Administrative Core
Administrative Core
批准号:
10514265
负责人:
JEFFREY S GLENN
金额:
$599.61万
依托单位:
依托单位国家:
美国
项目类别:
财政年份:
2022
资助国家:
美国
项目状态:
未结题
起止时间:
2022-05-16 至 2025-04-30
中文摘要
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英文摘要
ABSTRACT: The overall objective and goals of the Administrative Core is to manage, coordinate, and
supervise all Center activities to effectively and optimally support the Stanford AViDD Center (“SyneRx”)’s
goals to develop outpatient antiviral drugs for coronaviruses and other RNA viruses of pandemic potential,
when used alone or in combination with other available agents. The Administrative Core will seek to deliver this
support to both the overall Center and its constituent Projects and Cores by: 1) implementing administrative
and leadership mechanisms via a management plan that will facilitate communication and cooperation among
the Project and Core leaders and with the greater consortium and investigators at other institutions so as to
ensure a maximally productive research effort; 2) monitoring the progress of each of the Research Projects
and Scientific Cores relative to their milestones for drug development; 3) providing an efficient infrastructure
support for new Developmental Research Projects and their oversight; 4) providing an efficient infrastructure
support for new Mentored Projects and their oversight; 5) providing an efficient, centralized unit for the
appropriate fiscal and administrative operation of SyneRx’s activities; and 6) providing dedicated regulatory
support to help formulate and manage a successful regulatory strategy for AViDD Center projects.
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会议论文
Oral small molecule inhibitors of NSP4-mediated membrane-associated RNA replication of SARS-CoV-2 and other RNA viruses
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批准号:10514275
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项目类别:
-
资助金额:$926.66万
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财政年份:2022
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负责人:JEFFREY S GLENN
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依托单位:
Development of outpatient antiviral cocktails against SARS-CoV-2 and other potential pandemic RNA viruses.
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批准号:10514264
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项目类别:
-
资助金额:$6905.87万
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财政年份:2022
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负责人:JEFFREY S GLENN
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依托单位:
Programmable antivirals: Targeting viral RNA secondary structures with LNAs and small molecules
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批准号:10514269
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项目类别:
-
资助金额:$891.52万
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财政年份:2022
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负责人:JEFFREY S GLENN
-
依托单位:
Optimizing a small molecule inhibitor of SARS-CoV-2 replication and associated cytokine storm
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批准号:10681264
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项目类别:
-
资助金额:$75.84万
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财政年份:2021
-
负责人:JEFFREY S GLENN
-
依托单位:
Optimizing a small molecule inhibitor of SARS-CoV-2 replication and associated cytokine storm
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批准号:10470714
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项目类别:
-
资助金额:$77.21万
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财政年份:2021
-
负责人:JEFFREY S GLENN
-
依托单位:
Optimizing a small molecule inhibitor of SARS-CoV-2 replication and associated cytokine storm
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批准号:10187861
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项目类别:
-
资助金额:$79.9万
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财政年份:2021
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负责人:JEFFREY S GLENN
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依托单位:
Advancing a broad-spectrum anti-influenza A virus RNA packaging inhibitor to an IND
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批准号:10165884
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项目类别:
-
资助金额:$74.55万
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财政年份:2020
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负责人:JEFFREY S GLENN
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依托单位:
Rapid development of SARS-CoV-2 specific therapeutics that leverage virus specific RNA elements
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批准号:10115505
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项目类别:
-
资助金额:$34.82万
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财政年份:2020
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负责人:JEFFREY S GLENN
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依托单位:
Advancing a broad-spectrum anti-influenza A virus RNA packaging inhibitor to an IND
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批准号:9750617
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项目类别:
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资助金额:$112.19万
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财政年份:2017
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负责人:JEFFREY S GLENN
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依托单位:
Advancing a broad-spectrum anti-influenza A virus RNA packaging inhibitor to an IND
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批准号:9973144
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项目类别:
-
资助金额:$111.3万
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财政年份:2017
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负责人:JEFFREY S GLENN
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依托单位:
Administrative Core
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批准号:8643873
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项目类别:
-
资助金额:$20.39万
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财政年份:2014
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负责人:JEFFREY S GLENN
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依托单位:
Advancing Broad Spectrum Host-Targeting Antiviral Strategies to the Clinic
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批准号:8641475
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项目类别:
-
资助金额:$530.5万
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财政年份:2014
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负责人:JEFFREY S GLENN
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依托单位:
Advancing Broad Spectrum Host-Targeting Antiviral Strategies to the Clinic
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批准号:8836487
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项目类别:
-
资助金额:$547.11万
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财政年份:2014
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负责人:JEFFREY S GLENN
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依托单位:
Advancing Broad Spectrum Host-Targeting Antiviral Strategies to the Clinic
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批准号:9925707
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项目类别:
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资助金额:$32.91万
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财政年份:2014
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负责人:JEFFREY S GLENN
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依托单位:
Advancing Broad Spectrum Host-Targeting Antiviral Strategies to the Clinic
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批准号:9257257
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项目类别:
-
资助金额:$603.28万
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财政年份:2014
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负责人:JEFFREY S GLENN
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依托单位:
PK-enhanced PI-Kinase (PI4K; PI5K) Inhibitors of RNA Viruses
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批准号:8643870
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项目类别:
-
资助金额:$142.55万
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财政年份:2014
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负责人:JEFFREY S GLENN
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依托单位:
Haploid genetic screen to identify host genes required for RNA virruses
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批准号:8643866
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项目类别:
-
资助金额:$41.23万
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财政年份:2014
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负责人:JEFFREY S GLENN
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依托单位:
Advancing a Novel Pangenotypic Inhibitor of Human Influenza Virus to an IND
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批准号:8895462
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项目类别:
-
资助金额:$133.3万
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财政年份:2014
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负责人:JEFFREY S GLENN
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依托单位:
The PIP2-virus interface and PI 4-kinase: novel biology and validation targets
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批准号:8449564
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项目类别:
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资助金额:$102.08万
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财政年份:2012
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负责人:JEFFREY S GLENN
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依托单位:
The PIP2-virus interface and PI 4-kinase: novel biology and validation targets
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批准号:8283753
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项目类别:
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资助金额:$112.78万
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财政年份:2012
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负责人:JEFFREY S GLENN
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依托单位:
海外基金