Addressing substance use through CVCT

通过 CVCT 解决物质使用问题

• 批准号: 8810662
• 负责人: Tyrel J Starks
• 金额: $ 26.59万
• 依托单位: HUNTER COLLEGE
• 依托单位国家: 美国
• 财政年份: 2014
• 资助国家: 美国
• 起止时间: 2014-04-01 至 2017-03-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/8810662
• 关键词: 4-hydroxybutyric acid; AIDS prevention; Accounting; Address; Age; Agreement; Alcohol or Other Drugs use; Amphetamines; Anus; Area; Behavior; Centers for Disease Control and Prevention (U.S.); Collaborations; Communication; Communities; Computer software; Counseling; Couples; Crack Cocaine; Data; Data Analyses; Development; Disclosure; Effectiveness; Ethnic Origin; Feedback; Gays; Goals; HIV; HIV Infections; Human immunodeficiency virus test; Individual; Infection; Intervention; Ketamine; Length; Link; Marijuana; Mediation; Methamphetamine; Modeling; Modification; Motivation; Nature; New York City; Nitrates; Participant; Patient Self-Report; Population; Prevention; Prevention Research; Prevention strategy; Protocols documentation; Provider; Randomized; Randomized Controlled Trials; Recruitment Activity; Relative (related person); Reporting; Research; Research Personnel; Risk; Risk Behaviors; Sampling; Seasons; Services; Sex Behavior; Source; Suggestion; Testing; Training; Training Programs; Underserved Population; Ursidae Family; Work; base; ecstasy; efficacy evaluation; emerging adult; experience; follow-up; high risk; innovation; male; member; men; men who have sex with men; novel; public health relevance; reduced substance use; response; sex risk; sexual HIV transmission; sexual relationship; sexual risk taking; skills; technology development; theories; therapy development; transmission process; trial comparing; young adult; young men who have sex with men

DESCRIPTION (provided by applicant): Two factors suggest the need for HIV prevention efforts focused on partnered young men who have sex with men (YMSM). First, HIV rates are rising in this population, which already bears a disproportionate burden of HIV infection. Second, main partnerships - rather than casual partners - account for a majority of new infections, and younger age has been associated with an increased risk of main partner transmission. Substance use remains a critical factor associated with HIV sexual transmission risk behavior. Couples based approaches to HIV testing have been developed for gay men [and the CDC has initiated implementation efforts in the US]; however, existing protocols do not include a focus on substance use. In addition, existing protocols are predicated on the assumption that members of the couple possess adequate assertive communication skills to discuss relationship agreements, which may be underutilized by YMSM. The proposed project will develop a novel intervention to reduce substance use and sexual risk behavior among partnered YMSM through the modification of an existing Couples Voluntary Counseling and Testing (CVCT) protocol originally created by Drs. Sullivan and Stephenson (co-investigators). The new intervention protocol (CVCT+SU) will be informed by qualitative data gathered from 20 HIV testing providers and existing qualitative data from 21 gay couples. In addition to the development of the novel CVCT+SU protocol, the project will develop two brief assertive communication training videos (ACTV) specifically for use with partnered YMSM. [The final two years of the project are devoted to a randomized controlled trial (RCT) comparing the new CVCT+SU to the standard CVCT protocol and testing the added efficacy of the ACTV component. A total of 90 couples will be randomized to one of three conditions (standard CVCT, CVCT+SU, or CVCT+SU and ACTV) using a random adaptive allocation strategy executed using Minim software.] All participants will complete a 3 and 6 month follow up. The study team is led by Dr. Tyrel J. Starks (PI), a new investigator with substantial experience in the analysis f dyadic data, who has collaborated on numerous projects examining the nature of sexual agreements and their association with substance use and HIV transmission risk behavior. He is supported by a team of seasoned investigators, including Drs. Sullivan and Stephenson [(leaders in the CDC's US based CVCT implementation efforts)] as well as Dr. Jeffrey Parsons. The team brings extensive experience in qualitative data analysis with couples and individuals, HIV prevention research, and specifically intervention development.

描述（由申请人提供）：两个因素表明，艾滋病毒预防工作的需要集中在与男性发生性关系的年轻男子（YMSM）。首先，这一人口的艾滋病毒感染率正在上升，他们已经承受了不成比例的艾滋病毒感染负担。第二，主要伴侣-而不是临时伴侣-占新感染的大多数，年龄较小与主要伴侣传播的风险增加有关。药物使用仍然是与艾滋病毒性传播风险行为相关的关键因素。已经为男同性恋者开发了基于夫妇的艾滋病毒检测方法[CDC已在美国启动实施工作];然而，现有的协议不包括对物质使用的关注。此外，现有的协议是基于这样的假设，即夫妇的成员拥有足够的自信的沟通技巧来讨论关系协议，这可能是未充分利用的YMSM。拟议的项目将开发一种新的干预措施，以减少物质使用和性风险行为的合作伙伴YMSM通过修改现有的夫妇自愿咨询和测试（CVCT）协议最初由沙利文博士和斯蒂芬森（共同研究者）。新的干预方案（CVCT+SU）将参考从20个艾滋病毒检测提供者收集的定性数据和21对同性恋夫妇的现有定性数据。除了开发新的CVCT+SU协议外，该项目还将开发两个简短的自信沟通培训视频（ACTV），专门用于合作的YMSM。[The该项目的最后两年致力于一项随机对照试验（RCT），将新的CVCT+SU与标准CVCT方案进行比较，并测试ACTV组分的附加疗效。使用Minim软件执行的随机自适应分配策略，将共计90对夫妇随机分配至三种条件（标准CVCT、CVCT+SU或CVCT+SU和ACTV）之一。]所有参与者将完成3个月和6个月的随访。该研究小组由Tyrel J. Starks博士（PI）领导，他是一位在二元数据分析方面具有丰富经验的新研究员，他曾合作过许多项目，研究性协议的性质及其与物质使用和HIV传播风险行为的关系。他得到了经验丰富的研究人员团队的支持，包括Sullivan博士和斯蒂芬森博士[（CDC在美国的CVCT实施工作的领导者）]以及Jeffrey Parsons博士。该团队在夫妻和个人定性数据分析、艾滋病毒预防研究以及特别是干预措施开发方面拥有丰富的经验。