MIT Center for Environmental Health Sciences

在我们重新提交续签申请的过程中，我们请求提供资金，以继续支持NIEHS 麻省理工学院环境健康科学中心(CEHS)。这个 麻省理工学院CEHS的总体重点是了解有毒环境因子如何扰乱生物系统 并确定这种扰动可能如何影响人类健康。麻省理工学院CEHS由教授领导 利昂娜·萨姆森。目前的CEHS成员包括36名成员，来自麻省理工学院的8名成员 理工学院的系，再加上哈佛大学的三名成员， 特别是哈佛大学公共卫生学院(HSPH)和哈佛医学院(HMS)。麻省理工学院 生物、化学、生物工程、化学工程、土木工程和环境等系 工程、机械工程、核科学与工程、电气工程和 计算机科学；HSPH系是流行病学系，HMS系设在布里格姆大学 妇女医院和马萨诸塞州综合医院。目前的设施核心是：(I) 生物分析设施核心，(二)基因组学和成像设施核心，(三)动物模型设施 (四)综合健康科学设施核心。通过这四个设施提供的服务 核心包括复杂的质谱学，加速器质谱学，转录图谱， Solexa测序，生物信息学和机器人学，转基因和敲除动物生产，病理学 服务，最先进的显微镜和成像，以及临床转化性研究服务。其他 单位包括行政核心、试点项目方案、全球环境健康科学 计划，以及社区推广和教育核心(COEC)。该中心赞助各种不同的 丰富活动，包括生物工程系研讨会系列中的具体研讨会， 两个CEHS特定研讨会系列、一个年度海报会议和其他几个旨在 促进CEHS成员之间的互动，并促进CEHS在麻省理工学院的活动。

In this resubmission of our renewal application, funding is requested for continued support ofthe NIEHS Center for Environmental Health Sciences (CEHS) at the Massachusetts Institute of Technology (IVIIT). The overall focus ofthe MIT CEHS is to understand how toxic environmental agents perturb biological systems and to determine how such perturbations may affect human health. The MIT CEHS is led by Professor Leona Samson. The current CEHS membership consists of 36 members derived from a total of eight MIT departments in both the Schools of Science and Engineering, plus three members from Harvard University, specifically the Harvard School of Public Health (HSPH) and the Harvard Medical School (HMS). The MIT departments are Biology, Chemistry, Biological Engineering, Chemical Engineering, Civil and Environmental Engineering, Mechanical Engineering, Nuclear Science and Engineering, Electrical Engineering and Computer Science; the HSPH department is Epidemiology, and the HMS faculty are based at the Brigham and Women's Hospital and the Massachusetts General Hospital. The current Facilities Cores are (i) the Bioanalytical Facilities Core, (ii) the Genomics and Imaging Facilities Core, (iii) the Animal Models Facilities Core, (iv) the Integrative Health Sciences Facilities Core. The services available through the four Facilities Cores include sophisticated mass spectrometry, accelerator mass spectrometry, transcriptional profiling, Solexa sequencing, bioinformatics and robotics, transgenic and knock out animal production, pathology services, state-of-the-art microscopy and imaging, and clinical services for translational research. Other units include the Administrative Core, the Pilot Project Program, the Global Environmental Health Science Program, and the Community Outreach and Education Core (COEC). The Center sponsors a wide variety of enrichment activities including specific seminars in the Biological Engineering departmental seminar series, two CEHS specific seminar series, an annual Poster Session, and several other mechanisms designed to nurture interactions among CEHS members and to promote the activities ofthe CEHS at MIT.