1/2-Integrative Cognitive Affective Therapy for Binge Eating Disorder

1/2-整合认知情感疗法治疗暴食症

• 批准号: 8726485
• 负责人: CAROL B. PETERSON
• 金额: $ 22.8万
• 依托单位: UNIVERSITY OF MINNESOTA
• 依托单位国家: 美国
• 财政年份: 2013
• 资助国家: 美国
• 起止时间: 2013-08-26 至 2016-06-30
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/8726485
• 关键词: Abstinence; Adherence; Affective; Anxiety; Behavior; Behavioral; Binge Eating; Binge eating disorder; Body mass index; Clinical; Cognition; Cognitive; Cognitive Therapy; DSM-IV; Data; Diagnosis; Diagnostic and Statistical Manual of Mental Disorders; Disease remission; Distress; Eating Behavior; Eating Disorders; Emotions; Evidence based treatment; Frequencies; Hyperphagia; Impairment; Individual; Interview; Laboratories; Maintenance; Measures; Medical; Mental Depression; Modeling; Obesity; Outcome; Outcome Measure; Outpatients; Overweight; Participant; Patient Self-Report; Patients; Pattern; Persons; Physical activity; Pilot Projects; Process; Psychopathology; Psychotherapy; Quality of life; Randomized; Randomized Controlled Trials; Recurrence; Research; Risk Factors; Specific qualifier value; Subgroup; Testing; Treatment Efficacy; Treatment Protocols; Treatment outcome; base; comparative efficacy; depressive symptoms; emotion regulation; follow-up; innovation; public health relevance; secondary outcome; self esteem; self help

DESCRIPTION (provided by applicant): Binge eating disorder (BED) involves recurrent episodes of uncontrolled overeating that cause significant distress and impairment. BED is also considered to be a risk factor for a variety of psychiatric and medical problems, including depression, anxiety, impaired quality of life, obesity, and numerous negative medical outcomes. The present study proposes to compare a new treatment for BED (Integrative Cognitive-Affective Therapy-BED; ICAT-BED) to an evidence based treatment for BED (Cognitive Behavior Therapy-Guided Self- Help; CBTgsh). BED participants will be randomized to one of the two treatment conditions, in which they will receive 17 weeks of outpatient treatment. Participants will be comprehensively assessed at baseline, end of treatment, and 6-month follow-up. In addition, participants will complete Ecological Momentary Assessments (EMA) of eating behavior, emotion, and activity at baseline, end of treatment, and 6-month follow-up. Participants' treatment sessions will be digitally recorded and teams of adherence raters will assess the degree to which clinicians adhered to the treatment protocols. Outcomes will focus on reductions in binge eating behavior and core eating disorder psychopathology, as well as comorbid psychopathology, treatment acceptance, clinical impairment, attrition, body mass index, and physical activity. Hypothesized binge eating maintenance factors including cognitive self-discrepancy will be examined as potential treatment moderators. Data from this project will further clarify the efficacy of ICAT-BED and will provide a test of an underlying conceptual model of BED based on momentary emotion regulation processes.

描述（由申请人提供）：暴食症（BED）涉及反复发作的不受控制的暴饮暴食，导致严重的痛苦和损害。暴食症也被认为是各种精神和医学问题的危险因素，包括抑郁、焦虑、生活质量受损、肥胖和许多负面的医疗结果。本研究拟将 BED 的新疗法（综合认知情感疗法 -BED；ICAT-BED）与基于证据的 BED 疗法（认知行为疗法引导自助；CBTgsh）进行比较。 BED 参与者将被随机分配到两种治疗条件之一，他们将接受 17 周的门诊治疗。参与者将在基线、治疗结束和 6 个月随访时接受全面评估。此外，参与者将在基线、治疗结束和 6 个月随访时完成饮食行为、情绪和活动的生态瞬时评估 (EMA)。参与者的治疗过程将以数字方式记录，依从性评估小组将评估临床医生遵守治疗方案的程度。结果将集中于暴食行为和核心饮食障碍精神病理学的减少，以及共病精神病理学、治疗接受度、临床损伤、损耗、体重指数和体力活动。假设的暴食维持因素，包括认知自我差异，将作为潜在的治疗调节因素进行检查。该项目的数据将进一步阐明 ICAT-BED 的功效，并将提供基于瞬时情绪调节过程的 BED 基本概念模型的测试。