Clinical Services Core D

临床服务核心 D

• 批准号: 9265762
• 负责人: BENIGNO RODRIGUEZ
• 金额: $ 19.01万
• 依托单位: CASE WESTERN RESERVE UNIVERSITY
• 依托单位国家: 美国
• 资助国家: 美国
• 起止时间: 至
• 项目状态: 未结题
• 来源: https://reporter.nih.gov/project-details/9265762
• 关键词: Acquired Immunodeficiency Syndrome; Alcohol consumption; American; Antiviral Agents; Area; Behavior assessment; Biometry; Biopsy; Cardiovascular system; Caring; Cells; Cerebrovascular Disorders; Clinical; Clinical Research; Clinical Sciences; Clinical Services; Clinical Trials; Collaborations; Collection; Computerized Medical Record; Data; Data Set; Databases; Development; Diabetes Mellitus; Diagnostic Imaging; Eligibility Determination; End stage renal failure; Enrollment; Epidemiology; Event; Funding; Goals; HIV; HIV Seropositivity; HIV vaccine; HIV/HCV; Health; Hepatitis A; Hepatitis C; Human Subject Research; Immunology; Individual; Inflammation; Institution; Laboratories; Leukapheresis; Link; Liver diseases; Malignant Neoplasms; Medical center; Mental Depression; Mining; Morbidity - disease rate; Ohio; Patient Care; Patients; Peripheral Blood Mononuclear Cell; Persons; Pharmaceutical Preparations; Plasma; Process; Provider; Recording of previous events; Records; Research; Research Design; Research Personnel; Research Project Grants; Research Support; Resources; Risk Assessment; Sampling; Services; Specimen; Substance abuse problem; Sudden Death; System; Teacher Professional Development; Training; Translational Research; Validation; cohort; data structure; design; flexibility; interest; lymph nodes; medication compliance; member; microbicide; mortality; novel; programs; quality assurance; repository; research study; translational study; vaccine development; volunteer

Project Summary Core D – Clinical Core The Clinical Services Core (CSC) is a central resource designed to support each step in the development, conduct, and analysis of all human subject research projects originated from or supported by the Case CFAR. Specific aims of the CSC include:  Maintain and expand a comprehensive and accessible Patient Care and Research Database (PCRD).  Maintain and expand a specimen repository linked to the patient care database.  Provide researchers with access to patients pre-selected for interest and identified as eligible (through mining of the Patient Care and Research Database) to participate in HIV clinical trials or other research studies.  Maintain, expand, and provide access to a newly established database of over 800 HIV-negative volunteers in the Cleveland area who are interested in participating in HIV research.  Coordinate the exchange of clinical and laboratory data with other institutions participating in collaborative projects designed to conduct research on HIV observational data. The Case CFAR is a founding member of two such collaborations, the CFAR Network of Integrated Clinical Systems (CNICS) and the North American AIDS Cohort Collaboration on Research and Design (NA- ACCORD).  Assist CFAR researchers in planning and designing studies that use the PCRD and the specimen repository by helping investigators formulate research questions that take full advantage of the data and specimens available through the Core.  Provide biostatistical and epidemiologic support and advice to Case CFAR investigators, and provide training and faculty development in epidemiology and biostatistics.

项目总结核心D -临床核心 临床服务核心（CSC）是一种中央资源，旨在支持 开发、实施和分析所有源自或支持的人类受试者研究项目 案例CFAR公务员制度委员会的具体目标包括： 维护和扩展一个全面和可访问的患者护理和研究数据库（PCRD）。 维护和扩展与患者护理数据库链接的样本库。 为研究人员提供预先选择的感兴趣的患者，并确定为合格（通过 患者护理和研究数据库的挖掘）参与HIV临床试验或其他 调查研究。 * 维持、扩大新建立的800多名艾滋病毒阴性者的数据库，并提供访问机会 克利夫兰地区有兴趣参与艾滋病研究的志愿者。 协调与其他参与机构的临床和实验室数据交换， 旨在对艾滋病毒观测数据进行研究的合作项目。案例CFAR是一个 两个这样的合作，CFAR网络的综合临床系统的创始成员 （CNICS）和北美艾滋病队列研究与设计合作组织（NA-AIDS Cohort Collaboration on Research and Design） 雅阁）。 协助CFAR研究人员规划和设计使用PCRD和标本的研究 通过帮助研究人员制定充分利用数据的研究问题， 和标本都可以通过核心获取 为病例CFAR调查人员提供生物统计学和流行病学支持和建议， 流行病学和生物统计学方面的培训和教师发展。