Integrated approaches to targeting G protein-coupled receptors: Translational studies of novel drug-receptor paradigms
Integrated approaches to targeting G protein-coupled receptors: Translational studies of novel drug-receptor paradigms
批准号:
nhmrc : 1102950
负责人:
Prof Arthur Christopoulos
金额:
$58.74万
依托单位:
依托单位国家:
澳大利亚
项目类别:
Research Fellowships
财政年份:
2016
资助国家:
澳大利亚
项目状态:
已结题
起止时间:
2016-01-01 至 2020-12-31
中文摘要
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英文摘要
This Fellowship focuses on one of the largest family of proteins found in the human body, the so-called ‘G protein-coupled receptors ‘ (GPCRs). GPCRs control how each of our cells communicates with one another, and have been implicated in virtually all diseases. This proposal will study new mechanisms of targeting drugs to GPCRs that can overcome current drug discovery bottlenecks and lead to new ways of treating neuropsychiatric, cardiovascular, inflammatory and metabolic diseases.
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会议论文
Translating membrane proteins into therapeutics; from bedside to bench
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批准号:nhmrc : 1150083
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项目类别:Program Grants
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资助金额:$631.19万
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财政年份:2019
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负责人:Prof Arthur Christopoulos
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依托单位:
Translating membrane proteins into therapeutics; from bedside to bench
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批准号:nhmrc : GNT1150083
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项目类别:Programs
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资助金额:$946.6万
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财政年份:2019
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负责人:Prof Arthur Christopoulos
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依托单位:
Integrated approaches to targeting G protein-coupled receptors: Translational studies of novel drug-receptor paradigms
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批准号:nhmrc : GNT1102950
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项目类别:Research Fellowships
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资助金额:$85.2万
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财政年份:2016
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负责人:Prof Arthur Christopoulos
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依托单位:
The Janus Faces of G Protein-Coupled Receptors: Implications for Disease Mechanisms and Opportunities for Drug Discovery
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批准号:nhmrc : 1055134
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项目类别:Program Grants
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资助金额:$531.41万
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财政年份:2014
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负责人:Prof Arthur Christopoulos
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依托单位:
Understanding the major class of cell surface drug targets
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批准号:nhmrc : GNT1055134
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项目类别:Programs
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资助金额:$759.58万
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财政年份:2014
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负责人:Prof Arthur Christopoulos
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依托单位:
Research Fellowship: Understanding G protein-coupled receptors (GPCRs)
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批准号:nhmrc : 1041875
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项目类别:Research Fellowships
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资助金额:$29.62万
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财政年份:2013
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负责人:Prof Arthur Christopoulos
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依托单位:
Understanding G Protein-Coupled Receptors (GPCRs): Accelerating Discovery from Concept to Clinic.
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批准号:nhmrc : 519461
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项目类别:Programs
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资助金额:$458.21万
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财政年份:2009
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负责人:Prof Arthur Christopoulos
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依托单位:
Novel modes of regulating serotonin 5HT2c receptors.
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批准号:nhmrc : 400133
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项目类别:NHMRC Project Grants
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资助金额:$30.49万
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财政年份:2006
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负责人:Prof Arthur Christopoulos
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依托单位:
Novel modes of signalling of serotonin 5-HT2c receptors.
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批准号:LP0562257
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项目类别:Linkage Projects
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资助金额:$7.0万
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财政年份:2006
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负责人:Prof Arthur Christopoulos
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依托单位:
Allosteric Modulation of G Protein-Coupled Receptors
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批准号:nhmrc : 251538
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项目类别:NHMRC Project Grants
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资助金额:$24.2万
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财政年份:2003
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负责人:Prof Arthur Christopoulos
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依托单位:
pharmacology of central nervous system disorders such as schitzophrenia, dementia and chronic pain
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批准号:nhmrc : 251532
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项目类别:NHMRC Research Fellowships
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资助金额:$36.72万
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财政年份:2003
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负责人:Prof Arthur Christopoulos
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依托单位:
Molecular Mechanisms of G Protein-Coupled Receptor Cross Talk
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批准号:nhmrc : 209083
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项目类别:NHMRC Project Grants
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资助金额:$17.14万
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财政年份:2002
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负责人:Prof Arthur Christopoulos
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依托单位:
国内基金
海外基金
Lagrangian origin of geometric approaches to scattering amplitudes
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批准号:24ZR1450600
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项目类别:省市级项目
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资助金额:--
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批准年份:2024
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负责人:ALEXANDER OCHIROV
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依托单位: