Virology, Immunology, and Microbiology Core

病毒学，免疫学和微生物学（Vim）核心的目标是通过提供最先进的工具研究，以及诊断和监测临床试验中的HIV-1阳性患者，来提高CIMCFAR研究社区的研究能力。Vim核心还为促进艾滋病毒/艾滋病研究提供领导 通过合作、培训和指导。具体目标是：1）提供高质量的病毒学、免疫学和微生物检测和服务; 2）为国内和国际CFAR社区提供培训和指导，并在国际研究中心建立能力; 3）通过在当地、国内和国际开展活动提供领导; 4）通过参与WIHS、HPTN、IMPAACT和ACTG，支持NIH网络和CFAR-CFAR合作，5）通过与CFAR成员的合作，支持CFAR的新举措，6）利用用户调查、内部咨询委员会和CFAR外部咨询委员会的投入，参与评估和战略规划。通过这些活动，病毒学、免疫学和微生物学核心将为CFAR成员的艾滋病毒/艾滋病和艾滋病毒合并感染研究活动提供关键的基础设施支持。这些活动将通过提供HIV-1和其他性传播感染检测（包括超低拷贝数和POC HIV-1检测），对艾滋病的未来产生重大影响 和核酸扩增检测非艾滋病毒性病），生物标本的采购和分发，免疫表型，功能和免疫遗传学测试，培训和指导新的美国和国际科学家，并提供领导当地，国家和全球。

The goals of the Virology, Immunology & Microbiology (VIM) Core are to enhance the research capacity of the UNC CFAR research community by providing access to state­ of-the-art tools research, and for diagnosis and monitoring HIV-1-positive patients in clinical trials. The VIM Core also provides leadership to promote HIVIAIDS research through collaboration, training, and mentoring. The specific aims are to 1) provide quality virologic, immunologic and microbiologic assays and services, 2) provide training and mentorship to the domestic and international CFAR community and build capacity at international sites, 3) provide leadership through activities locally, nationally, and internationally, 4) support NIH networks and CFAR-CFAR collaborations by participating in WIHS, HPTN, IMPAACT, and ACTG, 5) support new CFAR initiatives through collaborations with UNC CFAR members, and 6) engage in evaluation and strategic planning, using input from user surveys, an Internal Advisory Board, and the CFAR External Advisory Board. Through these activities, the Virology, Immunology & Microbiology Core will provide key infrastructure support for the HIVIAIDS and HIV­ coinfection research activity of the CFAR membership. These activities will have a significant impact on the future of the epidemic by providing assays for HIV-1 and other sexually transmitted infections (including ultra-low copy number and POC HIV-1 assays and nucleic acid amplification testing for non-HIV STis), biospecimen procurement and distribution, immune phenotype, function and immunogenetic testing, training and mentoring new US and international scientists, and providing leadership locally, nationally, and globally.