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Jules Stein Eye Institute Core Grant for Vision Research

朱尔斯·斯坦眼科研究所视觉研究核心资助

基本信息

批准号：
9003428
负责人：
WAYNE L HUBBELL
金额：
$ 17.46万
依托单位：
UNIVERSITY OF CALIFORNIA LOS ANGELES
依托单位国家：
美国
项目类别：
财政年份：
1997
资助国家：
美国
起止时间：
1997-03-01 至 2015-06-30
项目状态：
已结题

来源：
https://reporter.nih.gov/project-details/9003428
关键词：
Affect Age related macular degeneration American Animal Experiments Animal Model Animals Applications Grants Appointment Award Behavior Binding Proteins Biochemical Biochemistry Biological Blindness Cell physiology Cells Clinical Sciences Cloning Collaborations Contract Services Core Facility Core Grant Cornea Corneal dystrophy DNA Data Defect Development Disease Doctor of Medicine Doctor of Philosophy Drug Monitoring Electrons Electrophysiology (science)Epithelial Evaluation Eye Faculty Fourier Transform Functional Imaging Funding Future Gene Transduction Agent Genes Genetic Glaucoma Goals Grant Growth Health Housing Human Human Resources Image Immunology Inborn Genetic Diseases Individual Institutes International Intervention Joints Knowledge Laboratories Lead Life Light Maintenance Mentors Microscope Microscopy Molecular Molecular Biology Molecular Motors Monitor Monoclonal Antibody R24 Mouse Strains Mus Mutant Strains Mice Mutation Natural History Nerve Degeneration Neurobiology Neuropathy Ophthalmologist Ophthalmology Optical Coherence Tomography Paper Pathologic Processes Patients Phenotype Photoreceptors Physiology Pilot Projects Play Positioning Attribute Process Progress Reports Proteins Psychophysics Publishing Recovery Regulation Reporting Research Research Activity Research Infrastructure Research Institute Research Personnel Research Project Grants Resources Retina Retinal Retinal Degeneration Retinal Ganglion Cells Retinal Pigments Role Schedule Scientist Stem cells Stimulus Students The Sun Time Toxic effect Training Translational Research Vision Vision research Visual Visual system structure Vitamin A Wages base improved in vivo instrument instrumentation interest intravitreal injection laser capture microdissection limbal member new technology operation physical science professor programs receptor research study self-renewal small molecule subretinal injection success theories vision science visual cycle

项目摘要

DESCRIPTION (provided by applicant): The Vision Research Division of the Jules Stein Eye Institute (JSEI) and affiliated Departments at UCLA consists of 15 vision scientists with NEI funding. The objective of the Core Grant for Vision Research at the JSEI is to provide a critically needed infrastructure to support the research activities of this talented group of scientists whose common goal is to increase basic knowledge of the visual system and its disorders. To achieve this objective, personnel and instrument support facilities are organized according to the following modules: (1) Biochemistry and Molecular Biology Instrumentation; (2) Microscopy and Imaging; (3) Machine Shop and (4) Live imaging and Functional Evaluation. These Modules provide instrumentation commonly used by multiple laboratories and are essential to the success of on-going projects as well as to enable new collaborative efforts. Purchase of state-of-the-art instruments in the modules was made possible by the generosity of the JSEI through various donors as well as recent funds from the American Recovery and Reinvestment Act. Support in the form of the Core grant is requested to maintain these Modules through instrument service contracts, and to provide necessary personnel support to assist and train users and provide routine maintenance.

描述（由申请人提供）：朱尔斯斯坦眼科研究所（JSEI）的视觉研究部门和加州大学洛杉矶分校的附属部门由15名视觉科学家组成，由NEI资助。JSEI视觉研究核心补助金的目标是提供急需的基础设施，以支持这群才华横溢的科学家的研究活动，他们的共同目标是增加视觉系统及其疾病的基本知识。为实现这一目标，人员和仪器支持设施按以下方式组织模块：（1）生物化学和分子生物学仪器;（2）显微镜和成像;（3）机械车间和（4）实时成像和功能评估。这些模块提供了多个实验室常用的仪器，对于正在进行的项目的成功以及新的合作努力至关重要。通过JSEI的慷慨捐助以及美国复苏和再投资法案最近的资金，这些模块中最先进的仪器的购买成为可能。需要以核心赠款的形式提供支助，以便通过仪器服务合同维护这些单元，并提供必要的人员支助，以协助和培训用户，并提供日常维护。