Administrative Core

行政核心

• 批准号: 10514265
• 负责人: JEFFREY S GLENN
• 金额: $ 599.61万
• 依托单位: STANFORD UNIVERSITY
• 依托单位国家: 美国
• 财政年份: 2022
• 资助国家: 美国
• 起止时间: 2022-05-16 至 2025-04-30
• 项目状态: 未结题
• 来源: https://reporter.nih.gov/project-details/10514265
• 关键词: 2019-nCoV; Antiviral Agents; Communication; Coronavirus; Development; Ensure; Goals; Infrastructure; Institution; Leadership; Mentors; Monitor; Outpatients; RNA Viruses; Research; Research Personnel; Research Project Grants; Supervision; drug development; operation; pandemic disease

ABSTRACT: The overall objective and goals of the Administrative Core is to manage, coordinate, and supervise all Center activities to effectively and optimally support the Stanford AViDD Center (“SyneRx”)’s goals to develop outpatient antiviral drugs for coronaviruses and other RNA viruses of pandemic potential, when used alone or in combination with other available agents. The Administrative Core will seek to deliver this support to both the overall Center and its constituent Projects and Cores by: 1) implementing administrative and leadership mechanisms via a management plan that will facilitate communication and cooperation among the Project and Core leaders and with the greater consortium and investigators at other institutions so as to ensure a maximally productive research effort; 2) monitoring the progress of each of the Research Projects and Scientific Cores relative to their milestones for drug development; 3) providing an efficient infrastructure support for new Developmental Research Projects and their oversight; 4) providing an efficient infrastructure support for new Mentored Projects and their oversight; 5) providing an efficient, centralized unit for the appropriate fiscal and administrative operation of SyneRx’s activities; and 6) providing dedicated regulatory support to help formulate and manage a successful regulatory strategy for AViDD Center projects.

摘要：行政核心的总体目标是管理、协调和 监督中心的所有活动，以有效和最佳地支持斯坦福大学AViDD中心（“SyneRx”）的 目标是开发针对冠状病毒和其他具有大流行潜力的RNA病毒的门诊抗病毒药物， 当单独使用或与其它可用试剂组合使用时。行政核心将努力实现这一目标。 支持整个中心及其组成项目和核心：1）实施行政管理 和领导机制，通过管理计划，将促进沟通与合作， 项目和核心领导人以及更大的财团和其他机构的调查人员，以便 确保最大限度地提高研究成果; 2）监督每个研究项目的进展情况 和科学核心相对于其药物开发的里程碑; 3）提供有效的基础设施 支持新的发展研究项目及其监督; 4）提供有效的基础设施 支持新的辅导项目及其监督; 5）为 SyneRx活动的适当财政和行政运作;以及6）提供专门的监管 提供支持，帮助制定和管理针对AViDD中心项目的成功监管策略。