UNC Center for AIDS Research Core J VIM

项目概要/摘要-病毒学、免疫学和微生物学（Vim）核心 病毒学，免疫学和微生物学（Vim）核心的广泛，长期目标是提供 为艾滋病毒/艾滋病相关的基础和临床艾滋病毒研究提供实验室支持。的 具体目标包括：（1）提供各种具有成本效益的服务，（2）开发和评估 适用于CFAR调查人员研究的新技术，（3）支持CFAR倡议， 合作研究，（4）促进CCFAR核心，CCFAR SWG和其他 CFAR，（5）在病毒学、免疫学和免疫学领域提供指导、培训、教育和推广， 微生物学;（6）参与评估和战略规划。为了实现这些目标，Vim Core 与CSCCFAR调查人员合作，提供所需的服务、标本、设备或培训 研究人员为了实现他们的研究目标。核心有助于赠款写作，设计 实验，并记录结果。所提供的服务包括临床试验的标本处理， 提供来自HIV阳性和HIV阴性个体的样本，病毒定量，流式细胞术， 抗体和细胞因子的测量以及艾滋病毒和其他性传播感染的诊断。 新的检测方法是根据研究者的要求和CFAR的优先研究领域开发的。 核心小组的管理和战略规划将通过与核心小组主任协商、调查 CFAR成员，内部咨询委员会，外部咨询委员会，并通过讨论， CFAR撤退。

PROJECT SUMMARY/ABSTRACT –VIROLOGY, IMMUNOLOGY & MICROBIOLOGY (VIM) CORE The broad, long-term objectives of the Virology, Immunology & Microbiology (VIM) Core are to provide laboratory support for HIV/AIDS-related basic and clinical HIV research to the UNC CFAR community. The specific aims include: (1) provide access to a diverse array of cost-effective services, (2) develop and evaluate new technologies applicable to research by CFAR investigators, (3) support of CFAR initiatives and collaborative research, (4) promote synergy between UNC CFAR Cores, UNC CFAR SWGs, and other CFARs, (5) provide mentoring, training, education, and outreach in the areas of virology, immunology, and microbiology, and (6) engage in evaluation and strategic planning. To achieve these aims, the VIM Core collaborates with UNC CFAR investigators to provide the services, specimens, equipment, or training needed by the investigators to achieve their research goals. The Core contributes to grant writing, design of experiments, and write-up of results. The services offered include specimen processing for clinical trials, provision of specimens from HIV-positive and HIV-negative individuals, viral quantitation, flow cytometry, measurement of antibodies and cytokines, and diagnostics for HIV and other sexually transmitted infections. New assays are developed in response to investigator requests and priority research areas for the CFAR. Management and strategic planning of the Core will be guided by consultation with the Core Directors, surveys of the CFAR membership, an Internal Advisory Board, an External Advisory Board, and through discussions at CFAR retreats.