Midcareer Investigator Award in Patient-Oriented Research

以患者为导向的研究中的职业生涯中期研究员奖

• 批准号: 8465168
• 负责人: MARK STEVEN LACHS
• 金额: $ 16.38万
• 依托单位: WEILL MEDICAL COLL OF CORNELL UNIV
• 依托单位国家: 美国
• 财政年份: 2003
• 资助国家: 美国
• 起止时间: 2003-09-01 至 2016-04-30
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/8465168
• 关键词: Achievement; Aging; Area; Assisted Living Facilities; Award; Collaborations; Comorbidity; Data Set; Elder Abuse; Elderly; Fellowship; Foundations; Funding; Geriatrics; Grant; Homes for the Aged; Individual; Institution; Interest Group; Meals on Wheels; Medical Students; Mentors; Mentorship; Midcareer Investigator Award in Patient-Oriented Research; National Institute of Mental Health; Nursing Homes; Parents; Physicians; Pilot Projects; Principal Investigator; Process; Psychiatrist; Publications; Recording of previous events; Research; Research Activity; Research Personnel; Resources; Role; Scientist; Sister; Structure; Students; Supplementation; Training; United States National Institutes of Health; Universities; Vitamin D; arm; career; career development; elder neglect; geriatric depression; investigator training; medical schools; multidisciplinary; next generation; patient oriented research; programs; public health relevance

DESCRIPTION (provided by applicant): This is an application for renewal of a K24 mentoring award in patient oriented research in aging from Mark Lachs MD MPH of the Weill Cornell Medical College. The immediate objectives of the program are (1) to extend the candidate's successful program of mentorship created in the first cycle to trainees at Columbia University in collaboration with Dr. Linda Fried in any mentee-directed area of aging research (the local program), and (2) to create a national mentorship program for junior investigators in the field of elder abuse (the national program). Both initiatives derive from barriers identified in the first cycle which hamper career development of two specific mentee constituencies. In the case of the proposed local program, the world renowned aging research activities of Columbia University have not yet highly impacted its Division of Geriatric Medicine. In the case of the proposed national program, dearth of highly trained investigators in the field of elder abuse who can mentor the next generation of researchers is a dire concern; Dr. Lachs is the only physician-scientist in the history of NIH to hold an RO1 in the field, a requirement of the K24 mechanism. Over the course of the first K24 cycle, the candidate was contacted regularly by trainees of both types desirous of mentorship; this renewal formalizes that process while continuing to serve the steady pool of potential mentees created by the original program. Notable achievements in the first cycle include: the mentorship of 24 trainees at all levels who coauthored multiple publications with the PI and received many federal and foundation grants, renewal of the parent RO1 - the largest elder abuse grant in the history of NIA to study resident to resident elder mistreatment (RREM) in nursing homes, the acquisition of three other major grants to the PI which will serve as a resource for mentees, and the acquisition or renewal of several major center grants at Cornell (with which the PI assisted) that have pilot programs and other resources than can assist mentees nationally and locally. These include an NIA funded Roybal Center (led by former mentee Dr. Cary Reid), renewal of an NIMH Geriatric Depression Center (led by longstanding collaborator Dr. George Alexopolous), and a CTSC (led by fellow Division Chief Dr. Julianne Imperato-McGinley). Three pilot projects involving mentees at different levels in both arms of the program are proposed for the initial year: (1) A study of Vitamin D supplementation in meals on wheels recipients by Columbia geriatrician Dr. Tien Dam (local program), (2) A study of psychiatric co-morbidity in RREM by University of Rochester Geriatric Psychiatrist EJ Santos (national program), and (3) a study of RREM in assisted living facilities by Cornell ED Resident Anthony Rosen (local program). The PI has made data sets and/or research resources available for each project, emblematic how subsequent mentoring will be structured. An additional strength of the application is co-mentorship from Dr. Lachs' colleague Dr. Jeanne Teresi and her research group at the Hebrew Home for the Aged. A psychometrician and statistician, Dr. Teresi is a collaborating investigator all his current projects, and has mentored over 200 individuals in aging research. The Long Term Objectives of the K24 program are (1) to more fully integrate patient oriented research in aging at Cornell and Columbia, thereby inciting more trainees to select careers in aging research, and (2) to create a self-sustaining cadre of researchers who conduct patient oriented research in elder abuse. The overarching and longest term objective for both the national and local programs is that they ultimately be self-sustaining and independent of the candidate, as mentees take on mentor roles.

描述（由申请人提供）：这是威尔康奈尔医学院 Mark Lachs MD MPH 提出的续签 K24 指导奖的申请，该奖项涉及以患者为导向的衰老研究。该计划的直接目标是（1）与琳达·弗里德博士合作，将候选人在第一轮中创建的成功指导计划扩展到哥伦比亚大学的受训者，在任何受指导者指导的老龄化研究领域（当地计划），以及（2）为虐待老年人领域的初级研究人员创建一个国家指导计划（国家计划）。这两项举措都源于第一周期中发现的阻碍两个特定受训者群体职业发展的障碍。就拟议的本地项目而言，哥伦比亚大学世界著名的衰老研究活动尚未对其老年医学部门产生重大影响。就拟议的国家计划而言，虐待老年人领域缺乏训练有素的调查人员来指导下一代研究人员，这是一个令人担忧的问题； Lachs 博士是 NIH 历史上唯一一位拥有该领域 RO1 资格的医师兼科学家，这是 K24 机制的要求。在第一个 K24 周期的过程中，两类学员定期联系候选人并寻求指导；此次更新使该流程正式化，同时继续为原始计划创建的稳定的潜在受训者群体提供服务。第一个周期的显着成就包括：对 24 名各级学员的指导，他们与 PI 共同撰写了多篇出版物，并获得了许多联邦和基金会拨款；续签了母公司 RO1——NIA 历史上最大的虐待老年人拨款，用于研究疗养院中居民之间的虐待老人（RREM）；为 PI 获得了其他三项主要拨款，作为受训者的资源；以及获得或 更新康奈尔大学的几个主要中心赠款（PI 协助的），这些赠款拥有试点项目和其他资源，可以帮助全国和当地的受训者。其中包括 NIA 资助的 Roybal 中心（由前学员 Cary Reid 博士领导）、更新的 NIMH 老年抑郁症中心（由长期合作者 George Alexopolous 博士领导）和 CTSC（由部门主管 Julianne Imperato-McGinley 博士领导）。第一年提出了三个试点项目，涉及该计划两个部门不同级别的受训者：(1) 哥伦比亚老年病学家 Tien Dam 博士进行的一项关于在轮餐接受者中补充维生素 D 的研究（当地计划），(2) 罗切斯特大学老年精神病学家 EJ Santos 进行的一项关于 RREM 精神共病的研究（国家计划），以及 (3) 一项关于 RREM 精神共病的研究 康奈尔大学 ED 住院医师 Anthony Rosen 在辅助生活设施中实施 RREM（当地计划）。 PI 为每个项目提供了可用的数据集和/或研究资源，这象征着后续指导将如何构建。该应用程序的另一个优势是 Lachs 博士的同事 Jeanne Teresi 博士及其在希伯来老人之家的研究小组的共同指导。 Teresi 博士是一名心理测量学家和统计学家，也是他当前所有项目的合作调查员，并指导了 200 多名衰老研究人员。 K24项目的长期目标是（1）更全面地整合康奈尔大学和哥伦比亚大学以患者为导向的老龄化研究，从而激励更多的学员选择老龄化研究职业，以及（2）建立一支自我维持的研究人员队伍，在虐待老年人问题上进行以患者为导向的研究。国家和地方项目的总体和长期目标是，当受训者扮演导师的角色时，它们最终能够自我维持并独立于候选人。