Clinical Services Core

临床服务核心(CSC)是一个核心资源，旨在支持由Case CFAR发起或支持的所有人类主题研究项目的开发、实施和分析中的每一步。CSC的具体目标包括： ？维护和扩大全面和可访问的患者护理和研究数据库(PCRD)。 ？维护并扩展链接到患者护理数据库的标本储存库。 ？使研究人员能够接触到预先选定的感兴趣的患者，并(通过挖掘患者护理和研究数据库)确定有资格参加艾滋病毒临床试验或其他研究的患者。 ？维护、扩展和提供对新建立的数据库的访问，该数据库包括克利夫兰地区800多名艾滋病毒阴性志愿者，他们有兴趣参与艾滋病毒研究。 ？协调与参与旨在开展艾滋病毒观测数据研究的合作项目的其他机构交换临床和实验室数据。Case CFAR是两个此类合作的创始成员，这两个合作是CFAR综合临床系统网络(CNICs)和北美艾滋病队列研究和设计合作(NAACCORD)。 协助CFAR研究人员规划和设计使用PCRD和标本储存库的研究，帮助调查人员提出研究问题，充分利用核心提供的数据和标本。 ？向CFAR案件调查员提供生物统计学和流行病学方面的支持和建议，并提供流行病学和生物统计学方面的培训和师资发展。

The Clinical Services Core (CSC) is a central resource designed to support each step in the development, conduct, and analysis of all human subject research projects originated from or supported by the Case CFAR. Specific aims of the CSC include: ¿ Maintain and expand a comprehensive and accessible Patient Care and Research Database (PCRD). ¿ Maintain and expand a specimen repository linked to the patient care database. ¿ Provide researchers with access to patients pre-selected for interest and identified as eligible (through mining of the Patient Care and Research Database) to participate in HIV clinical trials or other research studies. ¿ Maintain, expand, and provide access to a newly established database of over 800 HIV-negative volunteers in the Cleveland area who are interested in participating in HIV research. ¿ Coordinate the exchange of clinical and laboratory data with other institutions participating in collaborative projects designed to conduct research on HIV observational data. The Case CFAR is a founding member of two such collaborations, the CFAR Network of Integrated Clinical Systems (CNICS) and the North American AIDS Cohort Collaboration on Research and Design (NAACCORD). ¿ Assist CFAR researchers in planning and designing studies that use the PCRD and the specimen repository by helping investigators formulate research questions that take full advantage of the data and specimens available through the Core. ¿ Provide biostatistical and epidemiologic support and advice to Case CFAR investigators, and provide training and faculty development in epidemiology and biostatistics.