Jules Stein Eye Institute Core Grant for Vision Research

描述（由申请人提供）：Jules Stein眼科研究所（JSEI）的视觉研究小组由16名独立的NEI资助的视觉科学家组成（包括1名MERIT， 15名R01, 1名U10和2名R03）。其中两人是参与调查的人员。四名调查人员在上一个奖项期间获得了优异奖。JSEI视觉研究核心基金的目标是提供急需的基础设施，以支持这群才华横溢的科学家的研究，他们的共同目标是增加视觉系统及其疾病的基本知识。为了实现这一目标，人员和仪器支持设施将根据以下模块组织：(1)生物化学；(2)显微镜与成像；(3)机械车间，(4)分子生物学。这些模块提供了多个实验室常用的仪器，对单个项目的成功至关重要。由于JSEI的慷慨捐助，这些模块中最先进的仪器才得以购买，现在只需要通过仪器服务合同来维护这些现有的模块，并为用户培训和日常维护提供必要的人员支持。

DESCRIPTION (provided by applicant): The Vision Research Group housed in the Jules Stein Eye Institute (JSEI) consists of 16 vision scientists with independent NEI funding (including 1 MERIT, 15 R01's, 1 U10 and 2 R03's). Two are participating investigators. Four of the investigators held MERIT awards during the last award period. The objective of the Core Grant for Vision Research at the JSEI is to provide a critically needed infrastructure to support the research of this talented group of scientists, whose common goal is to increase basic knowledge of the visual system and its disorders. To achieve this objective, personnel and instrument support facilities will be organized according to the following modules: (1) Biochemistry; (2) Microscopy and Imaging; (3) Machine Shop, and (4) Molecular Biology. These modules provide instrumentation commonly used by multiple laboratories, and are essential to the success of the individual projects. Purchase of the state-of-the-art instruments in the modules was made possible by the generosity of the JSEI, and additional support is requested only to maintain these existing modules through instrument service contracts, and to provide the necessary personnel support for user training and routine maintenance.