Web and Mobile Smoking Cessation Interventions

网络和移动戒烟干预措施

• 批准号: 8418100
• 负责人: Brian G. Danaher
• 金额: $ 64.55万
• 依托单位: OREGON RESEARCH INSTITUTE
• 依托单位国家: 美国
• 财政年份: 2013
• 资助国家: 美国
• 起止时间: 2013-03-21 至 2017-02-28
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/8418100
• 关键词: Abstinence; Adult; American; Behavior; Car Phone; Characteristics; Communication Aids for Disabled; Consumer Satisfaction; Demographic Factors; Development; Devices; Enrollment; Evaluation; Frequencies; Health behavior change; Indium; Individual; Internet; Intervention; Measures; Mediating; Mediator of activation protein; Meta-Analysis; Methods; Modality; Nicotine Dependence; Online Systems; Outcome; Participant; Persuasive Communication; Play; Policies; Prevalence; Process; Public Health; Randomized; Recommendation; Research; Science; Self Efficacy; Smoker; Smoking; Smoking Cessation Intervention; Solutions; System; Technology; Telephone; Testing; Text; Time; Tobacco; Tobacco Use Cessation; Tobacco use; Treatment Efficacy; Treatment outcome; Voice; Withholding Treatment; arm; comparative efficacy; cost; cost effectiveness; evidence base; follow-up; improved; innovation; primary outcome; programs; public health relevance; response; smoking cessation; tobacco abstinence; treatment program; web site

DESCRIPTION (provided by applicant): Web-based health behavior change interventions - including smoking cessation programs - offer great promise but in many cases their absolute efficacy is diminished because many participants often spend relatively little time accessing program content. One potential solution involves adding treatment components that are delivered to participants' mobile phones. More than 90% of Americans use mobile phones and most keep their phones in close proximity throughout the day. As a result, these mobile devices can provide just in time assistance when it is most needed and they are proactive in that they reach out to users to deliver content and to increase its utilization and salience. Objectives: We propose a controlled test assessing tobacco abstinence associated with an adjunctive Mobile intervention combined with a best-practices Web-based smoking cessation intervention. We hypothesize that this Web Mobile approach will yield greater efficacy than a Web Only condition. Methods: We propose a 2-arm RCT with 2,260 adult study participants randomized to a Web Mobile or a Web Only condition. Because the central question is whether the combined Web Mobile approach improves efficacy, both conditions use a very similar best-practices core website that embodies many of the features found in the enhanced interventions tested in our prior Web-based tobacco cessation trials. The mobile modalities include automated text messages (SMS) and automated phone calls (IVR or Interactive Voice Response). Measures: Our primary outcome is sustained tobacco abstinence operationally defined as no tobacco use during the interval defined from the 3-month assessment to the 6-month assessment. At both the 3- and 6- month follow-up assessments we measure 7- and 30-day point prevalence tobacco abstinence. We also compare the intervention cost and incremental cost-effectiveness (cost per-participant and cost per-quit) of each experimental condition. Ancillary analyses will examine potential predictors, moderators, and putative mediators (i.e., self-efficacy, program use, use of pharmacological adjuncts). Benefits: To the best of our knowledge, this application describes the first RCT that assesses the incremental efficacy of adding Mobile components to a Web-based smoking cessation intervention. Evaluating the value of adding Mobile components to a Web intervention will have substantial public health impact because such interventions are able to cost-effectively reach many smokers who want to quit. The research will also advance the emerging science of Web Mobile interventions by seeking to identify beneficial adjunctive mechanisms.

描述（由申请人提供）：基于网络的健康行为改变干预措施-包括戒烟计划-提供了很大的希望，但在许多情况下，它们的绝对功效被削弱，因为许多参与者通常花费相对较少的时间访问计划内容。一个潜在的解决方案涉及添加被递送到参与者的移动的电话的治疗组件。超过90%的美国人使用移动的手机，大多数人整天都把手机放在附近。因此，这些移动的设备可以在最需要的时候提供及时的帮助，并且它们是主动的，因为它们接触用户以递送内容并增加其利用率和显著性。目的：我们提出了一个对照试验，评估与连续性移动的干预结合最佳实践的基于Web的戒烟干预相关的戒烟。我们假设这种Web移动的方法将比仅Web条件产生更大的功效。方法：我们提出了一项2组RCT，2，260名成人研究参与者被随机分配到Web移动的或仅Web条件下。因为核心问题是结合Web移动的方法是否能提高疗效，这两种情况都使用了非常相似的最佳实践核心网站，该网站体现了我们之前基于Web的戒烟试验中测试的增强干预措施中发现的许多功能。移动的形式包括自动文本消息（SMS）和自动电话呼叫（IVR或交互式语音应答）。措施：我们的主要结果是持续戒烟，操作上定义为从3个月评估到6个月评估的时间间隔内没有烟草使用。在3个月和6个月的随访评估中，我们测量了7天和30天的戒烟率。我们还比较了每种实验条件的干预成本和增量成本效益（每参与者成本和每退出成本）。辅助分析将检查潜在的预测因子、调节因子和推定的介导因子（即，自我效能、程序使用、药理学药物的使用）。优点：据我们所知，本申请描述了第一项RCT，该RCT评估了将移动的组件添加到基于Web的戒烟干预中的增量疗效。评估将移动的组件添加到Web干预的价值将产生重大的公共卫生影响，因为这种干预能够以成本效益的方式接触到许多想要戒烟的吸烟者。该研究还将通过寻求确定有益的预防机制来推进新兴的网络移动的干预科学。