Addressing substance use through CVCT

通过 CVCT 解决物质使用问题

• 批准号: 8810662
• 负责人: Tyrel J Starks
• 金额: $ 26.59万
• 依托单位: HUNTER COLLEGE
• 依托单位国家: 美国
• 财政年份: 2014
• 资助国家: 美国
• 起止时间: 2014-04-01 至 2017-03-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/8810662
• 关键词: 4-hydroxybutyric acid; AIDS prevention; Accounting; Address; Age; Agreement; Alcohol or Other Drugs use; Amphetamines; Anus; Area; Behavior; Centers for Disease Control and Prevention (U.S.); Collaborations; Communication; Communities; Computer software; Counseling; Couples; Crack Cocaine; Data; Data Analyses; Development; Disclosure; Effectiveness; Ethnic Origin; Feedback; Gays; Goals; HIV; HIV Infections; Human immunodeficiency virus test; Individual; Infection; Intervention; Ketamine; Length; Link; Marijuana; Mediation; Methamphetamine; Modeling; Modification; Motivation; Nature; New York City; Nitrates; Participant; Patient Self-Report; Population; Prevention; Prevention Research; Prevention strategy; Protocols documentation; Provider; Randomized; Randomized Controlled Trials; Recruitment Activity; Relative (related person); Reporting; Research; Research Personnel; Risk; Risk Behaviors; Sampling; Seasons; Services; Sex Behavior; Source; Suggestion; Testing; Training; Training Programs; Underserved Population; Ursidae Family; Work; base; ecstasy; efficacy evaluation; emerging adult; experience; follow-up; high risk; innovation; male; member; men; men who have sex with men; novel; public health relevance; reduced substance use; response; sex risk; sexual HIV transmission; sexual relationship; sexual risk taking; skills; technology development; theories; therapy development; transmission process; trial comparing; young adult; young men who have sex with men

DESCRIPTION (provided by applicant): Two factors suggest the need for HIV prevention efforts focused on partnered young men who have sex with men (YMSM). First, HIV rates are rising in this population, which already bears a disproportionate burden of HIV infection. Second, main partnerships - rather than casual partners - account for a majority of new infections, and younger age has been associated with an increased risk of main partner transmission. Substance use remains a critical factor associated with HIV sexual transmission risk behavior. Couples based approaches to HIV testing have been developed for gay men [and the CDC has initiated implementation efforts in the US]; however, existing protocols do not include a focus on substance use. In addition, existing protocols are predicated on the assumption that members of the couple possess adequate assertive communication skills to discuss relationship agreements, which may be underutilized by YMSM. The proposed project will develop a novel intervention to reduce substance use and sexual risk behavior among partnered YMSM through the modification of an existing Couples Voluntary Counseling and Testing (CVCT) protocol originally created by Drs. Sullivan and Stephenson (co-investigators). The new intervention protocol (CVCT+SU) will be informed by qualitative data gathered from 20 HIV testing providers and existing qualitative data from 21 gay couples. In addition to the development of the novel CVCT+SU protocol, the project will develop two brief assertive communication training videos (ACTV) specifically for use with partnered YMSM. [The final two years of the project are devoted to a randomized controlled trial (RCT) comparing the new CVCT+SU to the standard CVCT protocol and testing the added efficacy of the ACTV component. A total of 90 couples will be randomized to one of three conditions (standard CVCT, CVCT+SU, or CVCT+SU and ACTV) using a random adaptive allocation strategy executed using Minim software.] All participants will complete a 3 and 6 month follow up. The study team is led by Dr. Tyrel J. Starks (PI), a new investigator with substantial experience in the analysis f dyadic data, who has collaborated on numerous projects examining the nature of sexual agreements and their association with substance use and HIV transmission risk behavior. He is supported by a team of seasoned investigators, including Drs. Sullivan and Stephenson [(leaders in the CDC's US based CVCT implementation efforts)] as well as Dr. Jeffrey Parsons. The team brings extensive experience in qualitative data analysis with couples and individuals, HIV prevention research, and specifically intervention development.

描述（由申请人提供）：两个因素表明，需要预防艾滋病毒的努力，重点是与男性发生性关系的年轻人（YMSM）。首先，该人群中的艾滋病毒率正在上升，艾滋病毒感染的负担不成比例。其次，主要合作伙伴关系 - 而不是休闲伙伴 - 占新感染的大部分，而年轻的年龄与主要合作伙伴传播的风险增加有关。使用物质仍然是与HIV性传播风险行为相关的关键因素。为同性恋者开发了基于夫妻的艾滋病毒测试方法[疾病预防控制中心已在美国启动了实施工作]；但是，现有协议不包括对物质使用的重点。此外，现有协议是基于这样的假设，即这对夫妇的成员具有足够的自信沟通技巧来讨论关系协议，而关系协议可能未被YMSM实现。拟议的项目将通过修改现有的夫妻自愿咨询和测试（CVCT）协议，以减少合作YMSM的物质使用和性风险行为的新干预措施。沙利文和斯蒂芬森（共同研究者）。新的干预协议（CVCT+SU）将通过从20个HIV测试提供者和21个同性恋夫妇的现有定性数据收集的定性数据来告知。除了开发新型CVCT+SU协议外，该项目还将开发两个简短的自信通信培训视频（ACTV），专门用于与合作的YMSM一起使用。 [该项目的最后两年专门用于将新的CVCT+SU与标准CVCT协议进行比较的随机对照试验（RCT），并测试了ACTV组件的附加功效。使用最小软件执行的随机自适应分配策略，总共将90对夫妇随机分为三个条件之一（标准CVCT，CVCT+SU或CVCT+SU和ACTV）。]所有参与者将完成3个月和6个月的随访。研究团队由Tyrel J. Starks（PI）博士领导，他是一名新的研究人员，在分析中具有丰富的经验F二元数据，他曾在许多项目上进行了合作，研究了性协议性质及其与药物使用和HIV传播风险行为的关联。他得到了一支经验丰富的调查员团队的支持，包括Drs。 Sullivan和Stephenson [（（CDC美国CVCT实施工作的领导者）]以及Jeffrey Parsons博士。该团队在与夫妻和个人，艾滋病毒预防研究，特别是干预开发方面的定性数据分析方面具有丰富的经验。