Cancer Prevention Training in Nutrition, Exercise & Genetics

描述(由申请人提供)：癌症预防领域的跨学科性质需要广泛的研究技能。在过去的9年里，我们成功地实施了癌症教育和职业发展计划(CECDP)，该计划提供跨学科的培训，重点是人类营养、运动、遗传学和相关代谢途径在癌症易感性和预防方面的相互关系。这一培训计划的目标是：1.继续开发和实施新的课程和相关的新课程，为流行病学、营养学和人类生物学(包括遗传学、分子/细胞生物学和医学)三个领域的博士后和博士后研究员提供二级领域的跨学科培训。博士学位在一个领域的学员完成这些领域中另一个领域的课程。2.在进行跨学科癌症预防研究方面提供丰富的研究经验，重点是人类营养、遗传学和相关的代谢途径。我们建议培训4名博士后研究员和3名博士后研究员。正式的课程和学位将由华盛顿大学的三个参与项目授予：流行病学、营养学和公共卫生遗传学。每个受训人员都将完成CECDP在其博士领域以外的中学领域开发的新课程。课程以现有的UW课程为基础，外加由CECDP开发或共同赞助的5门课程，以填补跨学科培训的空白。本课程经过了广泛的修订和加强，以反映癌症生物学知识的不断增加，遗传和生物标记物分析技术的快速变化，以及将人类遗传学的最新进展放在更广泛的公共卫生背景下的需要。受训人员将在弗雷德·哈钦森癌症研究中心的三个部门获得癌症预防研究的经验：癌症预防、流行病学和人类生物学。学员可以接触到这些单位的大量研究资源，以及优秀的教师导师。每个研究员将至少有两名来自不同学科的研究导师。由参与计划的领导人组成的咨询委员会将挑选受训人员，监督他们的进展，并向计划主任提供建议。完成这项计划的学员具有教学和研究经验，使他们能够成为多学科癌症预防研究项目的知识渊博的调查人员。

DESCRIPTION (provided by applicant): The interdisciplinary nature of the field of cancer prevention requires a broad spectrum of research skills. In the past 9 years, we have successfully conducted a Cancer Education and Career Development Program (CECDP), which provides interdisciplinary training with emphasis on the interrelationships of human nutrition, exercise, genetics and related metabolic pathways in cancer susceptibility and prevention. The objectives of this training program are: 1. To continue to develop and implement a new curriculum and associated new courses to provide interdisciplinary training in a secondary area to pre- and post-doctoral fellows in three fields: Epidemiology, Nutrition, and Human Biology (including Genetics, Molecular/Cellular Biology and Medicine). Trainees whose doctorate is in one area complete the curriculum in another of these areas. 2. To provide extensive research experience in the conduct of transdisciplinary cancer prevention research, with emphasis on human nutrition, genetics and associated metabolic pathways. We propose to train 4 pre- and 3 post-doctoral fellows. Formal coursework and degrees will be given by three participating programs of the University of Washington: Epidemiology, Nutritional Sciences, and Public Health Genetics. Each trainee will complete a new curriculum developed by this CECDP in a secondary area outside the field of his/her PhD. The curriculum is based on current UW courses, plus 5 courses developed by or co-sponsored by this CECDP to fill gaps in interdisciplinary training. This curriculum has been extensively revised and enhanced to reflect the increasing knowledge of cancer biology, the rapidly changing technologies for genetic and biomarker assays, and the need to place the most recent advances in human genetics in the broader public health context. Trainees will gain experience in cancer prevention research within three units of the Fred Hutchinson Cancer Research Center: Cancer Prevention, Epidemiology, and Human Biology. Trainees have access to the considerable research resources of these units, as well as to the outstanding faculty mentors. Each fellow will have at least two research mentors from different disciplines. An Advisory Committee composed of leaders of the participating programs will select trainees, monitor their progress and advise the Program Director. Trainees who complete this program have the didactic and research experience to allow them to be knowledgeable investigators on multidisciplinary cancer prevention research projects.