Role of Kaposi sarcoma herpesvirus in tumour development

卡波西肉瘤疱疹病毒在肿瘤发生中的作用

• 批准号: nhmrc : GNT1007918
• 负责人: A/Pr Marc Kvansakul
• 金额: $ 41.46万
• 依托单位: La Trobe University
• 依托单位国家: 澳大利亚
• 项目类别: Project Grants
• 财政年份: 2011
• 资助国家: 澳大利亚
• 起止时间: 2011-01-01 至 无数据
• 项目状态: 已结题
• 来源: https://researchdata.edu.au/role-kaposi-sarcoma-tumour-development/1344258
• 关键词: Role; Kaposi; sarcoma; herpesvirus; tumour

Failure to remove damaged, infected or unwanted cells via programmed cell death leads to a number of diseases, including cancers and auto-immune diseases. Viruses have the ability to subvert the host cell death machinery for their own benefit. Viral infections have been linked to a number of cancers. We aim to target the ability of viruses to subvert the process of cell death to develop new treatments against virus-linked cancers including Kaposi’s sarcoma or primary effusion lymphoma.

未能通过程序性细胞死亡去除受损，感染或不需要的细胞会导致许多疾病，包括癌症和自身免疫疾病。病毒有能力破坏宿主细胞的死亡机制，为自己谋利益。病毒感染与许多癌症有关。我们的目标是针对病毒破坏细胞死亡过程的能力，以开发针对病毒相关癌症的新疗法，包括卡波西肉瘤或原发性渗出性淋巴瘤。