Rapid and On-site Monitoring of Urinary Arsenic Metabolites
尿砷代谢物的快速现场监测
基本信息
- 批准号:8714940
- 负责人:
- 金额:$ 51.05万
- 依托单位:
- 依托单位国家:美国
- 项目类别:
- 财政年份:2012
- 资助国家:美国
- 起止时间:2012-09-19 至 2016-05-31
- 项目状态:已结题
- 来源:
- 关键词:AcidsAlgorithmsArchivesArsenatesArsenicArsenitesBiological MarkersBiological MonitoringCacodylic AcidCardiovascular DiseasesChelating AgentsChemicalsChronicCollaborationsCommunicationComputer softwareComputersData AnalysesDetectionDevelopmentDevicesDiagnosticElectrodesElectronicsElementsEnsureEpidemiologic StudiesEvaluationExcisionExposure toFiltrationFoodGeometryGoalsGoldHealthHeavy MetalsHigh Pressure Liquid ChromatographyMalignant NeoplasmsMeasurementMeasuresMedicalMethodsMonitorNoiseOutcomePhasePopulationPopulations at RiskProceduresProcessProtocols documentationPublic HealthPublic Health SchoolsReadinessReference StandardsReproducibilityResolutionRiskSamplingSignal TransductionSiteSmall Business Innovation Research GrantSourceSystemSystems AnalysisTechniquesTechnologyTestingTimeToxic effectTrainingUrineValidationWorkcomputerized data processingcostdesigndisorder preventiondrinking waterexperienceexposed human populationimprovedinstrumentmeetingsmonomethylarsonic acidnoveloxidationprofessorprogramsprototypepublic health relevanceresponsesensortoolurinaryusability
项目摘要
DESCRIPTION (provided by applicant): Giner, Inc. proposes a portable, inexpensive, and rapid-response monitor for arsenic speciation in urine. Arsenic species excreted in urine are reflective of exposure to toxic arsenic species, and therefore this monitor will be a valuable tool
in medical diagnostics and epidemiological studies by allowing determination of arsenic exposure by a technique that is faster and less expensive than traditional methods. Improved capability of monitoring exposure will have positive public health outcomes, as long- term exposure to arsenic is associated with health problems including cancer and cardiovascular disease. The phase I program developed a sensor capable of electrochemical detection of arsenic (III), total inorganic arsenic, and dimethylarsenic acid. Total organic arsenic was determined through a sample treatment process followed by electrochemical detection. The phase II program will include further optimization of all methods and processes, design of a prototype device, and validation of the device with real urine samples from epidemiological studies. The phase II program will result in a practical, robust, and accurate arsenic speciation device.
描述(由申请人提供):Giner,Inc.提出了一种便携式、廉价和快速反应的尿砷形态监测仪。尿中排出的砷物种反映了接触有毒砷物种的情况,因此这项监测将是一个有价值的工具。
在医学诊断和流行病学研究中,通过使用一种比传统方法更快、更便宜的技术来确定砷暴露。提高监测暴露的能力将产生积极的公共健康结果,因为长期暴露在砷中与包括癌症和心血管疾病在内的健康问题有关。第一阶段计划开发了一种能够电化学检测砷(III)、总无机砷和二甲基砷酸的传感器。总有机砷的测定通过样品处理过程,然后进行电化学检测。第二阶段计划将包括进一步优化所有方法和流程,设计一个原型设备,并用流行病学研究中的真实尿样对该设备进行验证。第二阶段计划将产生一个实用、坚固和准确的砷形态分析装置。
项目成果
期刊论文数量(0)
专著数量(0)
科研奖励数量(0)
会议论文数量(0)
专利数量(0)
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{{ truncateString('BADAWI M DWEIK', 18)}}的其他基金
Powered Knee Prosthesis Incorporating Battery-Capacitor Hybrid
采用电池-电容器混合动力的动力膝关节假体
- 批准号:
8394423 - 财政年份:2012
- 资助金额:
$ 51.05万 - 项目类别:
Rapid and On-site Monitoring of Urinary Arsenic Metabolites
尿砷代谢物的快速现场监测
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8879144 - 财政年份:2012
- 资助金额:
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8196685 - 财政年份:2012
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$ 51.05万 - 项目类别:
Rapid and On-site Monitoring of Urinary Arsenic Metabolites
尿砷代谢物的快速现场监测
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8432610 - 财政年份:2012
- 资助金额:
$ 51.05万 - 项目类别:
High-Voltage Compact Capacitor for Implantable Defibrillator
用于植入式除颤器的高压紧凑型电容器
- 批准号:
7925557 - 财政年份:2008
- 资助金额:
$ 51.05万 - 项目类别:
High-Voltage Compact Capacitor for Implantable Defibrillator
用于植入式除颤器的高压紧凑型电容器
- 批准号:
7480846 - 财政年份:2008
- 资助金额:
$ 51.05万 - 项目类别:
Field-Deployable Monitor to Assess Personal Exposure to Multiple Heavy Metals
可现场部署的监测器,用于评估个人对多种重金属的暴露情况
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- 批准号:
7363878 - 财政年份:2007
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$ 51.05万 - 项目类别:
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6550646 - 财政年份:2001
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$ 51.05万 - 项目类别:
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用于植入式除颤器的小型化电容器
- 批准号:
6298667 - 财政年份:2001
- 资助金额:
$ 51.05万 - 项目类别:
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