Enhancing Kidney Donation Through Live Organ Video Educated Donors (LOVED)

通过受过教育的活体器官视频捐赠者加强肾脏捐赠(喜爱)

基本信息

项目摘要

DESCRIPTION (provided by applicant): Chronic Kidney Disease is diagnosed in four times as many African Americans (AAs) as Whites and nearly twice as many AAs perish from the condition. Kidney transplantation offers the best outcomes for patients with End Stage Renal Disease (ESRD) but rates of procurement far outnumber cadaver organ availability, especially among AAs. A superior option is living donor kidney transplantation (LDKT). Since AAs comprise only 18.5% of LDKT recipients, innovative and culturally preferred strategies are needed to increase LDKT within the AA community. We hypothesize that a patient-centered, two tiered culturally sensitive education/motivation intervention targeting AA ESRD patients and potential donors (PDs) using mobile health (mHealth) technology will result in: 1) increased ESRD patients' willingness to ask for donation; 2) increased number of PDs who complete medical evaluation; and, 3) increased number of LDKTs. We will leverage mHealth technology as the delivery mechanism to maximize large scale dissemination potential. Guided by behavioral change and technology acceptability theories, the Live Organ Video Educated Donor [LOVED] program will be developed to address two domains. LOVED I will be tailored for AA ESRD patients and navigated by an AA LDKT recipient. LOVED II will be tailored for potential LDKT donors and navigated by an AA LDKT donor. iPad program delivery will include testimonial audio/video clips, home-work assignments, videoconferencing, chat room sessions, and text/emails. The proposed mixed methods research utilizes qualitative and quantitative studies in a 3 phase process of development that will involve: 1) Development of LOVED I and II technical content and delivery formats guided by behavioral and technological theories using 9 focus groups (8 per group) of AA LDKT recipients/donors, ESRD LDKT eligible patients, PDs who failed to complete screening and transplant healthcare provider team. 2) Conduct 3 month LOVED I and II proof of concept studies (LOVED I = 24 LDKT eligible patients; LOVED II = 24 PDs who did not complete screening) to assess program acceptability, feasibility, changes in self efficacy and attitudes. Also assessed will be % ESRD patients who identify PDs, % PDs who complete screening, % LDKTs and participants' perceptions of cultural competence of intervention including levels of trust, discrimination, shared decision making and literacy. 3) Conduct two 6 month 2-arm randomized control trials (LOVED I vs. standard of care, N=60; LOVED II vs. standard of care, N=80) to generate estimates needed for design of a large scale RCT.
描述(由申请人提供):慢性肾脏疾病的确诊人数是白人的四倍,死于这种疾病的非洲裔美国人几乎是白人的两倍。肾移植为终末期肾病(ESRD)患者提供了最好的结果,但采购率远远超过身体器官的可获得性,尤其是在AA中。更好的选择是活体供肾移植(LDKT)。由于再生障碍性贫血仅占LDKT接受者的18.5%,因此需要创新和文化偏好的策略来增加再生障碍性贫血社区内的LDKT。我们假设,针对AA ESRD患者和使用移动健康(MHealth)技术的潜在捐赠者(PD)的以患者为中心的两级文化敏感教育/动机干预将导致:1)ESRD患者要求捐献的意愿增加;2)完成医学评估的PD数量增加;以及3)LDKT数量增加。我们将利用移动健康技术作为交付机制,最大限度地发挥大规模传播潜力。在行为改变和技术可接受性理论的指导下,活体器官视频教育捐赠者[LOVE]计划将发展为解决两个领域。Love I将为AA ESRD患者量身定做,并由AA LDKT接受者导航。LOVE II将为潜在的LDKT捐赠者量身定做,并由AA LDKT捐赠者导航。IPad的程序交付将包括推荐性音频/视频剪辑、家庭工作任务、视频会议、聊天室会话和文本/电子邮件。拟议的混合方法研究在3个阶段的开发过程中利用定性和定量研究,包括:1)在行为和技术理论指导下,使用9个重点小组(每组8个)开发LOVE I和II技术内容和交付格式,这些焦点群体包括AA LDKT接受者/捐赠者、符合ESRD LDKT资格的患者、未能完成筛查和移植医疗保健提供者团队的PD。2)进行为期3个月的LOVE I和II概念验证研究(LOVE I=24名符合LDKT条件的患者;LOVE II=24名未完成筛查的PD),以评估计划的可接受性、可行性、自我效能和态度的变化。还将评估识别PD的ESRD患者的百分比、完成筛查的PD的百分比、LDKT的百分比以及参与者对干预的文化能力的看法,包括信任、歧视、共同决策和识字水平。3)进行两个6个月的双臂随机对照试验(LOVE I vs.照护标准,N=60;LOVE II VS照护标准,N=80),以产生设计大规模随机对照试验所需的估计。

项目成果

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PRABHAKAR K BALIGA其他文献

PRABHAKAR K BALIGA的其他文献

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{{ truncateString('PRABHAKAR K BALIGA', 18)}}的其他基金

Enhancing Kidney Donation Through Live Organ Video Educated Donors (LOVED)
通过受过教育的活体器官视频捐赠者加强肾脏捐赠(喜爱)
  • 批准号:
    8549239
  • 财政年份:
    2012
  • 资助金额:
    $ 25.81万
  • 项目类别:
Enhancing Kidney Donation Through Live Organ Video Educated Donors (LOVED)
通过受过教育的活体器官视频捐赠者加强肾脏捐赠(喜爱)
  • 批准号:
    9132776
  • 财政年份:
    2012
  • 资助金额:
    $ 25.81万
  • 项目类别:
Enhancing Kidney Donation Through Live Organ Video Educated Donors (LOVED)
通过受过教育的活体器官视频捐赠者加强肾脏捐赠(喜爱)
  • 批准号:
    8504018
  • 财政年份:
    2012
  • 资助金额:
    $ 25.81万
  • 项目类别:
A Program to Increase Living Donations in African Americans
增加非裔美国人活体捐赠的计划
  • 批准号:
    8054013
  • 财政年份:
    2010
  • 资助金额:
    $ 25.81万
  • 项目类别:
A Program to Increase Living Donations in African Ameri*
增加非裔美国人活体捐赠的计划*
  • 批准号:
    6912558
  • 财政年份:
    2002
  • 资助金额:
    $ 25.81万
  • 项目类别:
A Program to Increase Living Donations in African Americans
增加非裔美国人活体捐赠的计划
  • 批准号:
    7668673
  • 财政年份:
    2002
  • 资助金额:
    $ 25.81万
  • 项目类别:
A Program to Increase Living Donations in African Americans
增加非裔美国人活体捐赠的计划
  • 批准号:
    7477140
  • 财政年份:
    2002
  • 资助金额:
    $ 25.81万
  • 项目类别:
A Program to Increase Living Donations in African Ameri*
增加非裔美国人活体捐赠的计划*
  • 批准号:
    6848604
  • 财政年份:
    2002
  • 资助金额:
    $ 25.81万
  • 项目类别:
A Program to Increase Living Donations in African Americans
增加非裔美国人活体捐赠的计划
  • 批准号:
    8124926
  • 财政年份:
    2002
  • 资助金额:
    $ 25.81万
  • 项目类别:
A Program to Increase Living Donations in African Ameri*
增加非裔美国人活体捐赠的计划*
  • 批准号:
    7078590
  • 财政年份:
    2002
  • 资助金额:
    $ 25.81万
  • 项目类别:

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检查非洲裔美国成人艾滋病毒感染者抗逆转录病毒药物依从轨迹的社会决定因素
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针对非裔美国 MSM 的戒烟/药物依从性干预
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A smoking cessation/medication adherence intervention for African American MSM
针对非裔美国 MSM 的戒烟/药物依从性干预
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