Multidisciplinary Training in Environmental Toxicology

参见说明）： MSU的多学科环境和综合毒理学科学（EITS）培训计划 培养具有环境毒理学基础知识和研究专长的科学家 在生物医学基础科学研究生课程中获得。博士前学员必须满足完整的博士学位 他们的“家”生物医学博士课程的要求，并完成课程，研究和 通过综合毒理学中心管理的EITS博士课程的互动方面 （CIT）。培训的双重性质是公认的生物医学科学-环境毒理学标题 授予的学位（例如，生物化学和分子生物学-环境毒理学博士）。 该计划的毕业生有能力进行研究，并与其他科学家互动， 解决复杂的环境毒理学问题，需要协作，多学科的过程 方法。 20名培训教师在7个基础科学博士课程中进行博士前培训 （药理学/毒理学，遗传学，生物化学和分子生物学，食品科学，细胞和 分子生物学、比较医学与综合生物学、微生物学与分子遗传学）。 除了基本的生物医学科学教育和环境毒理学研究培训外， 教学性、毒理学导向的课程以及EITS计划的其他要求。这门课程和 CIT提供的不太正式的多学科互动和活动， 知识比仅在基础科学项目中可获得的知识要多。学员的研究课题跨越各种 器官系统，包括基因-环境相互作用和环境因素的作用， 疾病易感性和进展。有一个综合生物学的重点，以研究培训， 它强调整个动物，细胞为基础的，分子和基因组的方法来了解 在合作的气氛中的毒性机制。博士后培养计划不仅涉及 在培训学院的实验室进行研究，但也获得额外的环境 毒理学经验和职业建设培训，通过参与CIT和大学范围内的活动。 该申请是为了支持六名博士前和三名博士后培训生，从而继续高度 有效的多学科和互动的培训计划，结合正式和非正式的方法， 为毕业生在环境毒理学领域的研究中担任领导角色做好准备。 相关性（参见说明）： 暴露于环境中的各种物质可直接导致疾病或加重由以下物质引起的疾病： 其他因素减少此类接触对人类健康的影响，并制定有效的干预措施 要求公共卫生官员和科学家在几个领域接受过培训， 并了解化学制剂引起或加重疾病的机制。该方案采用 一个优秀的，研究密集型的教师在合作环境中的博士培训经验， 培训科学家解决环境问题的毒理学机制。

See instructions): The multidisciplinary Environmental and Integrative Toxicological Sciences (EITS) Training Program at MSU produces scientists having a base knowledge in environmental toxicology coupled with research expertise gained in a biomedical basic science graduate program. Predoctoral trainees must meet the full PhD requirements of their "home" biomedical doctoral program and complete the coursework, research and interactive aspects of the EITS Doctoral Program administered through the Center for Integrative Toxicology (CIT). The dual nature of the training is recognized in the biomedical science-environmental toxicology title of the degree awarded (e.g., PhD in "Biochemistry and Molecular Biology-Environmental Toxicology"). Graduates of the program are well equipped to conduct research and interact with other scientists in the course of solving complex environmental toxicological problems that require collaborative, multidisciplinary approaches. Twenty training faculty conduct predoctoral training in seven basic science PhD programs (Pharmacology/Toxicology, Genetics, Biochemistry and Molecular Biology, Food Science, Cell and Molecular Biology, Comparative Medicine and Integrative Biology, Microbiology and Molecular Genetics). Added to the basic biomedical science-based education and environmental toxicology research training are didactic, toxicology-oriented courses and other requirements of the EITS Program. This coursework and less formal multidisciplinary interactions and activities provided by the CIT impart a wider scope of knowledge than is available within basic science programs alone. Research topics for trainees span various organ systems and encompass gene-environment interactions and the role of environmental factors in disease susceptibility and progression. There is an integrative biology emphasis to the research training, which emphasizes whole animal, cell-based, molecular and genomic methodologies to understand mechanisms of toxicity in a collaborative atmosphere. The postdoctoral training program involves not only conducting research in the laboratories of the training faculty but also gaining additional environmental toxicology experience and career-building training through participation in CIT and University-wide activities. This application is for support of six predoctoral and three postdoctoral trainees, thereby continuing a highly effective multidisciplinary and interactive training program that combines formal and informal approaches to prepare graduates for leadership roles in research in the field of environmentaltoxicology. RELEVANCE (See instructions): ' Exposure to various agents in the environment can cause illness directly or exacerbate disease caused by other factors. Reducing the impact of such exposures on human health and devising effective interventions requires public health officials and scientists trained in several areas, including scientists equipped to study and understand mechanisms by which chemical agents cause or exacerbate illness. This program employs an excellent, research-intensive faculty experienced in doctoral training in a collaborative environment to train scientists to address toxicologic mechanisms of environmental concern.