Multidisciplinary Training in Environmental Toxicology

环境毒理学多学科培训

• 批准号: 9307838
• 负责人: JOHN J LAPRES
• 金额: $ 41.7万
• 依托单位: MICHIGAN STATE UNIVERSITY
• 依托单位国家: 美国
• 财政年份: 1989
• 资助国家: 美国
• 起止时间: 1989-07-01 至 2019-06-30
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/9307838
• 关键词: Training; environmental toxicology; multidisciplinary

DESCRIPTION (provided by applicant) The multidisciplinary Environmental and Integrative Toxicological Sciences (EITS) Training Program at MSU produces scientists having a base knowledge in environmental toxicology coupled with research expertise gained in a biomedical basic science graduate program. Pre-doctoral trainees must meet the full Ph.D. requirements of their partnering biomedical doctoral program and complete the coursework, research and interactive aspects of the EITS Doctoral Program administered through the Center for Integrative Toxicology (CIT). The dual nature of the training is recognized in the biomedical science-environmental toxicology title of the degree awarded (e.g., Ph.D. in "Biochemistry and Molecular Biology-Environmental Toxicology"). Graduates of the program are well equipped to conduct research and interact with other scientists in the course of solving complex environmental toxicological problems that require collaborative, multidisciplinary approaches. Twenty-three training faculty members conduct pre-doctoral training in eight basic science Ph.D. programs (Pharmacology/Toxicology, Genetics, Biochemistry and Molecular Biology, Food Science, Cell and Molecular Biology, Comparative Medicine and Integrative Biology, Microbiology and Molecular Genetics, Neuroscience). Added to the basic biomedical science-based education and environmental toxicology research training are didactic, toxicology-oriented courses and other requirements of the EITS Program. This coursework and less formal multidisciplinary interactions and activities provided by the CIT impart a wider scope of knowledge than is available within basic science programs alone. Research topics for trainees span various organ systems and encompass gene-environment interactions and the role of environmental factors in disease susceptibility and progression. There is an integrative biology emphasis to the research training, which emphasizes whole animal, cell-based, molecular and genomic methodologies to understand mechanisms of toxicity in a collaborative atmosphere. The postdoctoral training program involves not only conducting research in the laboratories of the training faculty but also gaining additional environmental toxicology experience and career- building training by following an individual development plan (IDP) and through participation in CIT and University-wide activities. This application is for support of seven pre-doctoral and two postdoctoral trainees, thereby continuing a highly effective multidisciplinary and interactive training program that combines formal and informal approaches to prepare graduates for leadership roles in research in the field of environmental toxicology.

描述(由申请人提供) 密歇根州立大学的多学科环境与综合毒理学(EITS)培训计划培养出具有环境毒理学基础知识的科学家，以及在生物医学基础科学研究生课程中获得的研究专业知识。博士前实习生必须满足其合作生物医学博士项目的全部博士要求，并完成由综合毒理学中心(CIT)管理的EITS博士项目的课程作业、研究和互动方面的工作。所授予学位的生物医学科学-环境毒理学头衔(例如，“生物化学和分子生物学-环境毒理学博士”)承认了培训的两面性。该项目的毕业生能够在解决复杂的环境毒理学问题的过程中进行研究并与其他科学家互动，这些问题需要合作、多学科的方法。23名培训教师在8个基础科学博士课程(药理学/毒理学、遗传学、生物化学和分子生物学、食品科学、细胞和分子生物学、比较医学和综合生物学、微生物学和分子遗传学、神经科学)进行博士前培训。除了以生物医学为基础的教育和环境毒理学研究培训外，EITS计划还要求提供以教学、毒理学为导向的课程和其他要求。这门课程和CIT提供的非正式的多学科互动和活动提供了比仅在基础科学项目中可获得的更广泛的知识范围。受训者的研究主题跨越各种器官系统，包括基因与环境的相互作用以及环境因素在疾病易感性和进展中的作用。研究培训强调综合生物学，强调整体动物、基于细胞的、分子和基因组方法，以了解合作气氛中的毒性机制。博士后培训计划不仅包括在培训教师的实验室进行研究，还包括通过遵循个人发展计划(IDP)并通过参与CIT和大学范围的活动来获得额外的环境毒理学经验和职业发展培训。这项申请是为了支持7名博士后和2名博士后实习生，从而继续一个高效的多学科和互动培训计划，将正式和非正式的方法结合起来，为毕业生在环境毒理学领域的研究担任领导角色做好准备。