Midcareer Investigator Award in Patient-Oriented Research

以患者为导向的研究中的职业生涯中期研究员奖

• 批准号: 8465168
• 负责人: MARK STEVEN LACHS
• 金额: $ 16.38万
• 依托单位: WEILL MEDICAL COLL OF CORNELL UNIV
• 依托单位国家: 美国
• 财政年份: 2003
• 资助国家: 美国
• 起止时间: 2003-09-01 至 2016-04-30
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/8465168
• 关键词: Achievement; Aging; Area; Assisted Living Facilities; Award; Collaborations; Comorbidity; Data Set; Elder Abuse; Elderly; Fellowship; Foundations; Funding; Geriatrics; Grant; Homes for the Aged; Individual; Institution; Interest Group; Meals on Wheels; Medical Students; Mentors; Mentorship; Midcareer Investigator Award in Patient-Oriented Research; National Institute of Mental Health; Nursing Homes; Parents; Physicians; Pilot Projects; Principal Investigator; Process; Psychiatrist; Publications; Recording of previous events; Research; Research Activity; Research Personnel; Resources; Role; Scientist; Sister; Structure; Students; Supplementation; Training; United States National Institutes of Health; Universities; Vitamin D; arm; career; career development; elder neglect; geriatric depression; investigator training; medical schools; multidisciplinary; next generation; patient oriented research; programs; public health relevance

DESCRIPTION (provided by applicant): This is an application for renewal of a K24 mentoring award in patient oriented research in aging from Mark Lachs MD MPH of the Weill Cornell Medical College. The immediate objectives of the program are (1) to extend the candidate's successful program of mentorship created in the first cycle to trainees at Columbia University in collaboration with Dr. Linda Fried in any mentee-directed area of aging research (the local program), and (2) to create a national mentorship program for junior investigators in the field of elder abuse (the national program). Both initiatives derive from barriers identified in the first cycle which hamper career development of two specific mentee constituencies. In the case of the proposed local program, the world renowned aging research activities of Columbia University have not yet highly impacted its Division of Geriatric Medicine. In the case of the proposed national program, dearth of highly trained investigators in the field of elder abuse who can mentor the next generation of researchers is a dire concern; Dr. Lachs is the only physician-scientist in the history of NIH to hold an RO1 in the field, a requirement of the K24 mechanism. Over the course of the first K24 cycle, the candidate was contacted regularly by trainees of both types desirous of mentorship; this renewal formalizes that process while continuing to serve the steady pool of potential mentees created by the original program. Notable achievements in the first cycle include: the mentorship of 24 trainees at all levels who coauthored multiple publications with the PI and received many federal and foundation grants, renewal of the parent RO1 - the largest elder abuse grant in the history of NIA to study resident to resident elder mistreatment (RREM) in nursing homes, the acquisition of three other major grants to the PI which will serve as a resource for mentees, and the acquisition or renewal of several major center grants at Cornell (with which the PI assisted) that have pilot programs and other resources than can assist mentees nationally and locally. These include an NIA funded Roybal Center (led by former mentee Dr. Cary Reid), renewal of an NIMH Geriatric Depression Center (led by longstanding collaborator Dr. George Alexopolous), and a CTSC (led by fellow Division Chief Dr. Julianne Imperato-McGinley). Three pilot projects involving mentees at different levels in both arms of the program are proposed for the initial year: (1) A study of Vitamin D supplementation in meals on wheels recipients by Columbia geriatrician Dr. Tien Dam (local program), (2) A study of psychiatric co-morbidity in RREM by University of Rochester Geriatric Psychiatrist EJ Santos (national program), and (3) a study of RREM in assisted living facilities by Cornell ED Resident Anthony Rosen (local program). The PI has made data sets and/or research resources available for each project, emblematic how subsequent mentoring will be structured. An additional strength of the application is co-mentorship from Dr. Lachs' colleague Dr. Jeanne Teresi and her research group at the Hebrew Home for the Aged. A psychometrician and statistician, Dr. Teresi is a collaborating investigator all his current projects, and has mentored over 200 individuals in aging research. The Long Term Objectives of the K24 program are (1) to more fully integrate patient oriented research in aging at Cornell and Columbia, thereby inciting more trainees to select careers in aging research, and (2) to create a self-sustaining cadre of researchers who conduct patient oriented research in elder abuse. The overarching and longest term objective for both the national and local programs is that they ultimately be self-sustaining and independent of the candidate, as mentees take on mentor roles.

描述（由申请人提供）：这是续签Weill Cornell医学院Mark Lachs MD MPH的衰老中K24指导奖的申请。该计划的直接目标是（1）将候选人在第一个周期中创建的成功指导计划扩展到哥伦比亚大学的学员，并与琳达博士在任何受训者指导的老龄化研究领域（本地计划）中合作，以及为年轻虐待领域的初级调查人员（国家计划）创建一项国家指导计划（国家计划）。这两项举措均来自第一个周期中确定的障碍，这阻碍了两个特定的训练者选区的职业发展。就拟议的本地计划而言，哥伦比亚大学著名的衰老研究活动尚未对其老年医学部门产生重大影响。就拟议的国家计划而言，虐待老年训练的调查员的缺乏，可以指导下一代研究人员，这是一个可怕的问题。 Lachs博士是NIH历史上唯一在现场持有RO1的医师科学家，这是K24机制的要求。在第一个K24周期的过程中，两种类型的学员定期与候选人联系。这种续约使该过程正式化，同时继续为原始计划创造的稳定的潜在受训者库。第一个周期中的显着成就包括：在各个层面上的24名学员的指导，他们与PI合着了多个出版物，并获得了许多联邦和基金会的赠款，对父母RO1的续签（NIA历史上最大的老年人虐待授予居住在居住的NIA历史上最大的虐待赠款），居住在居民中的居民虐待（RREM），这是PIE的供应，并将其作为托管供应，并作为托儿所的供应，并将作为托儿所或其他供应。续签了康奈尔（PI协助）拥有试点计划和其他资源的几项主要中心补助金，而不是可以在全国和本地协助受训者。其中包括一个由NIA资助的Roybal中心（由前受训者Cary Reid博士领导），NIMH老年抑郁症中心（由长期合作者George Alexopolous博士领导）和CTSC（由CTSC领导的CTSC（由朱利安·尤利安·伊普吉·麦金利（Julianne Imperato-Mcginley）博士领导））。首先提出了三个计划的试点项目，该项目涉及该计划的两个臂的不同级别：（1）哥伦比亚老年医生Tien Dam博士（本地计划）对餐的饮食中维生素D补充的研究，（2）Rochester Anative and Control（2）Rochester Anational and Control ochester a Preshitial and cossialtric and gerrem cossitialtric and geriatric of（3） RREM在康奈尔·埃德（Cornell Ed）居民安东尼·罗森（Anthony Rosen）（本地计划）的辅助生活设施中。 PI已为每个项目提供了可用的数据集和/或研究资源，并象征着如何进行随后的指导。该申请的额外优势是Lachs博士的同事Jeanne Teresi博士和她在希伯来语中的研究小组的会议。 Teresi博士是一名心理学家和统计学家，是他目前的所有项目的合作调查员，并指导了200多名老龄化研究。 K24计划的长期目标是（1）更充分地整合康奈尔和哥伦比亚的衰老研究，从而煽动更多的学员选择老龄化研究中的职业，以及（2）创建一个自我维持的研究人员，这些研究人员从事以患者为导向的老年虐待研究的研究人员。国家和地方计划的总体和最长的目标是，正如受训者扮演导师的角色一样，它们最终是自我维持的，并且独立于候选人。