Positive affect skills for depression: Optimizing internet and mobile delivery

抑郁症的积极影响技巧：优化互联网和移动交付

• 批准号: 8701768
• 负责人: JUDITH T MOSKOWITZ
• 金额: $ 23.55万
• 依托单位: NORTHWESTERN UNIVERSITY AT CHICAGO
• 依托单位国家: 美国
• 财政年份: 2014
• 资助国家: 美国
• 起止时间: 2014-08-08 至 2017-07-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/8701768
• 关键词: Adherence; Adult; Advertising; Affect; American; Behavioral inhibition; Biological; Cellular Phone; Centers for Disease Control and Prevention (U.S.); Chronic Disease; Clinical; Data; Electronic Mail; Emotions; Endogenous depression; Ensure; Evaluation; Exercise; Feedback; Goals; Incentives; Individual; Internet; Intervention; Lead; Learning; Life; Literature; Major Depressive Disorder; Mediator of activation protein; Mental Depression; Meta-Analysis; Methods; Outcome; Outcome Measure; Participant; Persons; Physical Function; Plague; Preparation; Psychological reinforcement; Public Health; Quality of life; Randomized; Randomized Controlled Trials; Recruitment Activity; Reporting; Research; Rewards; Risk; Sampling; Severities; Stress; System; Telephone; Testing; Time; United States National Institutes of Health; Work; base; clinical practice; comparative; computerized; coping; cost; cost effectiveness; daily functioning; depressive symptoms; emotional experience; experience; follow-up; handheld mobile device; improved; innovation; peer; positive emotional state; programs; psychologic; public health relevance; self help; skills; subthreshold depression; uptake; usability; virtual; web site

DESCRIPTION (provided by applicant): Depression is a major public health problem. Even slight elevations in depressive symptoms are associated with significant deficits in daily functioning. Only 50% of Americans with depression receive adequate treatment, and one-third of those receiving treatment do not benefit. There is now evidence that internet-based depression interventions can effectively reach large numbers of people at low cost, but they commonly have problems with high attrition and low adherence. We propose an intervention to reduce depressive symptoms by adapting our existing internet- based positive affect skills intervention for individuals with depression. We will develop and test innovative features for increasing adherence including exercises for use on mobile devices in real-life situations; very brief contact with a study facilitator; peer support via a private, moderated internet forum; and optional goals and challenges that provide users with reinforcement and feedback. The materials and delivery method will undergo multiple cycles of user testing and comparative evaluation, followed by a randomized test comparing several different versions of the intervention. We aim to 1) Maximize acceptability and relevance of intervention content for people with elevated depressive symptoms or clinical depression; (2) Develop methods for boosting retention and adherence, and (3) collect preliminary data regarding proximal mediators of efficacy of the program for reducing levels of depressive symptoms. The proposed study will extend the literature and inform clinical practice by gathering evidence regarding efficacy of positive psychological interventions; optimizing an online intervention for depression that has the potential for widespread reach and dissemination; and maximizing retention and adherence, two key components of successful psychological interventions.

描述（由申请人提供）：抑郁症是一个主要的公共卫生问题。即使是轻微的抑郁症状也与日常功能的严重缺陷有关。只有50%的美国抑郁症患者接受了适当的治疗，三分之一接受治疗的人没有受益。现在有证据表明，基于互联网的抑郁症干预措施可以有效地以低成本接触到大量人群，但它们通常存在高损耗和低依从性的问题。我们提出了一种干预措施，以减少抑郁症状，通过调整我们现有的基于互联网的积极影响技能干预抑郁症患者。我们将开发和测试创新功能，以提高依从性，包括在现实生活中使用移动的设备上的练习;与研究主持人的简短联系;通过私人，主持的互联网论坛的同行支持;以及为用户提供强化和反馈的可选目标和挑战。材料和输送方法将经历多个周期的用户测试和比较评价，然后进行随机测试，比较几种不同版本的干预措施。我们的目标是1）最大限度地提高抑郁症状或临床抑郁症患者干预内容的可接受性和相关性;（2）开发提高保留和依从性的方法，以及（3）收集有关该计划降低抑郁症状水平的疗效的近端介质的初步数据。这项拟议的研究将通过收集有关积极心理干预有效性的证据来扩展文献并为临床实践提供信息;优化具有广泛影响和传播潜力的抑郁症在线干预;最大限度地提高保留和坚持，这是成功心理干预的两个关键组成部分。