Traumatic Brain Injury Across the Lifespan in Zambia

项目摘要/摘要 赞比亚创伤性脑损伤(TBI-赞比亚)项目的总体目标是 定义赞比亚人一生中创伤性脑损伤的健康和经济负担。我们会做的 这是通过使用创伤性脑损伤(Brain)电子登记处加强当地数据基础设施 卢萨卡伤害登记处(BRAIL)收集在大学教学医院看到的所有脑损伤的数据。我们的 该方法将涉及米尔肯研究所公共卫生学院、乔治大学 美国华盛顿大学、赞比亚大学公共卫生学院及其大学 赞比亚卢萨卡教学医院(UTH)。GW和UNZA共享一项有文件记录的研究承诺 培训、在伤害和保健服务研究中应用电子登记处方面的专门知识，以及 富有成效的协作工作的历史。UNZA和UTH共同致力于提供最高质量 为赞比亚的贫困社区提供服务，并专注于优化资源匮乏的成果 设置。我们的提案将利用在理解创伤和大脑的影响方面的共同利益 疾病和加强研究能力，解决在解决这些健康问题方面的两个关键差距 -创建关于全面发展援助的国家分类数据，确定其风险和弱势群体及其影响 潜在的干预措施，并培养一支具有研究和数据管理技能的核心临床医生队伍。我们的 TBI与赞比亚的合作将有助于加强UNZA/UTH和赞比亚内部的能力，以应用这些 将方法论推广到卫生保健的其他领域。这项提案的具体目标是：(1)界定核心 赞比亚创伤性脑损伤数据登记的变量和数字平台；(2)试点测试 赞比亚大学教学医院的数字创伤性脑损伤登记，为期一年；以及(3) 在大学教学中培养一支具有研究技能和数据分析能力的核心临床医生队伍 赞比亚大学医院。我们将应用这项研究的成果来减轻TBI日益增长的负担 并在两年内提出一项更大规模的干预研究。 我们将以颅脑损伤患者为重点，开发数字化登记，并将在外科 UTH急诊室(接收、评估所有创伤患者并开始治疗)。 关于脑损伤的流行病学信息、脑损伤的发生、性质、类型和结果，包括风险 因素分析和季节变化将通过12个月的前瞻性数据收集过程收集。 这些数据将对评估未来的干预措施和勾勒出政策建议至关重要。为了加强 为了应对创伤性脑损伤，我们将在临床医生(外科医生、创伤外科医生、 通过现场实践培训、短期讲习班和在线课程，在赞比亚开展了神经外科医生培训。

Project Summary/Abstract The overall goal of the Traumatic Brain Injury Across the Lifespan in Zambia (TBI-Zambia) program is to define the health and economic burden of traumatic brain injuries across the lifespan in Zambia. We will do this by strengthening the local data infrastructure with an electronic registry on traumatic brain injuries (Brain Injury Registry of Lusaka (BraiL)) to collect data on all TBI seen at the University Teaching Hospital. Our approach will involve close collaboration between Milken Institute School of Public Health, the George Washington University (GW), USA, the University of Zambia School of Public Health (UNZA) and its University Teaching Hospital (UTH), Lusaka, Zambia. GW and UNZA share a documented commitment to research training, expertise in application of electronic registries in injuries and health services research, as well as a history of productive collaborative work. UNZA and UTH share a commitment to providing the highest quality service to the under-privileged communities in Zambia, and focus on optimizing outcomes in low-resource settings. Our proposal will leverage the shared interest in understanding the impact of trauma and brain disorders and strengthening research capacity and tackle two critical gaps in addressing these health concerns – create national, disaggregated data on TBI, define their risks and vulnerable groups and the impact of potential interventions and develop a core group of clinicians with research and data management skills. Our TBI-Zambia collaboration will help strengthen capacity within UNZA/UTH and Zambia to apply these methodologies to other areas of health care. The specific aims of this proposal are: (1) To Define core variables and digital platforms for a data registry focused on traumatic brain injuries in Zambia; (2) To Pilot-test a digital traumatic brain injury registry at University Teaching Hospital, University of Zambia for a year; and (3) To Develop a core group of clinicians with research skills and data analysis capacity at University Teaching Hospital, University of Zambia. We will apply the results of the study to reduce the growing burden of TBI across the lifespan and propose a larger intervention study by the end of two years. With TBI patients as our focus, we will develop digital registry, which will be implemented in the Surgical Emergency Unit (where all trauma patients are received, assessed and treatment is initiated) of UTH. Information on the epidemiology of the brain injury, occurrence, nature, type and outcomes of TBI including risk factor analysis and seasonal variation will be collected through 12-month prospective data collection process. The data will be crucial for evaluating future interventions and outlining policy recommendations. To strengthen the response to TBI, we will develop research capacity among clinicians (surgeons, trauma surgeons, neurosurgeons) in Zambia through hand-on onsite training, short-term workshops and online courses.