Robust antibiotic dosing for critically ill patients receiving renal replacement therapy

重症监护患者往往会出现肾衰竭，需要透析。不幸的是，几乎没有信息可以告知临床医生这些患者的抗生素适当剂量，使他们因治疗无效而死亡的风险增加。我们的项目旨在为全球使用的多种类型的透析制定剂量指南，以实现血液中的浓度，从而优化这些重症患者的抗生素效果。

Intensive Care patients more often than not, develop kidney failure requiring dialysis. Unfortunately there is little information available to inform clinicians of appropriate doses for antibiotics in these patients, putting them at an increased risk of death from ineffective treatment. Our project aims to develop dosing guidelines for the many types of dialysis used globally to achieve concentrations in the blood that optimise antibiotic effects in these most critically ill patients.