NIA IRP Comparative Medicine Section

NIA IRP 比较医学部分

• 批准号: 8736979
• 负责人: Luigi Ferrucci
• 金额: $ 411.99万
• 依托单位: NATIONAL INSTITUTE ON AGING
• 依托单位国家: 美国
• 资助国家: 美国
• 起止时间: 至
• 项目状态: 未结题
• 来源: https://reporter.nih.gov/project-details/8736979
• 关键词: Accreditation; Animal Care and Use Committees; Animal Experimentation; Animal Housing; Animal Welfare; Animals; Area; Behavioral Research; Biomedical Research; Caring; Chairperson; Educational process of instructing; Ensure; Future; Genetic; Guidelines; Housing; International; Laboratory Animals; Medicine; Mission; Mus; Personal Satisfaction; Procedures; Regulation; Research; Research Personnel; Research Support; Resources; Scientist; Site; Testing; Training; United States National Institutes of Health; Update; Work; animal care; comparative; meetings; programs

The CMS supports the research of NIA scientists. A critical focus of this support is training in the humane care and handling of research animals. CMS is responsible for housing and care of research animals and for ensuring their well-being. The animal program and animal laboratory areas are inspected and evaluated at least twice each year by the NIA Animal Care and Use Committee (ACUC), in compliance with federal regulations and guidelines. CMS works to establish firm and consistent resource management while enhancing a collaborative relationship with investigators. These efforts are critical to insure the optimal use of available resources while meeting the needs of the investigators. The training offered through NIA CMS ensures that all animal handling is in compliance with NIA, NIH, and federal regulations and guidelines for the continued assurance of full accreditation by the Association for the Assessment and Accreditation of Laboratory Animal Care, International (AAALACi). The NIA CMS also develops and/or recommends refinements in humane care and handling and provides training to NIA intramural researchers. All NIA research staff using animals are required to complete facility-specific training. This training includes requirements for facility entry, proper animal handling procedures, and other related issues. The NIA APD and ACUC Chairperson also provide updates on new/revised Federal, NIH, and/or NIA animal welfare guidelines at monthly NIA meetings. The BRC animal holding area was renovated and all animals housed in the GRC were moved into the renovated space. The GRC facility was abandoned. Every three years the NIA animal program is assessed by the accrediting organization AAALACi. AAALACi site visitors toured the BRC in July 2013. The NIA animal program accreditation status is awaiting the decision of the AAALAC Council on Accreditation but full continuing accreditation is expected. CMS continues to cryopreserve important mouse lines. Twenty mouse lines were cryopreserved this year, removing animals from the program while conserving their unique genetics for future use.

CMS支持NIA科学家的研究。这种支持的一个关键重点是在人道关怀和处理研究动物的培训。CMS负责研究动物的饲养和护理，并确保其健康。根据联邦法规和指南，NIA动物护理和使用委员会（ACUC）每年至少对动物项目和动物实验室区域进行两次检查和评价。CMS致力于建立坚定和一致的资源管理，同时加强与调查人员的合作关系。这些努力对于确保最佳利用现有资源，同时满足调查人员的需要至关重要。 通过NIA CMS提供的培训确保所有动物处理均符合NIA、NIH和联邦法规和指南，以持续确保获得国际实验动物评估和认可协会（AAALACi）的全面认可。NIA CMS还开发和/或建议人道主义护理和处理的改进，并为NIA内部研究人员提供培训。 所有使用动物的NIA研究人员都必须完成机构特定的培训。该培训包括进入设施的要求、适当的动物处理程序和其他相关问题。NIA APD和ACUC主席还在每月的NIA会议上提供关于新的/修订的联邦、NIH和/或NIA动物福利指南的更新。 对BRC动物饲养区进行了翻新，将饲养在GRC中的所有动物移入翻新空间。 GRC设施已被废弃。 每三年，NIA的动物项目都会由认证组织AAALACi进行评估。 2013年7月，AAALACI网站访问者参观了布拉迪斯拉发区域中心。 NIA动物项目的认证状态正在等待AAALAC理事会的认证决定，但预计将获得全面的持续认证。 CMS继续冷冻保存重要的小鼠品系。 今年有20个小鼠品系被冷冻保存，将动物从该计划中删除，同时保留其独特的遗传基因供未来使用。