Adolescent Cancer Survivors & Parents: Worries & Challenges at End-of-Treatment

青少年癌症幸存者

• 批准号: 8619872
• 负责人: Amy J Walker
• 金额: $ 7.87万
• 依托单位: UNIVERSITY OF WASHINGTON
• 依托单位国家: 美国
• 财政年份: 2014
• 资助国家: 美国
• 起止时间: 2014-09-28 至 2016-07-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/8619872
• 关键词: Acute Lymphocytic Leukemia; Address; Adolescent; Aftercare; Age; Anxiety; B-Cell NonHodgkins Lymphoma; Behavior; Behavioral; Cancer Survivor; Caring; Child; Chronic Disease; Code; Comprehensive Cancer Center; Data; Databases; Development; Diagnosis; Effectiveness; Emotional; Extramural Activities; Face; Grant; Health; Health Personnel; Healthcare Systems; Hodgkin Disease; Infection; Injury; Intervention; Interview; Late Effects; Lead; Life; Life Style; Long-Term Survivors; Malignant Neoplasms; Measures; Morbidity - disease rate; Non-Hodgkin' s Lymphoma; Outcome; Pacific Northwest; Parents; Participant; Phase; Pilot Projects; Program Development; Protocols documentation; Questionnaires; Recruitment Activity; Risk; Role; Services; Social Environment; Solid Neoplasm; Structure; Subgroup; Survivors; Telephone Interviews; Time; base; cancer therapy; design; empowered; expectation; experience; follow-up; high risk; improved; mortality; peer; psychosocial; public health relevance; survivorship; therapy development; treatment effect; treatment program

Project summary/abstract Approximately 5,000 adolescents ages 14 to 18 years will be diagnosed with cancer each year in the US and an estimated 80% will become long-term survivors. Adolescent cancer long-term survivors have some of the highest risks for treatment-related late effects, predisposing them to cancer-related morbidity and early mortality, as well as negative psychosocial and developmental outcomes. A particularly challenging time for adolescent survivors and their parents is end-of-treatment. End-of-treatment means the adolescent is no longer receiving treatment, and interactions with health care providers become much fewer and less frequent for adolescents and parents. End-of treatment presents intense challenges for adolescents and their parents, but a paucity of studies have described adolescent or parent's experiences at this juncture. The specific aims of this pilot study are to: 1) Describe and compare the worries, perceived challenges, and ways of managing these issues for adolescent cancer survivors (14 to 18 years) and their parents at end-of-treatment and follow- up; 2) Describe the behavioral-emotional functioning of adolescents and parents' anxiety at end-of-treatment and follow-up; and 3) Evaluate the effectiveness of the study's protocol for recruitment of adolescent-parent dyads. Forty participants (20 adolescents, 20 parents) will be recruited from a Comprehensive Cancer Center in the Pacific Northwest. Two subgroups will be recruited: 1) adolescents with acute lymphoblastic leukemia and non-Hodgkin's B-cell lymphoma and their parents and 2) adolescents with solid tumors, Hodgkin's disease, and other non-Hodgkin lymphomas and their parents. Semi-structured telephone interviews will be conducted separately for adolescents and parents within one month of the end-of-treatment and at three and six months. Content analysis with inductive coding will be used to analyze the interview data. Standardized questionnaires will be used to measure adolescents' emotional-behavioral functioning and parental anxiety. Study findings will inform the eventual development of a larger extramural grant and an adolescent-parent intervention to improve end-of-treatment transition. This study will be the first important step in addressing the health and developmental needs of adolescent cancer survivors and their parents after treatment.

项目总结/文摘