Examining Innovative Obesity Treatment and Related Novel Constructs

检查创新的肥胖治疗方法和相关的新颖结构

• 批准号: 8729577
• 负责人: RACHEL D BARNES
• 金额: $ 15.59万
• 依托单位: YALE UNIVERSITY
• 依托单位国家: 美国
• 财政年份: 2011
• 资助国家: 美国
• 起止时间: 2011-09-20 至 2016-08-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/8729577
• 关键词: Address; Appointment; Area; Attention; Behavior; Behavioral; Binge Eating; Binge eating disorder; Body Weight decreased; Clinic; Clinical; Collaborations; Communities; Conduct Clinical Trials; Counseling; Data; Development; Diet; Doctor of Philosophy; Eating; Epidemic; Equipment and supply inventories; Ethics; Extramural Activities; Faculty; Food; Funding; Future; Goals; Health behavior; Health education; Individual; Internet; Intervention; Joints; Knowledge; Learning; Literature; Measurement; Measures; Mentored Patient-Oriented Research Career Development Award; Mentors; Mentorship; Metabolic syndrome; Methodology; Methods; North Carolina; Nutritional; Obesity; Online Systems; Outcome; Overweight; Paper; Patients; Population; Primary Health Care; Property; Provider; Psychiatry; Psychological Factors; Psychology; Psychometrics; Public Health; Public Health Schools; Publications; Publishing; Randomized Clinical Trials; Randomized Controlled Trials; Research; Research Activity; Research Design; Research Personnel; Research Project Grants; Research Training; Route; Sampling; Symptoms; System; Thinking; Time; Training; Universities; Weight; Work; base; career development; compliance behavior; design; eating pathology; experience; improved; innovation; interest; medical schools; medical specialties; member; motivational enhancement therapy; multidisciplinary; novel; nutrition; obesity treatment; post-doctoral training; professor; programs; psychologic; skills; treatment as usual; treatment response; weight loss intervention

DESCRIPTION (provided by applicant): This application is for a Mentored Patient-Oriented Research Career Development Award (K23). The candidate, Rachel D. Barnes, Ph.D., has a programmatic interest in innovative treatments for overweight and obesity within multidisciplinary teams and furthering understanding of novel weight-related variables. Dr. Barnes plans, as a junior faculty member at Yale University School of Medicine (YSM), to acquire the necessary skills to successfully obtain extramural funding and become an independent clinical researcher in the area of obesity. The training and research plan comprises the expert mentorship and collaboration of Carlos M. Grilo, Ph.D., Professor of Psychiatry at YSM, Professor of Psychology at Yale University, and Director of the Program for Obesity, Weight, and Eating Research, and Deborah Tate, Ph.D., Associate Professor with joint appointments in the Gillings School of Public Health in the Departments of Health Behavior and Health Education, and the Department of Nutrition at the University of North Carolina School of Medicine, Chapel Hill. These mentors, along with internationally recognized contributors from YSM, will assist Dr. Barnes in achieving and maximizing the training and research plans. Dr. Barnes plans to devote a minimum of 75% of her time to obtaining further knowledge and expertise in behavioral and psychological factors associated with obesity and in intervening with overweight and obesity. Her specific training development goals proposed for the K23 are to: 1) Acquire greater expertise with assessing and intervening with obesity in different settings; 2) Design and conduct a randomized clinical trial; and 3) Obtain training and perform research in psychological approaches relevant to improving clinical methods for intervening for obesity. The research plan for this application is comprised of three interrelated studies designed to: 1) Validate the Food Thought Suppression Inventory (FTSI) within an overweight and obese treatment seeking sample; 2) Examine the FTSI within a randomized controlled trial (RCT) for binge eating disorder; and 3) Conduct an innovative RCT treating obesity within primary care using an easily accessible and financially feasible internet treatment enhanced with motivational interviewing. Collectively, these studies will increase Dr. Barnes's knowledge of ethics and complexities of conducting clinical trials, including statistical sophistication and methodologies, and will inform the development of R01 applications. The proposed research has the potential to improve our understanding of a systems based, broad approach to treating obesity and novel weight-related constructs. The K23 will support Dr. Barnes's transition to an independent clinical-researcher in the field of obesity.

描述（由申请人提供）：本申请适用于指导患者导向的研究职业发展奖（K23）。候选人 Rachel D. Barnes 博士对多学科团队中超重和肥胖的创新治疗方法以及进一步了解与体重相关的新变量有兴趣。 Barnes 博士计划作为耶鲁大学医学院 (YSM) 的初级教员，获得必要的技能，以成功获得校外资助，并成为肥胖领域的独立临床研究员。该培训和研究计划由 YSM 精神病学教授、耶鲁大学心理学教授、肥胖、体重和饮食研究项目主任 Carlos M. Grilo 博士以及吉林斯公共卫生学院健康行为和健康教育系以及营养系联合任命的副教授 Deborah Tate 博士的专家指导和合作组成。 北卡罗来纳医学院，教堂山。这些导师以及来自 YSM 的国际公认贡献者将协助 Barnes 博士实现并最大化培训和研究计划。 Barnes 博士计划投入至少 75% 的时间来获取与肥胖相关的行为和心理因素以及干预超重和肥胖的进一步知识和专业知识。她为 K23 提出的具体培训发展目标是： 1) 获得在不同环境下评估和干预肥胖的更多专业知识； 2）设计并进行随机临床试验； 3) 获得与改进干预肥胖的临床方法相关的心理学方法的培训和研究。该应用的研究计划由三项相互关联的研究组成，旨在： 1) 在超重和肥胖治疗寻求样本中验证食物思维抑制量表 (FTSI)； 2) 在随机对照试验 (RCT) 中检查暴食症的 FTSI； 3) 开展一项创新性随机对照试验，在初级保健中治疗肥胖症，使用易于获取且经济上可行的互联网治疗，并辅以动机性访谈。总的来说，这些研究将增加 Barnes 博士对进行临床试验的伦理和复杂性（包括统计复杂性和方法）的了解，并将为 R01 应用的开发提供信息。拟议的研究有可能提高我们对治疗肥胖的系统性广泛方法和新颖的体重相关结构的理解。 K23 将支持 Barnes 博士转型为肥胖领域的独立临床研究员。