The Chemistry-Biology Interface Program at Johns Hopkins University

约翰·霍普金斯大学化学-生物界面项目

• 批准号: 8690096
• 负责人: STEVEN E ROKITA
• 金额: $ 22.57万
• 依托单位: JOHNS HOPKINS UNIVERSITY
• 依托单位国家: 美国
• 财政年份: 2008
• 资助国家: 美国
• 起止时间: 2008-07-01 至 2018-06-30
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/8690096
• 关键词: Biology; Chemistry; Universities; programs

DESCRIPTION (provided by applicant): This proposal seeks to renew support for a training program at the Chemistry-Biology Interface (CBI) at Johns Hopkins University that was established in 2005 and received NIH support in 2008. The goal is to train predoctoral students to carry out biomedical research using the tools of Chemistry and Biology. The Program is a collaborative effort between faculty in the Departments of Biochemistry and Molecular Biology (Bloomberg School of Public Health), Pharmacology and Molecular Sciences (School of Medicine), Biophysics and Biophysical Chemistry (School of Medicine), and Chemical and Biomolecular Engineering (Whiting School of Engineering), with their colleagues in the Biology, Biophysics, and Chemistry Departments (Zanvyl Krieger School of Arts & Sciences). Student participants have a diverse array of research projects including synthesis, mechanism, enzymology, molecular imaging, and biomacromolecular structure to choose from in 32 research groups. The students receive coursework training in the biological and chemical sciences, including a two-semester course in Chemical Biology designed especially for the Program, but open to all Johns Hopkins University students. Other aspects of the CBI Program include CBI Forum where students present original research proposals, research updates, first year research rotation results, and defend their theses, as well as an Annual Retreat. The students are immersed in a common curriculum (independent of the Department in which their research advisors hold primary appointments), apply directly to the CBI Program, and receive a Ph.D. in Chemical Biology upon completion. The CBI Program was initiated in fall 2005 using funding from the University, which continues to provide a high level of support. NIH currently provides one year of support for 5 students. Support is requested for 6 graduate students. An extensive network of support in the form of advising and mentoring is in place to maximize the students' success. This has resulted in >92% retention of students since the program began in 2005.

描述（由申请人提供）：本提案旨在重新支持约翰霍普金斯大学化学-生物学界面（CBI）的培训计划，该计划成立于2005年，并于2008年获得NIH的支持。目标是培养博士生利用化学和生物学的工具进行生物医学研究。该项目是生物化学和分子生物学（布隆伯格公共卫生学院）、药理学和分子科学（医学院）、生物物理和生物物理化学（医学院）、化学和生物分子工程（怀廷工程学院）的教师与他们在生物学、生物物理学和化学系（Zanvyl Krieger艺术与科学学院）的同事共同努力的结果。学生参与者在32个研究小组中有各种各样的研究项目，包括合成，机制，酶学，分子成像和生物大分子结构。学生们接受生物和化学科学方面的课程训练，包括专门为该项目设计的两个学期的化学生物学课程，但对所有约翰霍普金斯大学的学生开放。CBI项目的其他方面包括CBI论坛，学生在论坛上展示原创研究建议、研究更新、第一年的研究轮换结果，并为他们的论文辩护，以及年度静修。学生们沉浸在共同的课程中（独立于他们的研究顾问担任主要任命的部门），直接申请CBI计划，并在完成后获得化学生物学博士学位。CBI项目于2005年秋季启动，由大学提供资金，继续提供高水平的支持。NIH目前为5名学生提供一年的支持。申请资助6名研究生。以建议和指导的形式提供广泛的支持网络，以最大限度地提高学生的成功。自2005年该项目开始以来，这使得学生的保留率达到了50%。