Training Program in the Genetic Basis of Pediatric Gastrointestinal Disorders

儿科胃肠道疾病遗传基础培训计划

• 批准号: 8666845
• 负责人: Nancy Bettina Spinner
• 金额: $ 13.75万
• 依托单位: CHILDREN'S HOSP OF PHILADELPHIA
• 依托单位国家: 美国
• 财政年份: 2014
• 资助国家: 美国
• 起止时间: 2014-07-01 至 2019-06-30
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/8666845
• 关键词: Childhood; Gastrointestinal Diseases; Genetic; Training Programs; base

DESCRIPTION (provided by applicant): Training in the genetic basis of pediatric gastrointestinal disorders: The revolutions in genetics and genomics have led to discoveries in a range of GI diseases, many of which affect the health of children. Pediatric gastroenterologists who are trained in genetic research will be essential in the effort to identify novel genetic cause of GI disease, reveal their molecular mechanisms, and translate them into therapy. The outstanding laboratory, translational, and clinical research at CHOP and the Perelman School of Medicine (PSOM) present an ideal environment for research career development in the genetics of pediatric GI disease. The overarching goals of the this training program are to: Train a cadre of committed researchers to investigate the genetic basis of pediatric GI disease and to use this knowledge to improve the health of children and adults. Provide these individuals with the skill sets and foundation for career advancement. Encourage innovation and leadership in academic pediatric GI. The Specific Aims of this training program are to: Identify, recruit and foster the career development of post-doctoral research trainees from the pool of CHOP GI fellows, PSOM GI fellows, and other scientists committed to training and career development in the genetics of pediatric gastrointestinal disease. Match trainee strengths and interests with mentoring teams. Provide intensive mentored research experience and training with dedicated faculty. Provide career mentoring, including training on successful grant and manuscript preparation. Bring together faculty and fellows through seminar series and other academic activities to create a collaborative community of physician-scientists. Provide guidance for structured learning opportunities on the principles of genetic research, including research ethics and the protection of animal and human subjects. To achieve these goals, we have designed a training program comprising: Two years of support per trainee, with a total of 4 training slots each year (2 slots in the first year). Mentored independent research with a team approach and scholarship oversight. Career mentoring including individualized independent development plans (IDP), seminars and workshops focusing on professional development and career advancement skills. Didactic opportunities designed to provide specific research skills. Seminars, workshops and journal clubs focusing on research and progress in the field.

描述(申请人提供)：儿童胃肠道疾病的遗传学基础培训：遗传学和基因组学的革命导致了一系列胃肠道疾病的发现，其中许多疾病影响儿童的健康。接受过基因研究培训的儿科胃肠病专家在努力确定胃肠道疾病的新遗传原因、揭示其分子机制并将其转化为治疗方法方面将是必不可少的。CHOP和佩雷尔曼医学院(PSOM)出色的实验室、转化和临床研究为儿科GI疾病遗传学的研究生涯发展提供了理想的环境。这一培训计划的总体目标是：培训一支忠诚的研究人员队伍，调查儿科GI疾病的遗传基础，并利用这一知识改善儿童和成人的健康。为这些人提供职业发展所需的技能和基础。鼓励儿科学术领域的创新和领导力。该培训计划的具体目标是：从CHOP GI研究员、PSOM GI研究员和其他致力于儿科胃肠道疾病遗传学培训和职业发展的科学家中识别、招募和促进博士后研究实习生的职业发展。将学员的优势和兴趣与指导团队相匹配。与敬业的教师一起提供密集的指导研究经验和培训。提供职业指导，包括关于成功拨款和手稿准备的培训。通过系列研讨会和其他学术活动将教职员工和研究员聚集在一起，创建一个由医生和科学家组成的协作社区。就遗传研究的原则，包括研究伦理，为有组织的学习机会提供指导 以及对动物和人类主体的保护。为了实现这些目标，我们设计了一个培训方案，包括：每个学员两年的支持，每年总共有4个培训时段(第一年2个时段)。以团队方式和学术监督指导独立研究。职业指导，包括个性化的独立发展计划、侧重于职业发展和职业发展技能的研讨会和讲习班。旨在提供特定研究技能的授课机会。研讨会、讲习班和期刊俱乐部，重点关注该领域的研究和进展。