PancreasFest 2014: Risks and Mechanisms of Pancreatitis and Pancreatic Diabetes

描述(申请人提供)：促进我们对人类胰腺疾病，特别是急性和慢性胰腺炎的了解，需要临床卓越中心网络的合作努力和该领域思想领袖的定期会议。2014年胰腺节的课程目标：胰腺炎和胰腺糖尿病的风险和机制，将促进在满足国家消化疾病委员会强调的研究优先事项方面取得进展。具体地说，我们将1)严格审查与胰腺炎、胰腺纤维化和胰腺疼痛相关的遗传和环境风险因素；2)严格审查胰腺(3c型)糖尿病的起源和发展及其与胰腺导管腺癌的关系；以及3)讨论将新的科学发现转化为临床试验和实践的策略，包括需求分析和确定护理标准的标准。匹兹堡大学自1994年以来一直组织和主办PancreasFest及其前身。在美国，没有其他会议专门关注促进胰腺疾病的翻译性多中心研究计划。过去会议的与会者一致赞扬PancreasFest促进了合作研究，并强调了举办一次专注于胰腺疾病的小型会议的重要性。多年来，通过PancreasFest，出现了多个专注于NIDDK感兴趣领域的临床工作组。通常每年有130-150名不同的专业人士注册参加胰腺节，包括对胰腺感兴趣的内科医生和科学家：胰腺科医生、内窥镜医生、内分泌科医生、外科医生、放射科医生、分子生物学家、遗传学家、流行病学家、统计学家、系统生物学家和生物标志物专家。我们强调新的教员和研究员的出席，以确保下一代胰腺研究人员直接与该领域的资深研究人员合作并向他们学习。邀请NIDDK的主要工作人员提供观点并讨论优先事项。参加PancreasFest的还有来自行业和以患者为中心的基金会的代表，如国家胰腺基金会。2014年胰腺节将于2014年7月23日至25日在宾夕法尼亚州匹兹堡大学的大学俱乐部举行。NIDDK赞助的会议将是一个更大活动的一部分，该活动包括一个继续医学教育课程和北美胰腺研究小组、儿科胰腺炎国际研究小组：寻求治疗(INSPPIRE)和胰腺教育与研究合作联盟(CAPER)的年度会议，该联盟致力于促进胰腺科学领域初级内科科学家的职业发展。

DESCRIPTION (provided by applicant): Advancing our understanding of human pancreatic diseases, especially acute and chronic pancreatitis, requires the cooperative effort of a network of clinical centers of excellence and the regular meeting of thought leaders in the field. The course objectives for PancreasFest 2014: Risks and Mechanisms of Pancreatitis and Pancreatic Diabetes, will enhance progress on meeting research priorities highlighted by the National Commission of Digestive Diseases. Specifically, we will 1) Critically review genetic and environmental risk factors associated with development of pancreatitis and pancreatic fibrosis and pancreatic pain; 2); Critically review origin and progression of pancreatic (Type 3c) diabetes and its relationship to pancreatic ductal adenocarcinoma; and 3) Discuss strategies for translation of new scientific discoveries into clinical trials and practice, including needs analyss and criteria for defining standards of care. The University of Pittsburgh has organized and hosted PancreasFest and its precursors since 1994. No other conference in the US focuses exclusively on fostering translational multi-center research programs for pancreatic disorders. Attendees of past meetings uniformly praise PancreasFest for fostering collaborative research and emphasize the importance of having a small conference focused on pancreatic disorders. Multiple clinical working groups that focus on areas of NIDDK interest have emerged over the years through PancreasFest. Typically 130-150 diverse professionals register for PancreasFest each year, including physicians and scientists with interest in the pancreas: pancreatologists, endoscopists, endocrinologists, surgeons, radiologists, molecular biologists, geneticists, epidemiologists, statisticians, systems biologists, and experts in biomarkers. We emphasize attendance by new faculty and fellows to ensure the next generation of pancreatic investigators works directly with and learns from senior researchers in the field. Key staff from the NIDDK are invited to provide perspective and discuss priorities. PancreasFest is also attended by representatives from industry and patient-focused foundations, such as the National Pancreas Foundation. PancreasFest 2014 will be held on the campus of the University of Pittsburgh, Pittsburgh, PA at the University Club on July 23-25, 2014. The NIDDK-sponsored sessions will be part of a larger event, which includes a CME course and the annual meetings of the North American Pancreatic Study Groups, the International Study Group of Pediatric Pancreatitis: In search for a cure (INSPPIRE), and the Collaborative Alliance for Pancreatic Education and Research (CAPER), which is devoted to enhancing the career development of junior physician scientists in the field of pancreatology.