Dartmouth Lead Participation in NCI National Clinical Trials Network

达特茅斯牵头参与 NCI 国家临床试验网络

• 批准号: 8605705
• 负责人: Konstantin H. Dragnev
• 金额: $ 37.59万
• 依托单位: DARTMOUTH COLLEGE
• 依托单位国家: 美国
• 财政年份: 2014
• 资助国家: 美国
• 起止时间: 2014-04-16 至 2019-02-28
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/8605705
• 关键词: Address; Adult; Advanced Malignant Neoplasm; Back; Basic Science; Cancer Biology; Cancer Patient; Cancer and Leukemia Group B; Caring; Catchment Area; Clinical; Clinical Oncology; Clinical Research; Clinical Treatment; Clinical Trials; Clinical Trials Cooperative Group; Clinical Trials Network; Collaborations; Comprehensive Cancer Center; Conduct Clinical Trials; Consent; Cooperative Group Program; Development; Diagnosis; Diagnostic; Disease; Education; Eligibility Determination; Engineering; Enrollment; Evaluation; Funding; Funding Opportunities; Future; Geographic Locations; Goals; Gynecologic Oncology Group; Health; Image; Immunology; Industry; Institution; Interdisciplinary Study; Knowledge; Laboratories; Lead; Leadership; Lebanon; Malignant Neoplasms; Medical center; Mission; Monitor; Multi-Institutional Clinical Trial; National Cancer Institute; New England; New Hampshire; Norris Cotton Cancer Center; Nursing Research; Oncology Group; Patient Care; Patients; Phase; Phase III Clinical Trials; Positioning Attribute; Preventive; Principal Investigator; Process; Protocols documentation; Radiation Therapy Oncology Group; Randomized; Recording of previous events; Reporting; Request for Applications; Research; Research Infrastructure; Research Personnel; Resource Sharing; Rural; Schools; Science; Scientist; Services; Site; System; Target Populations; Therapeutic; Therapy Clinical Trials; Translating; Translational Research; Vermont; anticancer research; base; cancer care; cancer imaging; cancer therapy; clinical application; college; community based practice; design; innovation; interest; medical schools; medical specialties; medically underserved population; member; multidisciplinary; patient population; prevent; programs; public health relevance; response; symposium; treatment trial; tumor

DESCRIPTION (provided by applicant): Norris Cotton Cancer Center (NCCC), the keystone of the cancer-related activities of both Dartmouth College, and its Geisel School of Medicine, and Dartmouth-Hitchcock Health, will participate in the NCI's National Clinical Trials Network as a Lead Academic Participating Site. NCCC has a long history of leadership in national cooperative group clinical trials, dating back to serving as an operating center for CALGB, and more recently as a full member of CALGB's successor (the Alliance), RTOG, and COG, and as an Affiliate member of GOG. As the only NCI-designated Comprehensive Cancer Center in northern New England, NCCC currently serves annually over 5,200 new and 30,000 returning cancer patients. NCCC is the specialty academic center for Vermont and New Hampshire, anchoring a network of 17 community- based practice sites across the region and receiving referrals of rare and advanced cancers, the target population for enrollment on innovative clinical. Trials, from a large geographic catchment area. Within Dartmouth, NCCC has a central Office of Clinical Research (OCR) which coordinates full participation in the entire range of available clinical trials. NCCC intends to participate in all 6 pending NCI-designated networks, expanding its prior focus on participation in the Alliance. We anticipate earning annually close to 400 enrollment credits for adult subjects on studies, including a projected 74 consented subjects on interventional therapeutic trial s. Care at DH is organized into 17 designated interdisciplinary disease-based teams which bring together all relevant specialties, 14 on a weekly basis, for new patient conferences at which eligibility for enrollment on clinical trials is assessed routinely. NCCC research nurses assigned to these Clinical Oncology Groups (COGs) are responsible for keeping the teams informed of available trials, and the NCCC clinical trials management system (Velos eResearch) provides the teams reports tracking current enrollment. While highest priority is given to translating NCCC science into clinical application, Dartmouth's size precludes most single-institution studies, and national cooperative group trials are prioritized ahead of industry initiated studies for fulfillment of NCCC's clinical research mission.

描述（由申请人提供）：Norris Cotton癌症中心（NCCC）是达特茅斯学院及其Geisel医学院和达特茅斯-希区柯克健康中心癌症相关活动的重点，将作为主要学术参与站点参与NCI的国家临床试验网络。NCCC在国家合作小组临床试验方面有着悠久的领导历史，可以追溯到CALGB的运营中心，最近成为CALGB的继任者（联盟），RTOG和COG的正式成员，以及GOG的附属成员。作为新英格兰北部唯一一家nci指定的综合癌症中心，NCCC目前每年为超过5,200名新癌症患者和30,000名复发癌症患者提供服务。NCCC是佛蒙特州和新罕布什尔州的专业学术中心，在该地区建立了一个由17个社区实践站点组成的网络，并接受罕见和晚期癌症的转诊，这是创新临床登记的目标人群。试验，从一个大的地理集水区。在达特茅斯，NCCC有一个中央临床研究办公室（OCR），负责协调所有可用临床试验的全面参与。NCCC计划参与所有6个未决的nci指定网络，扩大其先前对参与联盟的关注。我们预计每年的收入接近