Translational Research Skills Development Core (TRSDC): Training Future Generati

转化研究技能发展核心（TRSDC）：培训未来一代

• 批准号: 8469095
• 负责人: Richard Clinton Becker
• 金额: $ 14.83万
• 依托单位: DUKE UNIVERSITY
• 依托单位国家: 美国
• 资助国家: 美国
• 起止时间: 至
• 项目状态: 未结题
• 来源: https://reporter.nih.gov/project-details/8469095
• 关键词: Address; Adopted; Award; Basic Science; Clinical; Clinical Research; Communities; Conflict (Psychology); Development; Disease; Education; Environment; Evaluation; Evolution; Faculty; Feedback; Fostering; Funding; Funding Mechanisms; Future; Grant; Hemostatic Agents; Immersion Investigative Technique; Individual; Industry; Institution; Knowledge; Laws; Leadership; Learning; Marketing; Medical; Mentors; Metric; Outcome; Participant; Philosophy; Policies; Positioning Attribute; Process; Research; Research Personnel; Research Project Grants; Research Training; Resources; Science; Scientist; Secure; Students; Training; Training Programs; Training and Education; Translating; Translational Research; United States National Institutes of Health; Vision; Work; Writing; base; bench to bedside; career; career development; drug discovery; interest; investigator training; meetings; pressure; programs; skills; statistics; success; trend

Traditional graduate and medical programs provide researchers with program-specific background, training, and scientific expertise, but they fail to provide students with the breadth of knowledge and interdisciplinary understanding required to successfully translate basic science discoveries into clinical outcomes. Translational investigators trained within these programs have historically overcome this by engaging in "team science" to assemble the scientific expertise needed for a translational project. Inspired by changing trends in the conduct of biomedical science research, and in efforts to encourage young faculty to participate in translational team projects, the NIH revised its criteria for faculty tenure to acknowledge the importance and contributions of team science in 2006. Despite this adaptation, many individual institutions have been slow to adopt these policies and thus young faculty are often conflicted due to contradictions between the metrics of success in team science and those by which they are evaluated in the traditional academic tenure career path. To complicate the matter, recent U.S. labor statistics indicate that while the number of PhDs granted over the past 10 years has doubled in the biomedical fields, the number of tenure-based faculty positions has remained constant. This concerning trend is further exacerbated by recent layoffs in industry-based drug discovery departments and decreases in federal and state funding. Inevitably, the simple laws of supply and demand are making it more competitive (and difficult) to secure and maintain academic tenure positions. The culmination of these contradictions and pressures is negatively impacting translational research in the academic environment. The DTMI-CTHD believes that the broad spectrum training delineated herein would better prepare translational scientists to compete in the current market, foster successful academic research careers, and ultimately allow participants to facilitate translational research and contribute to the translational research community in a variety of capacities.

传统的研究生和医学课程为研究人员提供了特定于课程的背景、培训和科学专业知识，但它们未能为学生提供成功将基础科学发现转化为临床成果所需的知识广度和跨学科理解。在这些项目中培训的翻译研究人员历史上通过参与“团队科学”来克服这一点，以汇集翻译项目所需的科学专业知识。受到生物医学科学研究不断变化的趋势的启发，并努力鼓励年轻教师参与翻译团队项目，NIH修订了教师任期标准，以承认团队的重要性和贡献。 2006年科学。尽管这种适应，许多个别机构一直缓慢地采取这些政策，因此年轻的教师往往是冲突，由于团队科学的成功和那些他们在传统的学术终身职位的职业道路进行评估的指标之间的矛盾。 更复杂的是，最近的美国劳工统计数据表明，虽然过去10年中生物医学领域获得的博士学位数量翻了一番，但终身教职的数量保持不变。这种令人担忧的趋势进一步加剧了最近裁员的行业为基础的药物发现部门和减少联邦和国家的资金。不可避免的是，简单的供求法则使得获得和维持学术终身职位变得更具竞争力（也更困难）。 这些矛盾和压力的顶峰正在对学术环境中的翻译研究产生负面影响。DTMI-CTHD认为，本文描述的广谱培训将更好地为翻译科学家在当前市场中的竞争做好准备，促进成功的学术研究事业，并最终使参与者能够促进翻译研究并以各种能力为翻译研究社区做出贡献。