Virology Core

病毒学核心

• 批准号: 8708739
• 负责人: JULIE AE NELSON
• 金额: --
• 依托单位: UNIV OF NORTH CAROLINA CHAPEL HILL
• 依托单位国家: 美国
• 财政年份: 2014
• 资助国家: 美国
• 起止时间: 2014-08-01 至 2016-07-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/8708739
• 关键词: AIDS clinical trial group; AIDS/HIV problem; Acquired Immunodeficiency Syndrome; Acute; Advisory Committees; Applications Grants; Area; Bedside Testings; Biological Assay; Blood; Clinical Trials; Clinical Trials Design; Collaborations; Communities; Consultations; Detection; Development; Diagnosis; Diagnostic; Drug Formulations; Enrollment; Epidemic; Evaluation; Experimental Designs; Feedback; Future; Goals; Grant; HIV; HIV Genome; HIV Infections; HIV diagnosis; Hepatitis B Virus; Hepatitis C virus; Human Papillomavirus; Human Resources; IMPAACT; Industry; International; Laboratories; Leadership; Link; Malignant Neoplasms; Mentors; Mentorship; Monitor; Patients; Recording of previous events; Research; Research Activity; Research Infrastructure; Research Personnel; Russia; Sampling; Scientist; Serum; Services; Site; Specimen Handling; Strategic Planning; Surveys; Technology Transfer; Testing; Training; United States National Institutes of Health; Viral; Virus; Virus Diseases; Work; assay development; base; experience; follow-up; genital secretion; improved; member; point of care; programs; protocol development; quality assurance; tool; transmission process; virology; working group

The goals of the Virology Core are to enhance the research capacity of the UNC CFAR research community by providing access to state-of-the-art tools for diagnosis and monitoring HIV+ patients in clinical trials, and providing leadership to promote HIV/AIDS research in this area through collaboration, training, and mentoring. The specific aims are to 1) provide quality viral assays and services, 2) provide training and mentorship to the domestic and international CFAR community and build capacity at international sites, 3) provide leadership through activities locally, nationally, and internationally, 4) support NIH networks and CFAR-CFAR collaborations by participating in CHAVI, HPTN, IMPAACT, and ACTG, 5) support new CFAR initiatives through collaborations with UNC CFAR members, and 6) engage in evaluation and strategic planning, using input from user surveys, an Internal Advisory Board, and the CFAR External Advisory Board. Through these activities, the Virology Core will continue to provide key infrastructure support for the HIV/AIDS research activity of the CFAR membership. These activities will have a significant impact on the future of the epidemic by providing HIV, HCV, and HPV viral assays, including ultra-low copy number and POC assays, training and mentoring new US and international scientists, and providing leadership locally, nationally, and globally.

病毒学核心的目标是提高研究机构的研究能力 提供最先进的工具，用于诊断和监测临床试验中的艾滋病毒阳性患者，以及 通过合作、培训和指导，领导促进这一领域的艾滋病毒/艾滋病研究。 具体目标是：1）提供高质量的病毒检测和服务，2）为 国内和国际CFAR社区，并在国际站点建立能力，3）提供领导 通过地方、国家和国际活动，4）支持NIH网络和CFAR-CFAR 通过参与CHAVI、HPTN、IMPAACT和ACTG进行合作，5）支持新的CFAR倡议 通过与CCFAR成员的合作，以及6）参与评估和战略规划， 来自用户调查、内部咨询委员会和CFAR外部咨询委员会的意见。通过这些 活动，病毒学核心将继续为艾滋病毒/艾滋病研究提供关键的基础设施支持 CFAR成员的活动。这些活动将对疫情的未来产生重大影响 通过提供HIV、HCV和HPV病毒检测，包括超低拷贝数和POC检测、培训和 指导新的美国和国际科学家，并在当地，国家和全球范围内提供领导。