Investigating the role of Kaposi sarcoma herpesvirus Bcl-2 in tumourigenesis

未能通过程序性细胞死亡去除受损，感染或不需要的细胞会导致许多疾病，包括癌症和自身免疫疾病。病毒有能力破坏宿主细胞的死亡机制，为自己谋利益。病毒感染与许多癌症有关。我们的目标是针对病毒破坏细胞死亡过程的能力，以开发针对病毒相关癌症的新疗法，包括卡波西肉瘤或原发性渗出性淋巴瘤。

Failure to remove damaged, infected or unwanted cells via programmed cell death leads to a number of diseases, including cancers and auto-immune diseases. Viruses have the ability to subvert the host cell death machinery for their own benefit. Viral infections have been linked to a number of cancers. We aim to target the ability of viruses to subvert the process of cell death to develop new treatments against virus-linked cancers including Kaposi’s sarcoma or primary effusion lymphoma.