IGF::OT::IGF: Methods for Combining Data from Randomized Controlled Trials and Ob

NIA已经与NAS国家统计委员会签订了一项合同，以了解将RCT数据与观察性研究相结合的方法，这些方法可能会比单独使用任何一种方法提供更明确的分析。NIA支持几项关于老年人口的观察性研究，涵盖许多社会和行为研究领域，包括美国中年(MIDUS)、国家社会生活、健康和老龄化项目(NSHAP)、威斯康星州纵向研究(WLS)、国家健康和老龄化趋势研究(NHATS)以及健康和退休研究(HRS)。NIA促进了一系列基于欧洲、亚洲和拉丁美洲HRS的国际数据集的开发，以利用跨国差异来研究退休对认知和健康的影响等问题。NIA还支持审查大型计划变化或干预措施的准实验研究，例如将联邦医疗保险扩大到涵盖处方药，以及通过在俄勒冈州通过抽奖扩大医疗补助。NIA寻求专家意见，以最大限度地利用这一独特的数据资产集合的效用，这些资产集中在老龄化人口的随机对照试验和自然实验中，用于老龄化方面的社会和行为研究？这次探索性规划会议的范围相对较窄。例如，我们的观测数据(按原样或有少量增加)可以提高随机对照试验关注老龄人口的外部有效性，并有助于更好地聚焦实验或干预计划。

NIA has entered into a contract with the NAS Committee on National Statistics to learn about methods for combining data from RCTs and observational studies that could potentially offer more definitive analyses than either method alone. NIA supports several observational studies on older populations covering many social and behavioral research domains including the Midlife in the United States (MIDUS), the National Social Life, Health and Aging Project (NSHAP), the Wisconsin Longitudinal Study (WLS), the National Health and Aging Trends Study (NHATS), and the Health and Retirement Study (HRS). NIA has fostered the development of a collection of international data sets based on the HRS in Europe, Asia, and Latin America to exploit cross-national differences to study questions such as the impact of retirement on cognition and health. NIA also supports quasi-experimental research examining large program changes or interventions such as the expansion of Medicare to cover prescription drugs and Medicaid expansion via lottery in Oregon. NIA seek expert input on how to maximize the utility of this unique collection of data assets that focus on aging populations with RCTs as well as natural experiments for social and behavioral research in aging ¿ a relatively narrow scope for this exploratory planning meeting. For example, our observational data (as is or with minor additions) could improve external validity of RCTs focusing on aging populations and can help better focus plans for experiments or interventions.