Antibiotic optimisation for severely ill patients

重症患者的抗生素优化

• 批准号: nhmrc : 1048652
• 负责人: Prof Jason Roberts
• 金额: $ 19.44万
• 依托单位: The University of Queensland
• 依托单位国家: 澳大利亚
• 项目类别: Career Development Fellowships
• 财政年份: 2013
• 资助国家: 澳大利亚
• 起止时间: 2013-01-01 至 2017-12-31
• 项目状态: 已结题
• 来源: https://researchdata.edu.au/antibiotic-optimisation-severely-ill-patients/112027
• 关键词: Antibiotic; optimisation; severely; ill; patients

Ineffective antibiotic therapy is associated with increased mortality in infected patients in the intensive care unit (ICU). Early administration of efficacious antibiotic therapy improves survival substantially. This work seeks to extend upon my previous studies that have described the different concentrations of antibiotics between ICU patients and non-ICU patients. Predicting when to change antibiotic doses in ICU patients is likely to substantially improve patient outcomes.

无效的抗生素治疗与重症监护病房 (ICU) 感染患者的死亡率增加有关。及早给予有效的抗生素治疗可显着提高生存率。这项工作旨在扩展我之前的研究，这些研究描述了 ICU 患者和非 ICU 患者之间抗生素浓度的不同。预测何时改变 ICU 患者的抗生素剂量可能会大大改善患者的预后。