AANCART: The National Center for Reducing Asian American Cancer Health Disparitie

描述（由申请人提供）：为了回应 RFA-CA-09-032，亚裔美国人癌症意识、研究和培训网络 (AANCART) 提议建立国家减少亚裔美国人癌症健康差异中心，名为 AANCART：国家中心。该中心由学术界和社区首席研究员领导，将采用基于社区的参与性研究 (CBPR) 方法来实现其具体目标： 1) 建立一个国家中心，以 AANCART 在过去 9 年中作为 NCI 资助的社区网络计划创建的社区学术伙伴关系网络为基础，开展外展、研究和培训，该计划已取得许多重大成就并在社区中建立了信任； 2) 深入社区，减少亚裔美国人的癌症差异和相关共病； 3）开展、促进和传播循证干预研究，以减少亚裔美国人面临的不必要的癌症负担； 4) 培训和培育新的早期 CBPR 研究人员，以提交同行评审的提案并获得资金来开展研究，以减少健康差异。该 U54 申请显示： 1) 该中心的行政组织方式； 2） 如何通过创建和增加获得适合文化、特定语言和循证材料的机会，在加利福尼亚州和夏威夷的 4 个亚裔美国人群体中实施外展计划，这些材料旨在增加有关癌症的知识和有益预防措施的使用； 3) 为期 5 年的全面研究项目将如何开发、实施、评估和传播一项整群随机对照试验的结果，该试验旨在评估非专业健康教育者在 4 个地区（檀香山、洛杉矶、萨克拉门托和旧金山）的 4 个亚裔美国人群体（菲律宾人、苗族、韩国人和越南人）中促进结直肠癌筛查的有效性，以及为期 2 年的试点研究项目将如何评估华裔美国人对生物样本收集的认知和文化观点； 4) 培训计划如何通过结合个性化指导计划、预定研讨会以及与 NIH 临床和转化科学奖相关的课程来培养新的早期研究人员。

DESCRIPTION (provided by applicant): In response to RFA-CA-09-032, the Asian American Network for Cancer Awareness, Research, and Training (AANCART) proposes to create the National Center for Reducing Asian American Cancer Health Disparities entitled AANCART: The National Center. This Center, led by academic and community Principal investigators, will use a community-based participatory research (CBPR) approach to achieve its Specific Aims: 1) Build a National Center to conduct outreach, research, and training based on the network of community-academic partnerships created by AANCART in the preceding 9 years as an NCI-funded Community Network Program, which has generated many significant accomplishments and established trust in the community; 2) Outreach to communities to reduce cancer disparities and related co-morbid conditions among Asian Americans; 3) Conduct, foster, and disseminate evidence-based intervention Research to reduce the unnecessary cancer burden confronting Asian Americans; 4) Train and nurture new and early stage CBPR investigators to submit peer-reviewed proposals and obtain funding to conduct research to reduce health disparities. This U54 application shows: 1) How the Center is administratively organized; 2) How the Outreach Program will be implemented among 4 Asian American populations in California and Hawaii by creating and increasing access to culturally appropriate, linguistically-specific, and evidence-based materials designed to increase knowledge about cancer and the use of beneficial preventive procedures; 3) How a 5-year Full Research Project will develop, implement, evaluate, and disseminate the results of a cluster randomized controlled trial of the efficacy of lay health educators to promote colorectal cancer screening among 4 Asian American groups (Filipinos, Hmong, Korean, and Vietnamese) in 4 regions (Honolulu, Los Angeles, Sacramento, & San Francisco) and how a 2-year Pilot Research Project will assess cognitive & cultural perspectives among Chinese Americans regarding biospecimen collection; and 4) How a Training Program will develop new and early stage investigators by combining individualized mentoring plans, scheduled seminars, and a curriculum linked to the NIH Clinical & Translational Science Awards.