Adolescent Cancer Survivors & Parents: Worries & Challenges at End-of-Treatment

产品说明：在美国，每年约有5,000名14至18岁的青少年被诊断患有癌症，估计80%将成为长期幸存者。青少年癌症长期幸存者有一些最高的风险与治疗有关的晚期效应，使他们容易患上癌症相关的疾病和早期死亡，以及负面的心理和发展结果。对于青少年幸存者及其父母来说，一个特别具有挑战性的时刻是治疗结束。治疗结束意味着青少年不再接受治疗，青少年和父母与卫生保健提供者的互动变得越来越少。治疗结束对青少年及其父母提出了严峻的挑战，但很少有研究描述了青少年或父母在这一时刻的经历。本试验研究的具体目的是：1）描述和比较青少年癌症幸存者的担忧，感知的挑战和管理这些问题的方法（14至18岁）及其父母在治疗结束和随访时的行为-情绪功能; 2）描述青少年的行为-情绪功能和父母在治疗结束和随访时的焦虑;和3）评估本研究方案招募亲-亲二联体的有效性。将从太平洋西北部的综合癌症中心招募40名参与者（20名青少年，20名父母）。将招募两个亚组：1）患有急性淋巴细胞白血病和非霍奇金B细胞淋巴瘤的青少年及其父母，2）患有实体瘤、霍奇金病和其他非霍奇金淋巴瘤的青少年及其父母。将在治疗结束后一个月内以及三个月和六个月分别对青少年和家长进行半结构化电话访谈。内容分析与归纳编码将用于分析访谈数据。标准化问卷将被用来测量青少年的情绪行为功能和父母的焦虑。研究结果将为最终制定更大的校外补助金和家长干预措施提供信息，以改善治疗结束后的过渡。这项研究将是解决青少年癌症幸存者及其父母治疗后的健康和发展需求的第一个重要步骤。

DESCRIPTION: Approximately 5,000 adolescents, ages 14 to 18 years, will be diagnosed with cancer each year in the US and an estimated 80% will become long-term survivors. Adolescent cancer long-term survivors have some of the highest risks for treatment-related late effects, predisposing them to cancer-related morbidity and early mortality, as well as negative psychosocial and developmental outcomes. A particularly challenging time for adolescent survivors and their parents is end-of-treatment. End-of-treatment means the adolescent is no longer receiving treatment, and interactions with health care providers become much fewer and less frequent for adolescents and parents. End-of treatment presents intense challenges for adolescents and their parents, but a paucity of studies have described adolescent or parent's experiences at this juncture. The specific aims of this pilot study are to: 1) Describe and compare the worries, perceived challenges, and ways of managing these issues for adolescent cancer survivors (14 to 18 years) and their parents at end-of-treatment and follow- up; 2) Describe the behavioral-emotional functioning of adolescents and parents' anxiety at end-of-treatment and follow-up; and 3) Evaluate the effectiveness of the study's protocol for recruitment of adolescent-parent dyads. Forty participants (20 adolescents, 20 parents) will be recruited from a Comprehensive Cancer Center in the Pacific Northwest. Two subgroups will be recruited: 1) adolescents with acute lymphoblastic leukemia and non-Hodgkin's B-cell lymphoma and their parents and 2) adolescents with solid tumors, Hodgkin's disease, and other non-Hodgkin lymphomas and their parents. Semi-structured telephone interviews will be conducted separately for adolescents and parents within one month of the end-of-treatment and at three and six months. Content analysis with inductive coding will be used to analyze the interview data. Standardized questionnaires will be used to measure adolescents' emotional-behavioral functioning and parental anxiety. Study findings will inform the eventual development of a larger extramural grant and an adolescent-parent intervention to improve end-of-treatment transition. This study will be the first important step in addressing the health and developmental needs of adolescent cancer survivors and their parents after treatment.