IGF::OT::IGF: Expert Meeting on Assessing and Encouraging Interaction between Gen

IGF::OT::IGF：评估和鼓励Gen 之间互动的专家会议

• 批准号: 8756078
• 负责人: JILL COLLAMORE
• 金额: $ 4.5万
• 依托单位: NATIONAL ACADEMY OF SCIENCES
• 依托单位国家: 美国
• 财政年份: 2013
• 资助国家: 美国
• 起止时间: 2013-09-30 至 2014-09-29
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/8756078
• 关键词: Age; Aging; Alzheimer' s Disease; Area; Behavioral; Behavioral Model; Cognitive; Collaborations; Disease; Fostering; Future; Genetic; Genetic Variation; Health; Interdisciplinary Study; Link; Longitudinal Studies; Outcome; Personal Satisfaction; Phenotype; Population; Relative (related person); Research; Research Personnel; Retirement; Science; Sensory; Wisconsin; behavioral/social science; meetings; social; social model

NIA seek input from a small expert group, organized by Committee on Population (CPOP) and the Board on Behavioral, Cognitive, and Sensory Sciences (BBCSS) on how genetics can inform social and behavioral models in order to foster interdisciplinary research in this area. The recent availability in large longitudinal studies of aging (e.g., the Health and Retirement Study, the English Longitudinal Study of Ageing, and the Wisconsin Longitudinal Study) has afforded the opportunity for researchers to explore the genetic underpinnings of behavioral and social phenotypes that appear to explain differences in health and disease. Higher educational attainment, for example is linked to many important positive health and well-being outcomes, including relative protection from Alzheimer¿s disease. Recently, one large consortium has presented evidence that specific gene variants do explain a small fraction of the variability in educational attainment (Rietveld et al., 2013 Science), but how we will incorporate this and other expected future findings into behavioral and social models is unclear. This NAS activity will help NIA foster new research and collaborations between genetics and behavioral/social science.

NIA寻求一个由人口委员会(CPOP)和行为、认知和感觉科学委员会(BBCS)组织的小型专家组的意见，内容是遗传学如何为社会和行为模型提供信息，以促进这一领域的跨学科研究。最近在大型老龄化纵向研究(例如，健康和退休研究、英国老龄化纵向研究和威斯康星州纵向研究)中的可用性为研究人员提供了机会来探索行为和社会表型的遗传基础，这些表型似乎解释了健康和疾病的差异。例如，较高的教育程度与许多重要的积极健康和福祉结果有关，包括相对预防阿尔茨海默病和S病。最近，一个大型联盟提出了证据，证明特定的基因变异确实可以解释教育程度差异的一小部分(Rietveld等人，2013年《科学》)，但我们如何将这一发现和其他预期的未来发现纳入行为和社交模型尚不清楚。这项NAS活动将帮助NIA促进遗传学和行为/社会科学之间的新研究和合作。