Bioinformatics Core

生物信息学核心

• 批准号: 8716085
• 负责人: FAYE SCHILKEY
• 金额: $ 77.75万
• 依托单位: NEW MEXICO STATE UNIVERSITY LAS CRUCES
• 依托单位国家: 美国
• 资助国家: 美国
• 起止时间: 至
• 项目状态: 未结题
• 来源: https://reporter.nih.gov/project-details/8716085
• 关键词: Academia; Achievement; Adopted; Area; Bioinformatics; Biological Phenomena; Biomedical Research; Biotechnology; Cancer Biology; Chromatin Structure; Collaborations; Color; Commit; Communication; Complex; Consult; DNA Methylation; DNA Resequencing; DNA Sequence; Data; Databases; Dedications; Development; Diagnostic Procedure; Disease; Drug Industry; Educational workshop; Emerging Technologies; Faculty; Fluorescence; Foundations; Gene Expression Profile; Generations; Genes; Genome; Genomics; Genotype; Germ Lines; Goals; Health Professional; Homo sapiens; Housing; Individual; Internships; Knowledge; Knowledge Discovery; Medicine; Mentorship; MicroRNAs; Mining; Mission; Molecular; New Mexico; North America; Productivity; Provider; RNA Splicing; Regulation; Research; Research Infrastructure; Research Institute; Research Personnel; Research Support; Resources; Role; Scientist; Series; Services; Software Tools; Students; Surveys; Techniques; Technology; Training; Training and Education; Universities; Variant; base; biological research; biomedical scientist; cohort; college; data mining; education planning; experience; field study; functional genomics; genome sequencing; innovation; mRNA Expression; next generation; next generation sequencing; operation; outreach; prognostic; research study; skills; software development; symposium; teacher; tool; trait; transcriptomics

. NGS technologies have transformed the way in which research is conducted. The sheer scale of inquiry has been expanded to the extent that whole genomes and transcriptomes of cohorts of individuals can be surveyed in a single experiment. Moreover, sequencing can be used to probe biological phenomena at multiple levels of regulation, including germ-line variation, DNA methylation, mRNA expression and splice form abundance, microRNA expression, and chromatin structure exploration. NGS is also displacing other technologies, in particular the use of fixed-content chips for genotyping. NGS is being applied in every field of biological research, and will be an essential tool in the development of individualized medicine. Sequence data without sophisticated bioinformatics is essentially useless. Having a technology partner consisting of an experienced team of bioinformatics researchers and analysts, co-located with the sequencing operation is unprecedented in New Mexico. The SBC will continue to provide the network turn-key access to discovery¿ enabling sequencing and bioinformatics.

． NGS技术已经改变了进行研究的方式。规模之大