Traumatic Brain Injury Across the Lifespan in Zambia

赞比亚一生中的创伤性脑损伤

• 批准号: 10299692
• 负责人: ADNAN A HYDER
• 金额: $ 18.34万
• 依托单位: GEORGE WASHINGTON UNIVERSITY
• 依托单位国家: 美国
• 财政年份: 2021
• 资助国家: 美国
• 起止时间: 2021-09-03 至 2023-08-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/10299692
• 关键词: Accounting; Address; Africa; Age; Area; Brain Diseases; Brain Injuries; Cause of Death; Cell Nucleus; Cessation of life; Clinical; Collaborations; Communities; Consultations; Data; Data Analyses; Data Collection; Data Element; Development; Distance Learning; Economic Burden; Educational Curriculum; Educational process of instructing; Educational workshop; Emergency Situation; Epidemiology; Factor Analysis; Faculty; Future; Generations; Goals; Hand; Health; Health Services Research; Healthcare; Hospital Personnel; Human Resources; Information Systems; Injury; Institutes; Institution; International; Intervention; Intervention Studies; Joints; Leadership; Literature; Longevity; Measures; Mentors; Methodology; Modeling; Nature; Nervous System Trauma; Neurosurgeon; Operative Surgical Procedures; Outcome; Peer Review; Phase; Policies; Poverty; Prevention; Process; Public Health; Public Health Schools; Public Sector; Recommendation; Recording of previous events; Registries; Research; Research Training; Resources; Risk; Risk Factors; Running; Seasonal Variations; Services; Site; Southern Africa; Surgeon; TBI Patients; Teaching Hospitals; Testing; Training; Trauma; Trauma patient; Traumatic Brain Injury; Universities; Vulnerable Populations; Washington; Work; Zambia; base; data infrastructure; data management; data registry; design; digital; disability; electronic registry; experience; health economics; hospital analysis; injury-related death; interest; low and middle-income countries; low income country; mortality; nervous system disorder; online course; programs; prospective; response; scale up; skills; systematic review; webinar; young adult

Project Summary/Abstract The overall goal of the Traumatic Brain Injury Across the Lifespan in Zambia (TBI-Zambia) program is to define the health and economic burden of traumatic brain injuries across the lifespan in Zambia. We will do this by strengthening the local data infrastructure with an electronic registry on traumatic brain injuries (Brain Injury Registry of Lusaka (BraiL)) to collect data on all TBI seen at the University Teaching Hospital. Our approach will involve close collaboration between Milken Institute School of Public Health, the George Washington University (GW), USA, the University of Zambia School of Public Health (UNZA) and its University Teaching Hospital (UTH), Lusaka, Zambia. GW and UNZA share a documented commitment to research training, expertise in application of electronic registries in injuries and health services research, as well as a history of productive collaborative work. UNZA and UTH share a commitment to providing the highest quality service to the under-privileged communities in Zambia, and focus on optimizing outcomes in low-resource settings. Our proposal will leverage the shared interest in understanding the impact of trauma and brain disorders and strengthening research capacity and tackle two critical gaps in addressing these health concerns – create national, disaggregated data on TBI, define their risks and vulnerable groups and the impact of potential interventions and develop a core group of clinicians with research and data management skills. Our TBI-Zambia collaboration will help strengthen capacity within UNZA/UTH and Zambia to apply these methodologies to other areas of health care. The specific aims of this proposal are: (1) To Define core variables and digital platforms for a data registry focused on traumatic brain injuries in Zambia; (2) To Pilot-test a digital traumatic brain injury registry at University Teaching Hospital, University of Zambia for a year; and (3) To Develop a core group of clinicians with research skills and data analysis capacity at University Teaching Hospital, University of Zambia. We will apply the results of the study to reduce the growing burden of TBI across the lifespan and propose a larger intervention study by the end of two years. With TBI patients as our focus, we will develop digital registry, which will be implemented in the Surgical Emergency Unit (where all trauma patients are received, assessed and treatment is initiated) of UTH. Information on the epidemiology of the brain injury, occurrence, nature, type and outcomes of TBI including risk factor analysis and seasonal variation will be collected through 12-month prospective data collection process. The data will be crucial for evaluating future interventions and outlining policy recommendations. To strengthen the response to TBI, we will develop research capacity among clinicians (surgeons, trauma surgeons, neurosurgeons) in Zambia through hand-on onsite training, short-term workshops and online courses.

项目概要/摘要 赞比亚终身创伤性脑损伤 (TBI-赞比亚) 计划的总体目标是 确定赞比亚一生中创伤性脑损伤的健康和经济负担。我们会做 为此，通过创伤性脑损伤电子登记（Brain 卢萨卡伤害登记处 (BraiL)）收集在大学教学医院发现的所有 TBI 数据。我们的 该方法将涉及米尔肯研究所公共卫生学院、乔治 美国华盛顿大学（GW）、赞比亚大学公共卫生学院（UNZA）及其大学 赞比亚卢萨卡教学医院 (UTH)。 GW 和 UNZA 共同致力于研究 培训、在伤害和健康服务研究中应用电子登记方面的专业知识，以及 富有成效的协作工作的历史。 UNZA 和 UTH 共同致力于提供最高质量的服务 为赞比亚的贫困社区提供服务，并重点关注优化资源匮乏地区的成果 设置。我们的提案将利用了解创伤和大脑影响的共同兴趣 疾病和加强研究能力，并解决解决这些健康问题的两个关键差距 – 创建关于 TBI 的国家分类数据，定义其风险和弱势群体以及影响 潜在的干预措施，并培养具有研究和数据管理技能的核心临床医生团队。我们的 TBI-赞比亚合作将有助于加强 UNZA/UTH 和赞比亚应用这些技术的能力 医疗保健其他领域的方法论。本提案的具体目标是： (1) 定义核心 数据登记的变量和数字平台，重点关注赞比亚的创伤性脑损伤； (2) 中试 在赞比亚大学教学医院进行数字创伤性脑损伤登记，为期一年；和（3） 培养具有大学教学研究技能和数据分析能力的核心临床医生团队 赞比亚大学医院。我们将应用研究结果来减轻 TBI 日益增加的负担 并在两年后提出一项更大规模的干预研究。 以 TBI 患者为重点，我们将开发数字登记，该登记将在外科手术中实施 UTH 的急诊科（所有创伤患者均在此接受、评估并开始治疗）。 有关脑损伤的流行病学、TBI 的发生、性质、类型和结果（包括风险）的信息 将通过 12 个月的前瞻性数据收集过程收集因素分析和季节性变化。 这些数据对于评估未来的干预措施和概述政策建议至关重要。加强 为了应对 TBI，我们将培养临床医生（外科医生、创伤外科医生、 通过现场实践培训、短期研讨会和在线课程，在赞比亚培训神经外科医生。