Administrative Core
Administrative Core
批准号:
8643873
负责人:
JEFFREY S GLENN
金额:
$20.39万
依托单位:
依托单位国家:
美国
项目类别:
财政年份:
2014
资助国家:
美国
项目状态:
已结题
起止时间:
2014-04-10 至 2019-03-31
中文摘要
行政核心的总体目标和目标是管理、协调和监督所有中心活动,以有效和最佳地支持该计划的目标,即开发能够治疗多种NIAID新出现和再出现的优先病原体病毒的新型宿主靶向抗病毒治疗药物,无论是单独使用还是与其他可用药物联合使用。行政核心将由杰弗里·格伦博士担任主任领导,他将主持由博士组成的科学咨询委员会。Terrence Blaschke、Gail Cassell、John mcchchison、Charles Rice、Douglas Richman和Raymond Schinazi为外部顾问,Gary Peltz、Daria Mochly-Rosen、Mark Kay、Vijay Pande、Chaitan Khosia、Purvesh Khatri和Harry Greenberg博士为内部成员。行政核心将寻求通过以下具体目标向整个计划及其组成项目和核心提供上述支持,这些目标是:
英文摘要
The overall objective and goals of the Administrative Core is to manage, coordinate, and supervise all Center activities to effectively and optimally support the Program's goals to develop new classes of host-targeting antiviral therapeutics that are capable of treating multiple NIAID Emerging and Re-emerging Priority Pathogen viruses, when used alone or in combination with other available agents. The Administrative Core will be led by Dr. Jeffrey Glenn as Director, who will anchor the Scientific Advisory Committee composed of Drs. Terrence Blaschke, Gail Cassell, John McHutchison, Charles Rice, Douglas Richman, and Raymond Schinazi as external advisors, and Gary Peltz, Daria Mochly-Rosen, Mark Kay, Vijay Pande, Chaitan Khosia, Purvesh Khatri, and Dr. Harry Greenberg as internal members. The Administrative Core will seek to deliver the above support to both the overall Program and its constituent Projects and Cores via the following specific aims, which are to:
1) Implement administrative & leadership mechanisms via a management plan that will facilitate
communication and cooperation among the Project leaders and with the greater consortium and investigators at other institutions so as to ensure a maximally productive research effort;
2) Monitor the progress of each of the research and pilot projects and their interactions with the scientific cores, and promotion of effective communication;
3) Provide an efficient, centralized unit for the appropriate fiscal and administrative operation of the Stanford CETR activities;
4) Provide infrastructure support for the Center investigators to develop collaborative studies with other members of the National CETR Program consortium and research groups.
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会议论文
Oral small molecule inhibitors of NSP4-mediated membrane-associated RNA replication of SARS-CoV-2 and other RNA viruses
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批准号:10514275
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项目类别:
-
资助金额:$926.66万
-
财政年份:2022
-
负责人:JEFFREY S GLENN
-
依托单位:
Development of outpatient antiviral cocktails against SARS-CoV-2 and other potential pandemic RNA viruses.
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批准号:10514264
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项目类别:
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资助金额:$6905.87万
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财政年份:2022
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负责人:JEFFREY S GLENN
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依托单位:
Administrative Core
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批准号:10514265
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项目类别:
-
资助金额:$599.61万
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财政年份:2022
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负责人:JEFFREY S GLENN
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依托单位:
Programmable antivirals: Targeting viral RNA secondary structures with LNAs and small molecules
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批准号:10514269
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项目类别:
-
资助金额:$891.52万
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财政年份:2022
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负责人:JEFFREY S GLENN
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依托单位:
Optimizing a small molecule inhibitor of SARS-CoV-2 replication and associated cytokine storm
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批准号:10681264
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项目类别:
-
资助金额:$75.84万
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财政年份:2021
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负责人:JEFFREY S GLENN
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依托单位:
Optimizing a small molecule inhibitor of SARS-CoV-2 replication and associated cytokine storm
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批准号:10470714
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项目类别:
-
资助金额:$77.21万
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财政年份:2021
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负责人:JEFFREY S GLENN
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依托单位:
Optimizing a small molecule inhibitor of SARS-CoV-2 replication and associated cytokine storm
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批准号:10187861
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项目类别:
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资助金额:$79.9万
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财政年份:2021
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负责人:JEFFREY S GLENN
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依托单位:
Advancing a broad-spectrum anti-influenza A virus RNA packaging inhibitor to an IND
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批准号:10165884
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项目类别:
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资助金额:$74.55万
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财政年份:2020
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负责人:JEFFREY S GLENN
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依托单位:
Rapid development of SARS-CoV-2 specific therapeutics that leverage virus specific RNA elements
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批准号:10115505
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项目类别:
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资助金额:$34.82万
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财政年份:2020
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负责人:JEFFREY S GLENN
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依托单位:
Advancing a broad-spectrum anti-influenza A virus RNA packaging inhibitor to an IND
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批准号:9750617
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项目类别:
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资助金额:$112.19万
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财政年份:2017
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负责人:JEFFREY S GLENN
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依托单位:
Advancing a broad-spectrum anti-influenza A virus RNA packaging inhibitor to an IND
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批准号:9973144
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项目类别:
-
资助金额:$111.3万
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财政年份:2017
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负责人:JEFFREY S GLENN
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依托单位:
Advancing Broad Spectrum Host-Targeting Antiviral Strategies to the Clinic
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批准号:8641475
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项目类别:
-
资助金额:$530.5万
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财政年份:2014
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负责人:JEFFREY S GLENN
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依托单位:
Advancing Broad Spectrum Host-Targeting Antiviral Strategies to the Clinic
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批准号:8836487
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项目类别:
-
资助金额:$547.11万
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财政年份:2014
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负责人:JEFFREY S GLENN
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依托单位:
Advancing Broad Spectrum Host-Targeting Antiviral Strategies to the Clinic
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批准号:9925707
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项目类别:
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资助金额:$32.91万
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财政年份:2014
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负责人:JEFFREY S GLENN
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依托单位:
Advancing Broad Spectrum Host-Targeting Antiviral Strategies to the Clinic
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批准号:9257257
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项目类别:
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资助金额:$603.28万
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财政年份:2014
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负责人:JEFFREY S GLENN
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依托单位:
PK-enhanced PI-Kinase (PI4K; PI5K) Inhibitors of RNA Viruses
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批准号:8643870
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项目类别:
-
资助金额:$142.55万
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财政年份:2014
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负责人:JEFFREY S GLENN
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依托单位:
Haploid genetic screen to identify host genes required for RNA virruses
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批准号:8643866
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项目类别:
-
资助金额:$41.23万
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财政年份:2014
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负责人:JEFFREY S GLENN
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依托单位:
Advancing a Novel Pangenotypic Inhibitor of Human Influenza Virus to an IND
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批准号:8895462
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项目类别:
-
资助金额:$133.3万
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财政年份:2014
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负责人:JEFFREY S GLENN
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依托单位:
The PIP2-virus interface and PI 4-kinase: novel biology and validation targets
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批准号:8449564
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项目类别:
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资助金额:$102.08万
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财政年份:2012
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负责人:JEFFREY S GLENN
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依托单位:
The PIP2-virus interface and PI 4-kinase: novel biology and validation targets
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批准号:8283753
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项目类别:
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资助金额:$112.78万
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财政年份:2012
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负责人:JEFFREY S GLENN
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依托单位:
海外基金