor: does clinical trial sponsorship by a pharmaceutical company influence its reporting?

粒细胞集落刺激因子引起的骨痛：制药公司赞助的临床试验是否会影响其报告？

• DOI: 10.1111/j.1365-2354.2009.01136.x
• 发表时间: 2011
• 期刊: European journal of cancer care
• 影响因子: 2.1
• 作者: Aldairy,Y;Nguyen,PL;Jatoi,A
• 通讯作者: Jatoi,A

Parenteral nutrition in patients with advanced cancer: merging perspectives from the patient and healthcare provider.

晚期癌症患者的肠外营养：患者和医疗保健提供者的观点融合。

• DOI: 10.1053/j.seminoncol.2011.03.020
• 发表时间: 2011
• 期刊: Seminars in oncology
• 影响因子: 4
• 作者: Mitchell,Jessica;Jatoi,Aminah
• 通讯作者: Jatoi,Aminah

Self-perceptions of age among 292 chemotherapy-treated cancer patients: Exploring associations with symptoms and survival.

292 名接受化疗的癌症患者对年龄的自我认知：探索与症状和生存的关联。

• DOI: 10.1016/j.jgo.2013.02.001
• 发表时间: 2013
• 期刊: Journal of geriatric oncology
• 影响因子: 3
• 作者: Lim,MingY;Stephens,ElisabethK;Novotny,Paul;Price,Katharine;Salayi,Marcia;Roeker,Lindsey;Peethambaram,Prema;Jatoi,Aminah
• 通讯作者: Jatoi,Aminah