动物-猫眼课题宝

动物

批准号：

8722008

负责人：

Thomas Heppner

金额：

$37.67万

依托单位：

UNIVERSITY OF VERMONT & ST AGRIC COLLEGE

依托单位国家：

美国

项目类别：

财政年份：

资助国家：

美国

项目状态：

已结题

起止时间：

至 2016-07-31

来源：

https://reporter.nih.gov/project-details/8722008

关键词：

Actins Age Animal Experiments Animals Astrocytes Biosensor Boxing Breeding Calcium Signaling Caliber Caring Cerebrovascular Circulation Clip Communication Communities Contracts Databases Date of birth Diet Disease Doxycycline Ear Endothelial Cells Endothelium Ensure Equipment Food Gel Gender Genetic Genotype Glial Fibrillary Acidic Protein Goals Health Heterozygote Individual Laboratories Location Mails Methods Monitor Mouse Strains Mus Online Systems Operative Surgical Procedures Population Power Sources Progress Reports Rattus Regulation Research Research Personnel Research Project Grants Schedule Scheme Security Services Signal Transduction Smooth Muscle Smooth Muscle Myocytes Specific qualifier value System Tail Tetracyclines Time Tissues Transgenic Mice Transgenic Organisms Universities Vermont Water Weaning Work animal care base cerebrovascular drinking water feeding instrumentation meetings mouse development mouse model novel offspring overexpression programs promoter ratiometric sex success

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中文摘要

翻译

该计划项目的总体目标是了解在正常和疾病状态下调节脑血管的机制。构成本PPG的所有四个项目都集中在这一目标上，每个项目都认识到实验的成功取决于从安乐死动物中正确分离组织、仔细实施外科手术和适当的术后护理。动物和仪器核心的首要任务是。提高每个研究者的研究项目的成功率。这包括提供处理动物种群的中心手段，确保手术使用的适当条件，并保持良好的动物术后护理。通过集中这些任务，这是共同的所有项目，动物和仪器核心允许研究人员专注于实验问题和管理独特的每个项目，以提高实验的成功。

英文摘要

The overall goal of the Program Project is to understand mechanisms regulating the cerebral vasculature in normal and disease states. All four projects that constitute this PPG are focused on this goal, and each recognizes that experimental success depends on the proper isolation of tissue from euthanized animals, careful implementation of surgical procedures and appropriate post-op care. The top priority of the Animal & Instrumentation Core is. to enhance the success of research projects for each investigator. This includes providing a central means for handling animal populations, ensuring proper conditions for surgical use, and maintaining excellent post-op care of animals. By centralizing these tasks, which are common to all projects, the Animal & Instrumentation Core allows investigators to focus on experimental issues and management unique to each project to enhance experimental success.

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