Older Sexual and Gender Minority Patients with Serious Illness: Program-Building to Identify and Address Needs

患有严重疾病的老年性和性别少数患者：建立项目以确定和满足需求

• 批准号: 10684915
• 负责人: Aminah Jatoi
• 金额: $ 14.91万
• 依托单位: MAYO CLINIC ROCHESTER
• 依托单位国家: 美国
• 财政年份: 2022
• 资助国家: 美国
• 起止时间: 2022-09-01 至 2027-05-31
• 项目状态: 未结题
• 来源: https://reporter.nih.gov/project-details/10684915
• 关键词: Address; Advisory Committees; Advocate; Age Years; Aging; Anxiety; Applications Grants; Award; Caring; Cessation of life; Child; Clinic; Clinical; Clinical Sciences; Comprehensive Cancer Center; Data; Development; Diagnosis; Discrimination; Disease; Disparity; Do Not Resuscitate Order; Educational Curriculum; Elderly; Environment; Face; Family; Funding; General Population; Goals; Grant; Health Personnel; Healthcare; Home; Individual; Infrastructure; Inpatients; Institution; International; Intersex; Interview; Leadership; Learning; Lesbian Gay Bisexual; Lesbian Gay Bisexual Transgender; Loneliness; Malignant Neoplasms; Mayo Clinic Cancer Center; Medical Electronics; Medical Staff; Medicare; Mental Depression; Mental Health; Mentors; Methodology; Minnesota; Needs Assessment; Oncologist; Outcome; Palliative Care; Participant; Pastoral Care; Patient Self-Report; Patients; Persons; Physicians; Pilot Projects; Positioning Attribute; Principal Investigator; Program Development; Psychosocial Influences; Publications; Religion; Religiosity; Request for Applications; Research; Research Personnel; Research Proposals; Resources; Review Literature; Risk; Same-sex; Series; Sexual and Gender Minorities; Social support; Surveys; Symptoms; Translational Research; Underserved Population; United States National Institutes of Health; Visit; asexual; cancer therapy; career; career development; clinical center; course development; data centers; end of life; experience; family structure; gender minority group; human old age (65+); improved; interest; intersectionality; lectures; minority patient; multidisciplinary; novel; older patient; palliation; preference; professor; programs; psychosocial; queer; recruit; sexual minority men; sexual minority women; social; social media; statistics; symposium; symptomatology; transgender; two spirit

This NIA K07 Academic Leadership Career Award resubmission entitled, “Older Sexual and Gender Minority Patients with Serious Illness: Program-Building to Identity and Address Needs,” seeks to help these understudied and underserved groups of patients, who, in the face of advanced age and serious illness, are more likely to be single, living alone, without children, lacking in social support, and at risk for and fearful of discrimination. The applicant is a senior physician at Mayo Clinic and has a long track record of research in studying symptoms and psychosocial issues in ill patients (400+ publications), mentoring (50+ mentees + principal investigator/program director of career development program K12CA090628-20), and serving as a leader in both her home institution and nationally. This track record and these experiences are brought to this application with the goal of understanding and addressing the unmet needs of these groups of older sexual and gender minority (SGM) patients – defined by the NIH as “individuals who identify as lesbian, gay, bisexual, transgender, two-spirit, queer, and/or intersex.” A uniquely rich institutional environment that includes the Kogod Center on Aging; the Mayo Clinic Cancer Center (an NCI-designated comprehensive cancer center); a robust Center for Clinical and Translational Science (CCATS); a nationally renowned statistics and data center; the robust Mayo Clinic practice, which provides depth and breadth of clinical expertise in the management of a vast array of serious illnesses to over 1 million patients per year; and, last but not least, the 120,000+ (and growing) social media platform, Mayo Clinic Connect -- perhaps the largest such patient-centric electronic medical resource in the world -- will set the stage for the development of this programmatic infrastructure. Novel, ground-breaking research early in the grant-cycle will consist of a needs-assessment that uses both qualitative and quantitative methodology to learn the unremitting symptomatology and unrelieved psychosocial hardships of these older patients and that relies on Mayo Clinic Connect (an estimated 30% of users self-report as 65+ years of age) to reach older SGM patients anonymously and to learn confidentially about their concerns. This needs assessment will give rise to a series of annual requests for pilot grant applications aimed at young investigators. Young investigators who are awarded a pilot project will acquire mentoring from the applicant, engage in coursework, participate in a weekly seminar series, learn from a biannual visiting professor series, begin to learn to contribute to CCATS course development on older SGM patients, and further launch their careers as investigators in this field. National/international experts in their respective fields and a patient advocate will serve on an advisory committee, providing programmatic guidance over the 5-year grant cycle. These efforts are destined to establish a sustainable, funded research program to improve the lives of older SGM patients with serious illness.

本 NIA K07 学术领导职业奖重新提交的标题为“老年性和性别少数群体” 患有严重疾病的患者：建立项目以识别和满足需求”，旨在帮助这些患者 未得到充分研究和服务的患者群体，他们面对高龄和严重疾病， 更有可能是单身、独居、没有孩子、缺乏社会支持、面临风险和害怕 歧视。申请人是梅奥诊所的高级医师，在以下领域拥有长期的研究记录 研究病人的症状和社会心理问题（400 多篇出版物），指导（50 多名受指导者 + 职业发展项目 K12CA090628-20 的首席研究员/项目主任），并担任 在她所在机构和全国范围内都是领导者。这些记录和这些经验都被带到了这里 旨在了解和解决这些老年性群体未满足的需求的应用 和性别少数 (SGM) 患者——美国国立卫生研究院 (NIH) 将其定义为“自认为是女同性恋、男同性恋、双性恋、 跨性别者、双重精神、酷儿和/或双性人。”独特而丰富的制度环境，包括 科戈德老龄化中心；梅奥诊所癌症中心（NCI 指定的综合癌症中心）；一个 强大的临床和转化科学中心（CCATS）；全国知名的统计数据中心； 梅奥诊所 (Mayo Clinic) 的强大实践，为管理患者提供了深度和广度的临床专业知识 每年有超过 100 万名患者患有各种严重疾病；最后但并非最不重要的一点是，超过 120,000（以及 不断增长的）社交媒体平台，Mayo Clinic Connect——也许是最大的此类以患者为中心的电子平台 世界各地的医疗资源——将为这一规划性基础设施的发展奠定基础。 拨款周期早期的新颖、突破性研究将包括使用两者的需求评估 定性和定量的方法来了解持续的症状和未缓解的心理社会 这些老年患者的困难依赖于 Mayo Clinic Connect（估计 30% 的用户自我报告 65 岁以上）匿名接触老年 SGM 患者并秘密了解他们的情况 的担忧。该需求评估将引发一系列年度试点拨款申请 针对年轻研究者。获得试点项目的年轻研究人员将获得来自以下机构的指导 申请人，参与课程作业，参加每周的研讨会系列，从一年两次的访问中学习 教授系列，开始学习为老年 SGM 患者的 CCATS 课程开发做出贡献，以及 进一步开启他们作为该领域研究人员的职业生涯。各自领域的国内/国际专家 患者权益倡导者将在咨询委员会中任职，提供为期 5 年的规划指导 拨款周期。这些努力注定要建立一个可持续的、受资助的研究计划，以改善 患有严重疾病的老年 SGM 患者的生活。

项目成果

Understanding Disparities: A Case Illustrative of the Struggles Facing Transgender and Gender Diverse Patients With Cancer.

了解差异：一个案例说明跨性别和性别多样化癌症患者面临的斗争。

• DOI: 10.6004/jnccn.2023.7005
• 发表时间: 2023
• 期刊: Journal of the National Comprehensive Cancer Network : JNCCN
• 作者: Cathcart-Rake,ElizabethJ;Kling,JulianaM;Carroll,EvelynF;Davidge-Pitts,Caroline;Le-Rademacher,Jennifer;Ridgeway,JenniferL;Gonzalez,CesarA;Jatoi,Aminah
• 通讯作者: Jatoi,Aminah