Investigating the utility of therapeutic drug monitoring of beta-lactam antibiotics in hospitalised patients

研究β-内酰胺类抗生素治疗药物监测在住院患者中的效用

• 批准号: nhmrc : 569917
• 负责人: Prof Jason Roberts
• 金额: $ 14.4万
• 依托单位: The University of Queensland
• 依托单位国家: 澳大利亚
• 项目类别: Early Career Fellowships
• 财政年份: 2009
• 资助国家: 澳大利亚
• 起止时间: 2009-01-01 至 2013-12-31
• 项目状态: 已结题
• 来源: https://researchdata.edu.au/investigating-utility-therapeutic-hospitalised-patients/116141
• 关键词: Investigating; utility; therapeutic; drug; monitoring

The appropriate dosing of antibiotics for patients admitted to hospital is based on broad guidelines derived from studies in healthy volunteers or in patients that may have different types of infections. Minor changes in the clinical state of the patients can require significant dosing adjustments. The best way to guarantee appropriate antibiotic therapy is to individualize doses based on blood concentration data. We aim to determine the utility of dose adjustment in hospitalized patients.

住院患者的适当抗生素剂量是基于对健康志愿者或可能患有不同类型感染的患者进行的研究得出的广泛指南。患者临床状态的微小变化可能需要显著的剂量调整。确保适当抗生素治疗的最佳方法是根据血药浓度数据制定个体化剂量。我们的目的是确定住院患者剂量调整的效用。