Training Program in the Genetic Basis of Pediatric Gastrointestinal Disorders

儿科胃肠道疾病遗传基础培训计划

• 批准号: 8666845
• 负责人: Nancy Bettina Spinner
• 金额: $ 13.75万
• 依托单位: CHILDREN'S HOSP OF PHILADELPHIA
• 依托单位国家: 美国
• 财政年份: 2014
• 资助国家: 美国
• 起止时间: 2014-07-01 至 2019-06-30
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/8666845
• 关键词: Childhood; Gastrointestinal Diseases; Genetic; Training Programs; base

DESCRIPTION (provided by applicant): Training in the genetic basis of pediatric gastrointestinal disorders: The revolutions in genetics and genomics have led to discoveries in a range of GI diseases, many of which affect the health of children. Pediatric gastroenterologists who are trained in genetic research will be essential in the effort to identify novel genetic cause of GI disease, reveal their molecular mechanisms, and translate them into therapy. The outstanding laboratory, translational, and clinical research at CHOP and the Perelman School of Medicine (PSOM) present an ideal environment for research career development in the genetics of pediatric GI disease. The overarching goals of the this training program are to: Train a cadre of committed researchers to investigate the genetic basis of pediatric GI disease and to use this knowledge to improve the health of children and adults. Provide these individuals with the skill sets and foundation for career advancement. Encourage innovation and leadership in academic pediatric GI. The Specific Aims of this training program are to: Identify, recruit and foster the career development of post-doctoral research trainees from the pool of CHOP GI fellows, PSOM GI fellows, and other scientists committed to training and career development in the genetics of pediatric gastrointestinal disease. Match trainee strengths and interests with mentoring teams. Provide intensive mentored research experience and training with dedicated faculty. Provide career mentoring, including training on successful grant and manuscript preparation. Bring together faculty and fellows through seminar series and other academic activities to create a collaborative community of physician-scientists. Provide guidance for structured learning opportunities on the principles of genetic research, including research ethics and the protection of animal and human subjects. To achieve these goals, we have designed a training program comprising: Two years of support per trainee, with a total of 4 training slots each year (2 slots in the first year). Mentored independent research with a team approach and scholarship oversight. Career mentoring including individualized independent development plans (IDP), seminars and workshops focusing on professional development and career advancement skills. Didactic opportunities designed to provide specific research skills. Seminars, workshops and journal clubs focusing on research and progress in the field.

描述（由申请人提供）：儿童胃肠道疾病遗传基础培训：遗传学和基因组学的革命导致了一系列胃肠道疾病的发现，其中许多影响儿童健康。在遗传学研究方面受过训练的儿科胃肠病学家在识别胃肠道疾病的新遗传原因，揭示其分子机制并将其转化为治疗方面至关重要。CHOP和佩雷尔曼医学院（PSOM）出色的实验室、转化和临床研究为儿科胃肠道疾病遗传学的研究事业发展提供了理想的环境。该培训项目的总体目标是：培养一批致力于研究儿童胃肠道疾病遗传基础的研究人员，并利用这些知识改善儿童和成人的健康。为这些人提供职业发展所需的技能和基础。鼓励儿科GI学术领域的创新和领导。该培训计划的具体目标是：从CHOP GI研究员、PSOM GI研究员和其他致力于儿科胃肠道疾病遗传学培训和职业发展的科学家中确定、招募和促进博士后研究培训生的职业发展。将培训生的优势和兴趣与指导团队相匹配。提供密集的指导研究经验和培训与专门的教师。提供职业指导，包括成功拨款和稿件准备方面的培训。通过系列研讨会和其他学术活动将教师和研究员聚集在一起，创建一个医生-科学家的合作社区。为结构化的遗传研究原则学习机会提供指导，包括研究伦理