Traumatic Brain Injury Across the Lifespan in Uganda Research Initiative
乌干达生命周期中的创伤性脑损伤研究计划
基本信息
- 批准号:8991969
- 负责人:
- 金额:$ 19.64万
- 依托单位:
- 依托单位国家:美国
- 项目类别:
- 财政年份:2015
- 资助国家:美国
- 起止时间:2015-07-01 至 2017-06-30
- 项目状态:已结题
- 来源:
- 关键词:AddressAfricaAfrica South of the SaharaBrain DiseasesCause of DeathClinicalCollaborationsCommon Data ElementConsultationsCountryDataData AnalysesData CollectionData ElementDevelopmentEconomic BurdenEducational CurriculumEducational process of instructingEducational workshopEpidemiologyEvaluationFactor AnalysisFacultyFutureGenerationsGoalsHealthHealth PolicyHospital ReferralsHospitalsHuman ResourcesIncidenceIncomeInformation SystemsInformation TechnologyInjuryInstitutionInternetInterventionIntervention StudiesJointsKnowledgeLiteratureLongevityMeasuresMentorsModelingNational Institute of Neurological Disorders and StrokeNatureNeurosurgeonOutcomePatientsPeer ReviewPopulationPreventionPreventivePublic HealthPublic Health SchoolsPublic SectorRecording of previous eventsRegistriesResearchResearch PersonnelResearch Project GrantsResearch ProposalsResourcesRiskRisk FactorsRunningSeasonal VariationsSecureSeveritiesSurgeonSystemTestingTrainingTraumaTraumatic Brain InjuryUgandaUnited States National Institutes of HealthUniversitiesViolenceVulnerable PopulationsWorkWorld Health Organizationbaseburden of illnessclinical caredata registrydesigndisabilityexperiencehealth economicsimprovedinjury burdeninnovationmortalityprogramsprospectivepublic health relevancerat Ran 2 proteinresponseskillssystematic review
项目摘要
DESCRIPTION (provided by applicant): Each year, it is estimated that more than 10 million people in the world suffer Traumatic Brain Injury (TBI), and in sub-Saharan Africa TBI rates are much higher than global averages. Rates of TBI mortality and disability in Uganda are similar to those throughout SSA, yet national data on the burden of injury are scarce. The large and growing burden of TBI in Uganda urgently requires a response, which in turn will require that critical knowledge gaps be addressed. We propose the Traumatic Brain Injury Across the Lifespan in Uganda (TBI-Uganda) Program to define the health and economic burden of traumatic brain injuries across the lifespan in Uganda in a collaborative research effort that will
define the burden of TBI, develop sustainable data systems, and train Ugandans in TBI research to help find and fill these gaps and advance a research-based response. Our innovative model of sustainable research collaboration will involve the Johns Hopkins University Bloomberg School of Public Health (JHU), USA and Makerere University School of Public Health (MU) and Mulago National Referral Hospital (MH) in Uganda. We will use US expertise to strengthen the Ugandan institutions, promote a sustainable research enterprise focused on TBI, and enable further use of research evidence by proposing a larger intervention study in Uganda. The project's research will identify gaps in public health expertise and in clinical care o TBI patients. We will apply these results to reduce the growing burden of TBI across the lifespan and propose a larger intervention study by the end of two years. We will first define core variables and Internet platforms for a data registry focused on traumatic brain injuries in Uganda (Specific Aim 1, months 1-6). We will then pilot-test the Internet-based the Kampala internet-Traumatic Brain Injury Registry (KiTBIR) registry at MH for 1 year (Specific Aim 2, months 7-18). This not only will improve understanding of TBI in Kampala, but also will test the viability of ongoing data systems and human resources support for such a secure internet-based registry, because continuous data collection system will be crucial to the design and evaluation of future interventions. Throughout the project we will develop research skills and data analysis capacity among a core group of TBI clinicians at MH and MU (Specific Aim 3, months 1-24), through researcher and stakeholder workshops as well as online courses in relevant health and policy topics. Finally, we will develop a research plan for an intervention study on TBI in Kampala as a joint JHU-MU proposal (R01) for research to evaluate a set of interventions using the KiTBIR (Specific Aim 4, months 20-24). Implementation of a TBI registry at MH will help clearly define the burden of TBI in Uganda and the risk factors associated with TBI incidence and outcome, and help identify correctable factors in the treatment of this population. The Internet-based approach to TBI registry development outlined in this proposal represents a significant advancement in data collection for TBI patients in the developing world.
描述(由申请人提供):据估计,每年世界上有超过1000万人遭受创伤性脑损伤(TBI),撒哈拉以南非洲的TBI率远远高于全球平均水平。乌干达的创伤性脑损伤死亡率和残疾率与整个撒哈拉以南非洲相似,但有关伤害负担的国家数据却很少。乌干达创伤性脑损伤的巨大和不断增长的负担迫切需要应对,这反过来又需要解决关键的知识差距。我们提出了乌干达终生创伤性脑损伤(TBI-Uganda)计划,以确定乌干达终生创伤性脑损伤的健康和经济负担,这是一项合作研究工作,
确定创伤性脑损伤的负担,开发可持续的数据系统,并在创伤性脑损伤研究方面培训乌干达人,以帮助发现和填补这些空白,并推进基于研究的应对措施。我们创新的可持续研究合作模式将涉及美国约翰霍普金斯大学彭博公共卫生学院(JHU)和乌干达马凯雷雷大学公共卫生学院(MU)和穆拉戈国家转诊医院(MH)。我们将利用美国的专业知识来加强乌干达的机构,促进以TBI为重点的可持续研究企业,并通过在乌干达进行更大规模的干预研究来进一步利用研究证据。该项目的研究将确定公共卫生专业知识和创伤性脑损伤患者临床护理方面的差距。我们将应用这些结果来减少TBI在整个生命周期中不断增长的负担,并在两年后提出一项更大规模的干预研究。我们将首先定义核心变量和互联网平台的数据注册集中在创伤性脑损伤在乌干达(具体目标1,月1-6)。然后,我们将在MH对基于互联网的坎帕拉互联网创伤性脑损伤登记处(KiTBIR)进行为期1年的试点测试(具体目标2,第7-18个月)。这不仅将增进对坎帕拉创伤性脑损伤的了解,而且还将检验现有数据系统和人力资源支持对这一安全的互联网登记册的可行性,因为持续的数据收集系统对于设计和评价今后的干预措施至关重要。在整个项目中,我们将通过研究人员和利益相关者研讨会以及相关健康和政策主题的在线课程,在MH和MU的TBI临床医生核心小组中开发研究技能和数据分析能力(具体目标3,1-24个月)。最后,我们将为坎帕拉的TBI干预研究制定一项研究计划,作为JHU-MU联合提案(R 01),用于研究评估使用KiTBIR(具体目标4,20-24个月)的一系列干预措施。在MH实施TBI登记将有助于明确定义乌干达TBI的负担以及与TBI发病率和结局相关的风险因素,并有助于确定治疗该人群的可纠正因素。本提案中概述的基于互联网的TBI注册开发方法代表了发展中国家TBI患者数据收集的重大进步。
项目成果
期刊论文数量(0)
专著数量(0)
科研奖励数量(0)
会议论文数量(0)
专利数量(0)
数据更新时间:{{ journalArticles.updateTime }}
{{
item.title }}
{{ item.translation_title }}
- DOI:
{{ item.doi }} - 发表时间:
{{ item.publish_year }} - 期刊:
- 影响因子:{{ item.factor }}
- 作者:
{{ item.authors }} - 通讯作者:
{{ item.author }}
数据更新时间:{{ journalArticles.updateTime }}
{{ item.title }}
- 作者:
{{ item.author }}
数据更新时间:{{ monograph.updateTime }}
{{ item.title }}
- 作者:
{{ item.author }}
数据更新时间:{{ sciAawards.updateTime }}
{{ item.title }}
- 作者:
{{ item.author }}
数据更新时间:{{ conferencePapers.updateTime }}
{{ item.title }}
- 作者:
{{ item.author }}
数据更新时间:{{ patent.updateTime }}
ADNAN A HYDER其他文献
ADNAN A HYDER的其他文献
{{
item.title }}
{{ item.translation_title }}
- DOI:
{{ item.doi }} - 发表时间:
{{ item.publish_year }} - 期刊:
- 影响因子:{{ item.factor }}
- 作者:
{{ item.authors }} - 通讯作者:
{{ item.author }}
{{ truncateString('ADNAN A HYDER', 18)}}的其他基金
United States-Zambia Addressing Risk Factors for Non-Communicable Diseases (US-Zambia Risk NCD)
美国-赞比亚解决非传染性疾病的风险因素(美国-赞比亚风险非传染性疾病)
- 批准号:
10462351 - 财政年份:2022
- 资助金额:
$ 19.64万 - 项目类别:
United States-Zambia Addressing Risk Factors for Non-Communicable Diseases (US-Zambia Risk NCD)
美国-赞比亚解决非传染性疾病的风险因素(美国-赞比亚风险非传染性疾病)
- 批准号:
10594508 - 财政年份:2022
- 资助金额:
$ 19.64万 - 项目类别:
Trauma and Injury Research Training Program-Zambia
创伤和伤害研究培训计划-赞比亚
- 批准号:
10673877 - 财政年份:2021
- 资助金额:
$ 19.64万 - 项目类别:
Trauma and Injury Research Training Program-Zambia
创伤和伤害研究培训计划-赞比亚
- 批准号:
10490415 - 财政年份:2021
- 资助金额:
$ 19.64万 - 项目类别:
Traumatic Brain Injury Across the Lifespan in Zambia
赞比亚一生中的创伤性脑损伤
- 批准号:
10299692 - 财政年份:2021
- 资助金额:
$ 19.64万 - 项目类别:
Trauma and Injury Research Training Program-Zambia
创伤和伤害研究培训计划-赞比亚
- 批准号:
10393221 - 财政年份:2021
- 资助金额:
$ 19.64万 - 项目类别:
Strengthening Ethical Review Capacity in Democratic Republic of Congo (SERC-DRC)
加强刚果民主共和国的道德审查能力 (SERC-DRC)
- 批准号:
10321965 - 财政年份:2020
- 资助金额:
$ 19.64万 - 项目类别:
Fogarty African Bioethics Consortium Post-Doctoral Fellowship Program
福格蒂非洲生物伦理学联盟博士后奖学金计划
- 批准号:
10161879 - 财政年份:2017
- 资助金额:
$ 19.64万 - 项目类别:
Fogarty African Bioethics Consortium Post-Doctoral Fellowship Program
福格蒂非洲生物伦理学联盟博士后奖学金计划
- 批准号:
9921512 - 财政年份:2017
- 资助金额:
$ 19.64万 - 项目类别:
Improving the quality and efficiency of the Univ Zambia Research Ethics Committee with HIV Research Training
通过艾滋病毒研究培训提高赞比亚大学研究伦理委员会的质量和效率
- 批准号:
9118444 - 财政年份:2016
- 资助金额:
$ 19.64万 - 项目类别:
相似海外基金
Multi-component interventions to reducing unhealthy diets and physical inactivity among adolescents and youth in sub-Saharan Africa (Generation H)
采取多方干预措施减少撒哈拉以南非洲青少年的不健康饮食和缺乏身体活动(H 代)
- 批准号:
10106976 - 财政年份:2024
- 资助金额:
$ 19.64万 - 项目类别:
EU-Funded
Exploring the mental health and wellbeing of adolescent parent families affected by HIV in South Africa
探讨南非受艾滋病毒影响的青少年父母家庭的心理健康和福祉
- 批准号:
ES/Y00860X/1 - 财政年份:2024
- 资助金额:
$ 19.64万 - 项目类别:
Fellowship
Decolonization, Appropriation and the Materials of Literature in Africa and its Diaspora
非洲及其侨民的非殖民化、挪用和文学材料
- 批准号:
EP/Y024516/1 - 财政年份:2024
- 资助金额:
$ 19.64万 - 项目类别:
Research Grant
Exploring "Actionable Information" for Learning Improvement in Rural East Africa: A Positive Deviance Approach
探索东非农村地区学习改进的“可行信息”:积极偏差方法
- 批准号:
24K00390 - 财政年份:2024
- 资助金额:
$ 19.64万 - 项目类别:
Grant-in-Aid for Scientific Research (B)
ePowerCart - Affordable Mobile Clean Energy for Remote Communities in Rural Sub-Saharan Africa and India
ePowerCart - 为撒哈拉以南非洲和印度农村偏远社区提供经济实惠的移动清洁能源
- 批准号:
10076185 - 财政年份:2024
- 资助金额:
$ 19.64万 - 项目类别:
Collaborative R&D
Protecting Women from Economic shocks to fight HIV in Africa (POWER)
保护非洲妇女免受经济冲击,抗击艾滋病毒 (POWER)
- 批准号:
MR/Y003837/1 - 财政年份:2024
- 资助金额:
$ 19.64万 - 项目类别:
Fellowship
Tackling antimicrobial resistance across dentistry in Sub-Saharan Africa.
解决撒哈拉以南非洲牙科领域的抗菌素耐药性问题。
- 批准号:
MR/Y019695/1 - 财政年份:2024
- 资助金额:
$ 19.64万 - 项目类别:
Research Grant
Water stressed cities: individual choice, access to water and pathways to resilience in sub-Saharan Africa
缺水城市:撒哈拉以南非洲地区的个人选择、水资源获取和恢复力途径
- 批准号:
MR/X022943/1 - 财政年份:2024
- 资助金额:
$ 19.64万 - 项目类别:
Fellowship
The Open fracture National Evaluation (ONE) Study - South Africa: Improving outcomes in the care of open fractures in low resource settings
开放性骨折国家评估 (ONE) 研究 - 南非:改善资源匮乏地区开放性骨折的护理效果
- 批准号:
MR/Y00955X/1 - 财政年份:2024
- 资助金额:
$ 19.64万 - 项目类别:
Fellowship
Recognising & supporting informal mhealth in Africa through grassroots interventions (REIMAGINE)
认识
- 批准号:
MR/Y015614/1 - 财政年份:2024
- 资助金额:
$ 19.64万 - 项目类别:
Research Grant