PancreasFest 2014: Risks and Mechanisms of Pancreatitis and Pancreatic Diabetes

PancreasFest 2014：胰腺炎和胰腺糖尿病的风险和机制

• 批准号: 8785781
• 负责人: DAVID Clement WHITCOMB
• 金额: $ 1.5万
• 依托单位: UNIVERSITY OF PITTSBURGH AT PITTSBURGH
• 依托单位国家: 美国
• 财政年份: 2014
• 资助国家: 美国
• 起止时间: 2014-07-01 至 2015-06-30
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/8785781
• 关键词: Academic Medical Centers; Acute; Address; Adult; Alcoholic Pancreatitis; Alcohols; American; Anniversary; Area; Biological Markers; Caring; Child; Childhood; Chronic; Clinical; Clinical Research; Clinical Trials; Cystic Fibrosis; Cystic Fibrosis Transmembrane Conductance Regulator; Development; Diabetes Mellitus; Diagnosis; Digestive System Disorders; Disease; Early Diagnosis; Education; Educational workshop; Endocrinologist; Ensure; Environmental Risk Factor; Epidemiologist; Event; Faculty; Fibrosis; Fostering; Foundations; Genes; Genetic; Genetic Risk; Goals; Human; Indium; Industry; Inflammation; International; Junior Physician; Learning; Lesion; Malignant neoplasm of pancreas; Mentors; Methods; Molecular; Monitor; Multicenter Studies; National Institute of Diabetes and Digestive and Kidney Diseases; Natural History; Neurobiology; Neurogenic Inflammation; Pain; Pancreas; Pancreatic Diseases; Pancreatic Ductal Adenocarcinoma; Pancreatic Injury; Pancreatitis; Pathogenesis; Patients; Physicians; Prevention; Recommendation; Recurrence; Research; Research Personnel; Research Priority; Research Training; Risk; Risk Marker; Role; Scientist; Surgeon; System; Therapeutic Intervention; Time; Translational Research; Translations; Underrepresented Minority; Universities; Woman; Work; acute pancreatitis; afferent nerve; anticancer research; autoimmune pancreatitis; career development; chronic pancreatitis; clinical care; clinical epidemiology; clinical practice; follow-up; interest; macrophage; meetings; next generation; population based; prevent; programs; public health relevance; radiologist; repaired; research study; symposium; translational study; working group

DESCRIPTION (provided by applicant): Advancing our understanding of human pancreatic diseases, especially acute and chronic pancreatitis, requires the cooperative effort of a network of clinical centers of excellence and the regular meeting of thought leaders in the field. The course objectives for PancreasFest 2014: Risks and Mechanisms of Pancreatitis and Pancreatic Diabetes, will enhance progress on meeting research priorities highlighted by the National Commission of Digestive Diseases. Specifically, we will 1) Critically review genetic and environmental risk factors associated with development of pancreatitis and pancreatic fibrosis and pancreatic pain; 2); Critically review origin and progression of pancreatic (Type 3c) diabetes and its relationship to pancreatic ductal adenocarcinoma; and 3) Discuss strategies for translation of new scientific discoveries into clinical trials and practice, including needs analyss and criteria for defining standards of care. The University of Pittsburgh has organized and hosted PancreasFest and its precursors since 1994. No other conference in the US focuses exclusively on fostering translational multi-center research programs for pancreatic disorders. Attendees of past meetings uniformly praise PancreasFest for fostering collaborative research and emphasize the importance of having a small conference focused on pancreatic disorders. Multiple clinical working groups that focus on areas of NIDDK interest have emerged over the years through PancreasFest. Typically 130-150 diverse professionals register for PancreasFest each year, including physicians and scientists with interest in the pancreas: pancreatologists, endoscopists, endocrinologists, surgeons, radiologists, molecular biologists, geneticists, epidemiologists, statisticians, systems biologists, and experts in biomarkers. We emphasize attendance by new faculty and fellows to ensure the next generation of pancreatic investigators works directly with and learns from senior researchers in the field. Key staff from the NIDDK are invited to provide perspective and discuss priorities. PancreasFest is also attended by representatives from industry and patient-focused foundations, such as the National Pancreas Foundation. PancreasFest 2014 will be held on the campus of the University of Pittsburgh, Pittsburgh, PA at the University Club on July 23-25, 2014. The NIDDK-sponsored sessions will be part of a larger event, which includes a CME course and the annual meetings of the North American Pancreatic Study Groups, the International Study Group of Pediatric Pancreatitis: In search for a cure (INSPPIRE), and the Collaborative Alliance for Pancreatic Education and Research (CAPER), which is devoted to enhancing the career development of junior physician scientists in the field of pancreatology.

描述（由申请人提供）：推进我们对人类胰腺疾病，特别是急性和慢性胰腺炎的理解，需要临床卓越中心网络的合作努力和该领域思想领袖的定期会议。PancreasFest 2014年的课程目标：胰腺炎和胰腺糖尿病的风险和机制，将促进国家消化疾病委员会强调的研究优先事项的进展。具体而言，我们将1）严格审查与胰腺炎和胰腺纤维化和胰腺疼痛发展相关的遗传和环境风险因素; 2）严格审查胰腺（3c型）糖尿病的起源和进展及其与胰腺导管腺癌的关系;和3）讨论将新的科学发现转化为临床试验和实践的策略，包括需求分析和确定护理标准的标准。匹兹堡大学自1994年以来一直组织和主办PancreasFest及其前身。在美国没有其他会议专门关注促进胰腺疾病的转化多中心研究计划。过去会议的与会者一致赞扬胰腺节促进合作研究，并强调有一个小型会议的重要性，重点是胰腺疾病。多年来，通过PancreasFest，出现了多个专注于NIDDK感兴趣领域的临床工作组。通常每年有130-150名不同的专业人士注册PancreasFest，包括对胰腺感兴趣的医生和科学家：胰腺学家，内窥镜学家，内分泌学家，外科医生，放射学家，分子生物学家，遗传学家，流行病学家，统计学家，系统生物学家和生物标志物专家。我们强调新教师和研究员的出席，以确保下一代胰腺研究人员直接与该领域的高级研究人员合作并向他们学习。邀请NIDDK的主要工作人员提供观点并讨论优先事项。PancreasFest也有来自行业和以患者为中心的基金会的代表参加，如国家胰腺基金会。PancreasFest 2014将于2014年7月23日至25日在宾夕法尼亚州匹兹堡大学的校园内的大学俱乐部举行。NIDDK赞助的会议将是一个更大的活动的一部分，其中包括CME课程和北美胰腺研究组，儿童胰腺炎国际研究组的年度会议：寻找治愈方法（INSPPIRE）和胰腺教育与研究合作联盟（CAPER），致力于加强胰腺病学领域初级医生科学家的职业发展。