The Influence of Hospital Variability on the Management of Cancer-Associated Comp

医院变异性对癌症相关补偿管理的影响

基本信息

  • 批准号:
    8457724
  • 负责人:
  • 金额:
    $ 33.2万
  • 依托单位:
  • 依托单位国家:
    美国
  • 项目类别:
  • 财政年份:
    2013
  • 资助国家:
    美国
  • 起止时间:
    2013-01-01 至 2017-12-31
  • 项目状态:
    已结题

项目摘要

DESCRIPTION (provided by applicant): The quality of treatment for cancer-associated complications, those complications directly attributable to the cancer itself or that result from chemotherapy and/or radiation, have received little attention. This is particularly problematic as cancer-associated complications are associated with significant morbidity, are often accompanied by pain and discomfort, and require the expenditure of substantial healthcare resources for treatment. The management of cancer-associated complications is compounded by the availability of a myriad of treatment options, many of which are unproven and associated with significant cost. Little is known about the factors that influence allocation of care for thes complications and what factors influence outcome. The health care a patient receives and its associated outcomes are influenced by the interplay of a number of patient, physician, and hospital factors. For acute inpatient medical conditions the characteristics of the hospital in which a patient is treated play a crucial role. There is growing recognition that there is widespread between-hospital variation in how care is allocated and that these differences in practice patterns explain a large portion of treatment variability. Uninsured and minority patients are particularly vulnerable to these hospital level disparities as these patients are disproportionately more likely to receive care at facilities with limited clinical and financial resources that may adversely affect quality. In this proposal we will determine the quality of treatment for hospitalized patients admitted with a primary diagnosis of: febrile neutropenia, hypercalcemia of malignancy, esophagitis, and acute cancer-associated pain. For each cancer-associated complication we will determine patterns of treatment, the factors that underlie treatment decisions, and the effect of prompt initiation of guideline-based therapy on outcomes. For each condition we will first examine the utilization of guideline-based and non-indicated treatments. We will then comprehensively examine the influence of patient, physician, and hospital characteristics as well as between- hospital variations on the allocation of guideline-based care. We hypothesize that there is substantial variation in treatment between hospitals that is unexplained by traditional measures. Finally, we will perform novel causal inference and mediation analyses to determine the direct and indirect effects operating through a mediator of prompt guideline-based treatment on outcomes (length of stay, readmission, cost, non-routine discharge and mortality) for each complication. In addition to including a number of novel statistical methodologies, this proposal will utilize a unique database ideally suited to the study of these complications. The data from these studies will lead to immediately actionable results that can be used to guide the implementation pragmatic hospital-based interventions to improve the quality of care for patients with cancer-associated complications.
描述(由申请人提供):癌症相关并发症的治疗质量,那些直接归因于癌症本身或由化疗和/或放疗引起的并发症,很少受到关注。这尤其成问题,因为癌症相关并发症与显著发病率相关,通常伴有疼痛和不适,并且需要花费大量医疗资源进行治疗。癌症相关并发症的管理因无数治疗方案的可用性而复杂化,其中许多未经证实且费用高昂。对于影响这些并发症的护理分配的因素以及影响结果的因素知之甚少。患者接受的医疗保健及其相关结果受许多患者、医生和医院因素的相互作用影响。对于急性住院病人来说,治疗病人的医院的特点起着至关重要的作用。越来越多的人认识到,医院之间在如何分配护理方面存在广泛的差异,这些实践模式的差异解释了很大一部分治疗差异。没有保险和少数族裔患者

项目成果

期刊论文数量(0)
专著数量(0)
科研奖励数量(0)
会议论文数量(0)
专利数量(0)

数据更新时间:{{ journalArticles.updateTime }}

{{ item.title }}
{{ item.translation_title }}
  • DOI:
    {{ item.doi }}
  • 发表时间:
    {{ item.publish_year }}
  • 期刊:
  • 影响因子:
    {{ item.factor }}
  • 作者:
    {{ item.authors }}
  • 通讯作者:
    {{ item.author }}

数据更新时间:{{ journalArticles.updateTime }}

{{ item.title }}
  • 作者:
    {{ item.author }}

数据更新时间:{{ monograph.updateTime }}

{{ item.title }}
  • 作者:
    {{ item.author }}

数据更新时间:{{ sciAawards.updateTime }}

{{ item.title }}
  • 作者:
    {{ item.author }}

数据更新时间:{{ conferencePapers.updateTime }}

{{ item.title }}
  • 作者:
    {{ item.author }}

数据更新时间:{{ patent.updateTime }}

Jason Wright其他文献

Jason Wright的其他文献

{{ item.title }}
{{ item.translation_title }}
  • DOI:
    {{ item.doi }}
  • 发表时间:
    {{ item.publish_year }}
  • 期刊:
  • 影响因子:
    {{ item.factor }}
  • 作者:
    {{ item.authors }}
  • 通讯作者:
    {{ item.author }}

{{ truncateString('Jason Wright', 18)}}的其他基金

Racial Disparity in Diagnostic Evaluation of Uterine Cancer
子宫癌诊断评估中的种族差异
  • 批准号:
    10276384
  • 财政年份:
    2021
  • 资助金额:
    $ 33.2万
  • 项目类别:
Racial Disparity in Diagnostic Evaluation of Uterine Cancer
子宫癌诊断评估中的种族差异
  • 批准号:
    10888758
  • 财政年份:
    2021
  • 资助金额:
    $ 33.2万
  • 项目类别:
Racial Disparity in Diagnostic Evaluation of Uterine Cancer
子宫癌诊断评估中的种族差异
  • 批准号:
    10610935
  • 财政年份:
    2021
  • 资助金额:
    $ 33.2万
  • 项目类别:
The Influence of Hospital Variability on the Management of Cancer-Associated Comp
医院变异性对癌症相关补偿管理的影响
  • 批准号:
    8601054
  • 财政年份:
    2013
  • 资助金额:
    $ 33.2万
  • 项目类别:
The Influence of Hospital Variability on the Management of Cancer-Associated Comp
医院变异性对癌症相关补偿管理的影响
  • 批准号:
    8976833
  • 财政年份:
    2013
  • 资助金额:
    $ 33.2万
  • 项目类别:
The Influence of Hospital Variability on the Management of Cancer-Associated Comp
医院变异性对癌症相关补偿管理的影响
  • 批准号:
    8804245
  • 财政年份:
    2013
  • 资助金额:
    $ 33.2万
  • 项目类别:

相似海外基金

Understanding early causal pathways in ADHD: can early-emerging atypicalities in activity and affect cause later-emerging difficulties in attention?
了解 ADHD 的早期因果路径:早期出现的活动和影响的非典型性是否会导致后来出现的注意力困难?
  • 批准号:
    MR/X021998/1
  • 财政年份:
    2023
  • 资助金额:
    $ 33.2万
  • 项目类别:
    Research Grant
Predictive information and cognitive process: How affect the emotional value of pre-cue on the attention control process
预测信息与认知过程:预提示的情感价值如何影响注意控制过程
  • 批准号:
    22K03209
  • 财政年份:
    2022
  • 资助金额:
    $ 33.2万
  • 项目类别:
    Grant-in-Aid for Scientific Research (C)
Visuocortical Dynamics of Affect-Biased Attention in the Development of Adolescent Depression
青少年抑郁症发展过程中情感偏向注意力的视觉皮层动力学
  • 批准号:
    10380686
  • 财政年份:
    2019
  • 资助金额:
    $ 33.2万
  • 项目类别:
Spatial and Temporal Mechanisms of Affect-Biased Attention
情感偏向注意力的时空机制
  • 批准号:
    RGPIN-2014-04202
  • 财政年份:
    2019
  • 资助金额:
    $ 33.2万
  • 项目类别:
    Discovery Grants Program - Individual
Visuocortical Dynamics of Affect-Biased Attention in the Development of Adolescent Depression
青少年抑郁症发展过程中情感偏向注意力的视觉皮层动力学
  • 批准号:
    9888437
  • 财政年份:
    2019
  • 资助金额:
    $ 33.2万
  • 项目类别:
Visuocortical Dynamics of Affect-Biased Attention in the Development of Adolescent Depression
青少年抑郁症发展过程中情感偏向注意力的视觉皮层动力学
  • 批准号:
    10597082
  • 财政年份:
    2019
  • 资助金额:
    $ 33.2万
  • 项目类别:
Spatial and Temporal Mechanisms of Affect-Biased Attention
情感偏向注意力的时空机制
  • 批准号:
    RGPIN-2014-04202
  • 财政年份:
    2018
  • 资助金额:
    $ 33.2万
  • 项目类别:
    Discovery Grants Program - Individual
Spatial and Temporal Mechanisms of Affect-Biased Attention
情感偏向注意力的时空机制
  • 批准号:
    RGPIN-2014-04202
  • 财政年份:
    2017
  • 资助金额:
    $ 33.2万
  • 项目类别:
    Discovery Grants Program - Individual
Emerging relations between attention and negative affect in the first two years of life
生命头两年注意力与负面情绪之间的新关系
  • 批准号:
    9673285
  • 财政年份:
    2016
  • 资助金额:
    $ 33.2万
  • 项目类别:
Spatial and Temporal Mechanisms of Affect-Biased Attention
情感偏向注意力的时空机制
  • 批准号:
    RGPIN-2014-04202
  • 财政年份:
    2016
  • 资助金额:
    $ 33.2万
  • 项目类别:
    Discovery Grants Program - Individual
{{ showInfoDetail.title }}

作者:{{ showInfoDetail.author }}

知道了