Multidisciplinary Rheumatology Training Program

描述（由申请人提供）：本提案是国家研究服务奖机构研究培训补助金（T32）的竞争性更新申请，以进一步支持约翰霍普金斯大学的多学科风湿病学培训计划。在过去的4年里，该项目在出版物、培训后任命教师职位以及获得独立、同行评审的资金方面取得了杰出的成就。我们证明了这个项目的总体发展轨迹仍然是非常积极的，为风湿病学博士后提供了优秀的部门和机构资源，项目师资队伍的持续增长和增强，以及一群极具竞争力的申请者（包括女性和代表性不足的少数民族）。该项目拥有非常敬业和高度专业的内部和外部咨询委员会，他们就项目的优先事项、系统和方向提供实时建议。该项目的教师成员具有广泛的兴趣和专业知识，并且在风湿病，免疫学，分子生物学和遗传学，细胞生物学，流行病学和生物统计学方面是经过验证的导师。该项目的总体目标是通过严格的研究方法指导和高质量的指导研究项目，每年培养2名博士后（共4个实习名额），成为风湿病领域的杰出学术研究者。我们的培训环境侧重于提供富有成效的临床和转化研究培训计划。b[1]为风湿病学博士后提供严格的研究方法培训，适用于临床和基础研究的开展；[2]利用卓越临床中心为明确定义的风湿病患者群体提供服务，使同类项目能够在已建立的患者群体中有效地进行；b[3]聘请博士后在国内知名教师的指导下进行高水平的重大课题研究；[4]对博士后进行多层次的指导，使其完成富有成效的研究，独立自主，发展成功的学术生涯；通过评估学术和项目成就的基准，包括同行评议的出版物、外部研究资金、培训后的学术地位和招募代表性不足的少数民族，评估并根据需要修改（通过纳入学员、培训项目教员以及内部和外部咨询委员会的反馈）这一培训环境的成果。

DESCRIPTION (provided by applicant): This proposal is a competitive renewal application for a National Research Service Award Institutional Research Training Grant (T32) to further support a Multidisciplinary Rheumatology Training Program at Johns Hopkins. Over the past 4 years, the program has demonstrated outstanding trainee achievement, in the areas of publications, appointment to faculty positions after training, and a very high rate of acquisition f independent, peer-reviewed funding. We demonstrate that the overall trajectory of this program remains steeply positive, with outstanding divisional and institutional resources available to postdoctoral fellows in rheumatology, continued growth and enhancement of the program faculty, and a pool of highly competitive applicants (including women and under-represented minorities). The program has very engaged and highly expert internal and external advisory committees, who provide real-time advice about the program's priorities, systems and directions. Members of the program faculty have a breadth of interests and expertise, and are proven mentors in the rheumatic diseases, immunology, molecular biology and genetics, cell biology, epidemiology and biostatistics. The overall goal of this program remains the development of 2 postdoctoral fellows each year (4 trainee slots total) into outstanding academic investigators in rheumatic disease, through rigorous instruction in research methodology and immersion in outstanding quality mentored research projects. Our training environment is focused on providing a productive clinical and translational research training program. The following specific aims will be pursued: [1] Provide rigorous training in investigational methods to rheumatology postdoctoral fellows, applicable to the conduct of both clinical and basic research; [2] Utilize clinical centers of excellence to provide access to well-defined rheumatic disease patient populations, enabling fellow projects to be efficiently conducted on established patient cohorts; [3] Engage postdoctoral fellows in high caliber research projects addressing important questions under the supervision of nationally renowned faculty; [4] Integrate multi-layered mentorship for each postdoctoral fellow to accomplish productive research, independence, and development of a successful academic career; and [5] Assess, and modify as needed (through incorporating feedback from trainees, training program faculty, and internal and external advisory committees), the outcomes of this training environment through assessing benchmarks of academic and programmatic achievement, including peer-reviewed publications, external research funding, post-training academic position, and recruitment of underrepresented minorities.